Hasil Pencarian (1)
small molecule | CAS: 2060571-02-8
_PIK3CA_ is one of the most frequently mutated oncogenes, with the resulting mutated p110? protein it encodes playing a central role in tumor cell proliferation.[A264563] Chemotherapeutic agents targeting the PI3K p110? catalytic subunit have shown antitumor …
Kategori:
BCRP/ABCG2 SubstratesCytochrome P-450 CYP2B6 InducersCytochrome P-450 CYP2B6 Inducers (strength unknown)
+4
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Waktu ParuhThe elimination hal…
Vol. DistribusiThe apparent volume…
KlirensThe total clearance…
Genetik
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