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Irinotecan Approved DB00762
small molecule | CAS: 97682-44-5

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_.[A263376] The bis-piperidine side chain in the structure of irinotecan bestows en…

Kategori:
AlkaloidsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +29
Target Protein:
DNA topoisomerase I, mitochondrialDNA topoisomerase 1
Gen Terkait:
SLCO1B1 UGT1A1 UGT1A7 +2
Waktu ParuhAfter intravenous i…
Vol. DistribusiFollowing intraveno…
KlirensThe mean (± standar…
Genetik 5 Varian