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Total database: 17430
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Target
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Hasil Pencarian (8)

biotech | CAS: 472960-22-8

Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to imp…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1192706-52-7

Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).

Kategori:
Adjuvants, ImmunologicAntineoplastic and Immunomodulating AgentsCytochrome P-450 CYP1A2 Inhibitors +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Elbasvir Approved DB11574
small molecule | CAS: 1370468-36-2

Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine d…

Kategori:
Antiinfectives for Systemic UseAntiviral AgentsAntivirals for Systemic Use +18
Target Protein:
Nonstructural protein 5A
Waktu ParuhThe geometric mean …
Vol. DistribusiElbasvir has an est…
KlirensThe clearance of el…
Genetik -
Interferon alfa-2b Approved DB00105
biotech | CAS: 98530-12-2

Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by …

Kategori:
Adjuvants, ImmunologicAlfa InterferonsAmino Acids, Peptides, and Proteins +24
Target Protein:
Interferon alpha/beta receptor 2Interferon alpha-2Interferon alpha/beta receptor 1
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens-
Genetik -
Interferon alfacon-1 Approved DB00069
biotech | CAS: 118390-30-0

Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed …

Kategori:
Adjuvants, ImmunologicAlfa InterferonsAmino Acids, Peptides, and Proteins +16
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu ParuhThe terminal half-l…
Vol. Distribusi-
KlirensClearance, averagi…
Genetik -
Nadofaragene firadenovec Approved DB17381
biotech | CAS: 1823059-12-6

Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFN?2b).[L44381] It was approved by the FDA on December 2022 for the treatment of …

Kategori:
Adeno-associated Viral Vector TherapiesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Peginterferon alfa-2b Approved DB00022
biotech | CAS: 215647-85-1

Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized in…

Kategori:
Adjuvants, ImmunologicAlcoholsAlfa Interferons +34
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Gen Terkait:
IFNL3
Waktu ParuhThe mean half-life …
Vol. Distribusi-
KlirensThe estimated appar…
Genetik 1 Varian
Ropeginterferon alfa-2b Approved DB15119
biotech | CAS: 1335098-50-4

Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term prop…

Kategori:
Adjuvants, ImmunologicAlfa InterferonsAntineoplastic and Immunomodulating Agents +12
Target Protein:
Interferon alpha/beta receptor (IFNAR)
Waktu ParuhRopeginterferon alf…
Vol. DistribusiRopeginterferon alf…
KlirensRopeginterferon alf…
Genetik -