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Total database: 17430
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Target
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Hasil Pencarian (10)

Capromab pendetide Approved DB00089
biotech | CAS: 145464-28-4

Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +13
Target Protein:
Glutamate carboxypeptidase 2
Waktu Paruh-
Vol. Distribusi* 4 ± 2.1 L
Klirens* 42 +/- 22 mL/hr
Genetik -
small molecule | CAS: 131391-70-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 DB11916
small molecule | CAS: 15750-15-9

Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 156586-92-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 chloride Approved DB09490
small molecule | CAS: 50800-85-6

Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxeta…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh2.8 days
Vol. DistribusiIndium In-111 Chlor…
KlirensIndium In-111 Chlor…
Genetik -
biotech | CAS: 138661-00-4

Indium In-111 imciromab pentetate is a mouse monoclonal antibody labelled with the radioisotope Indium-111 which was used for cardiac imaging under the trade name Myoscint, but was withdrawn in 1993.

Kategori:
Diagnostic Radiopharmaceuticals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 oxyquinoline Approved DB09473
small molecule | CAS: 65389-08-4

Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron ca…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu ParuhIndium In 111 decay…
Vol. Distribusi-
KlirensClearance from whol…
Genetik -
Indium In-111 pentetate Approved DB09425
small molecule | CAS: 135998-32-2

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.

Kategori:
Central Nervous SystemDiagnostic RadiopharmaceuticalsRadioactive Diagnostic Agent +1
Waktu ParuhIndium 111 decays b…
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 pentetreotide Approved DB11835
small molecule | CAS: 139096-04-1

Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.

Kategori:
Amino Acids, Peptides, and ProteinsDiagnostic RadiopharmaceuticalsHormones +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 138955-27-8

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.

Kategori:
AcetatesAcids, AcyclicAmines +14
Target Protein:
Tumor-associated glycoprotein 72 (TAG-72)
Waktu Paruh0.8 hours (mammalia…
Vol. Distribusi-
Klirens-
Genetik -