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7

Total database: 17430
Struktur (SMILES)
6 (85.7%)
Target
6 (85.7%)
Genomik
0 (0%)
Referensi
7 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (7)

Dexibuprofen Approved DB09213
small molecule | CAS: 51146-56-6

Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable w…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +18
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1Apoptosis regulator Bcl-2 +9
Waktu ParuhOral tablets contai…
Vol. DistribusiFor more informatio…
KlirensFor more informatio…
Genetik -
Flurbiprofen Approved DB00712
small molecule | CAS: 5104-49-4

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and ankly…

Kategori:
Acids, AcyclicAgents causing hyperkalemiaAgents that produce hypertension +37
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhR-flurbiprofen, 4.7…
Vol. Distribusi* 14 L [Normal Heal…
Klirens-
Genetik -
HZT-501 DB05369
small molecule

HZT-501 is under investigation by Horizon Therapeutics, Inc., a privately held biopharmaceutical company. It has entered Phase 3 clinical trials in March 2007 for reduction of the risk of development of ibuprofen-associated upper gastrointestinal (i.e., gastr…

Target Protein:
Histamine H2 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ibuprofen Approved DB01050
small molecule | CAS: 15687-27-1

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while res…

Kategori:
Acids, CarbocyclicAgents causing angioedemaAgents causing hyperkalemia +47
Target Protein:
Prostaglandin G/H synthase 2C-X-C chemokine receptor type 2Interleukin-8 +10
Waktu ParuhThe serum half-life…
Vol. DistribusiThe apparent volume…
KlirensThe clearance rate …
Genetik -
small molecule | CAS: 64622-45-3

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicPhenylpropionates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Methocarbamol Approved DB00423
small molecule | CAS: 532-03-6

Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether.[A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated …

Kategori:
Acids, AcyclicBenzene DerivativesCarbamates +14
Target Protein:
Carbonic anhydrase 1
Waktu ParuhThe elimination hal…
Vol. DistribusiVolume of distribut…
Klirens0.2-0.8L/h/kg.[L626…
Genetik -
Suprofen Approved DB00870
small molecule | CAS: 40828-46-4

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAnalgesics +23
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -