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9

Total database: 17430
Struktur (SMILES)
8 (88.9%)
Target
5 (55.6%)
Genomik
0 (0%)
Referensi
9 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (9)

Algestone DB18000
small molecule | CAS: 595-77-7

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesContraceptive Agents, FemaleContraceptive Agents, Hormonal +14
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24356-94-3

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesAlgestoneAnti-Inflammatory Agents +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Corticosterone DB04652
small molecule | CAS: 50-22-6

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

Kategori:
11-HydroxycorticosteroidsAdrenal Cortex HormonesAnti-Inflammatory Agents +11
Target Protein:
11-beta-hydroxysteroid dehydrogenase 1Glucocorticoid receptorNuclear receptor coactivator 1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Desoxycortone DB15972
small molecule | CAS: 64-85-7

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesCorticosteroidsCorticosteroids for Systemic Use +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dienogest Approved DB09123
small molecule | CAS: 65928-58-7

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17?-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with eth…

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsAntineoplastic Agents, Hormonal +29
Target Protein:
Progesterone receptorAndrogen receptor
Waktu ParuhElimination half-li…
Vol. DistribusiThe apparent volume…
KlirensThe metabolic clear…
Genetik -
small molecule | CAS: 68-96-2

Deskripsi belum tersedia.

Kategori:
Adrenal Cortex HormonesCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Substrates +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Hydroxyprogesterone caproate Approved DB06789
small molecule | CAS: 630-56-8

Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17?-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was p…

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsCombination Contraceptives (with Estrogen and derivatives) +26
Target Protein:
Progesterone receptor
Waktu ParuhHalf-life = 16 days…
Vol. DistribusiHydroxyprogesterone…
KlirensClearance is highly…
Genetik -
Medroxyprogesterone acetate Approved DB00603
small molecule | CAS: 71-58-9

Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.[A14848] MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporos…

Kategori:
Adrenal Cortex HormonesAntineoplastic AgentsAntineoplastic Agents, Hormonal +46
Target Protein:
Progesterone receptorEstrogen receptorATP-dependent translocase ABCB1 +1
Waktu ParuhOral medroxyprogest…
Vol. DistribusiThe volume of distr…
KlirensThe mean clearance …
Genetik -
Progesterone Approved DB00396
small molecule | CAS: 57-83-0

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can caus…

Kategori:
Adrenal Cortex HormonesBCRP/ABCG2 InducersBCRP/ABCG2 Inhibitors +47
Target Protein:
Progesterone receptorMineralocorticoid receptorEstrogen receptor +7
Waktu ParuhAbsorption half-lif…
Vol. DistribusiWhen administered v…
Klirens**Apparent clearanc…
Genetik -