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Total database: 17430
Struktur (SMILES)
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Target
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Genomik
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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (1)

Naltrexone Approved DB00704
small molecule | CAS: 16590-41-3

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has app…

Kategori:
Agents Causing Muscle ToxicityAlcohol DeterrentsAlimentary Tract and Metabolism +21
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor +1
Gen Terkait:
OPRM1
Waktu Paruh4 hours for naltrex…
Vol. Distribusi* 1350 L [intraveno…
Klirens* ~ 3.5 L/min [afte…
Genetik 1 Varian