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Methotrexate Approved DB00563
small molecule | CAS: 59-05-2

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis.[A180322] This inhibition leads to suppression of inflammation as well as prevention of cell division.[A180322] Because of these effects, methotrexate is of…

Kategori:
Abortifacient AgentsAbortifacient Agents, NonsteroidalAgents Causing Muscle Toxicity +42
Target Protein:
Thymidylate synthaseReduced folate transporterProton-coupled folate transporter +2
Gen Terkait:
ABCC2 MTHFR
Waktu ParuhThe half life of lo…
Vol. DistribusiThe volume of distr…
KlirensMethotrexate cleara…
Genetik 2 Varian