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Total database: 17430
Struktur (SMILES)
7 (87.5%)
Target
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Referensi
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Hasil Pencarian (8)

Cannabidiol Approved DB09061
small molecule | CAS: 13956-29-1

Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocan…

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAnticonvulsants +56
Target Protein:
Cannabinoid receptor 1Cannabinoid receptor 2G-protein coupled receptor 12 +36
Waktu ParuhThe CBD component o…
Vol. DistribusiCannabinoids are di…
Klirens-
Genetik -
small molecule | CAS: 1244-58-2

Cannabidiolic acid is under investigation in clinical trial NCT04103814 (Effect of Topical CBD Cream for Degenerative Hallux Disorders).

Kategori:
Terpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Terpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Dronabinol Approved DB00470
small molecule | CAS: 1972-08-3

Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (??-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabino…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAnalgesics +47
Target Protein:
Cannabinoid receptor 1Cannabinoid receptor 2
Waktu ParuhThe elimination pha…
Vol. DistribusiDronabinol has a la…
KlirensThe value for clear…
Genetik -
biotech

The use of the plant species _Cannabis sativa_ and _Cannabis indica_, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a wave of legalization in North America has changed public …

Kategori:
Agents producing tachycardiaBCRP/ABCG2 InhibitorsCytochrome P-450 CYP1A2 Inducers +51
Target Protein:
Cannabinoid receptor 1Cannabinoid receptor 2G-protein coupled receptor 12 +38
Waktu ParuhThe half life of TH…
Vol. DistribusiAs a very lipophili…
KlirensOne study reported …
Genetik -
Nabilone Approved DB00486
small molecule | CAS: 51022-71-0

Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (??-THC), the primary psychoactive component of cannabis (marijuana). Although structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity thro…

Kategori:
Agents producing tachycardiaAlimentary Tract and MetabolismAntiemetics +30
Target Protein:
Cannabinoid receptor 2Cannabinoid receptor 1
Waktu ParuhThe plasma half-lif…
Vol. DistribusiThe apparent volume…
Klirens-
Genetik -
Nabiximols DB14011
small molecule | CAS: 56575-23-6

Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species _Cannabis sativa L._ that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol). For trademark purposes, purified CBD is branded…

Kategori:
Agents producing tachycardiaAnalgesicsBCRP/ABCG2 Inhibitors +24
Target Protein:
Cannabinoid receptor 1Cannabinoid receptor 2G-protein coupled receptor 12 +41
Waktu ParuhElimination from pl…
Vol. DistribusiCannabinoids are di…
Klirens-
Genetik -
small molecule | CAS: 31262-37-0

Tetrahydrocannabivarin (THCV) is a propyl analogue of tetrahydrocannabinol (?9-THC), one of the primary pharmacological components of [Medical Cannabis]. ?9-THC is currently available in several synthetic forms, including [Dronabinol], while purified or isola…

Kategori:
Agents that produce hypertensionAntidepressive AgentsCentral Nervous System Depressants +3
Target Protein:
Transient receptor potential cation channel subfamily V member 3Cannabinoid receptor 1G-protein coupled receptor 55 +5
Waktu Paruh-
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Genetik -