Hasil Pencarian (2)
small molecule | CAS: 843663-66-1
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity.[A261866] Althoug…
Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiinfectives for Systemic Use
+10
Target Protein:
ATP synthase subunit c
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe volume of distr…
KlirensBedaquiline has a l…
Genetik
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small molecule | CAS: 187235-37-6
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of thi…
Kategori:
Antiinfectives for Systemic UseAntimycobacterialsCytochrome P-450 CYP3A Substrates
+7
Target Protein:
Cyclopropane mycolic acid synthase 1Cyclopropane mycolic acid synthase 2Cyclopropane mycolic acid synthase 3
+5
Waktu ParuhThe elimination hal…
Vol. DistribusiA pharmacokinetic m…
KlirensThe clearance of pr…
Genetik
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