Hasil Filter

5

Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
5 (100.0%)
Genomik
0 (0%)
Referensi
5 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (5)

Amoxicillin Approved DB01060
small molecule | CAS: 26787-78-0

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.[A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum concentrations than ampicillin.[A190648] Amoxicillin was…

Kategori:
Alimentary Tract and MetabolismAmidesAminopenicillins +19
Target Protein:
Penicillin binding protein
Waktu ParuhThe half life of am…
Vol. DistribusiThe central volume …
KlirensThe mean clearance …
Genetik -
Clavulanic acid Approved DB00766
small molecule | CAS: 58001-44-8

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin] to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infectio…

Kategori:
Anti-Bacterial AgentsAnti-Infective Agentsbeta-Lactamase Inhibitors +4
Target Protein:
Bacterial beta-lactamase enzymesBeta-lactamase
Waktu ParuhThe half-life of cl…
Vol. DistribusiA study in 4 health…
KlirensThe clearance of cl…
Genetik -
Erdosteine Approved DB05057
small molecule | CAS: 84611-23-4

Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent. It is a _thiol_ derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis. This dru…

Kategori:
AcetatesAcids, AcyclicCough and Cold Preparations +4
Target Protein:
Chymotrypsin-like elastase family member 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Pantoprazole Approved DB00213
small molecule | CAS: 102625-70-7

Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatmen…

Kategori:
2-PyridinylmethylsulfinylbenzimidazolesAcid ReducersAlimentary Tract and Metabolism +27
Target Protein:
Potassium-transporting ATPase alpha chain 1Potassium-transporting ATPase subunit betaN(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Waktu ParuhAbout 1 hour[F3202]
Vol. DistribusiThe apparent volume…
Klirens**Adults**: With in…
Genetik -
Vonoprazan Approved DB11739
small molecule | CAS: 881681-00-1

Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H<sup>+</sup>, K<sup>+</sup>-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pu…

Kategori:
Alimentary Tract and MetabolismAmidesCytochrome P-450 CYP2B6 Substrates +17
Target Protein:
Hydrogen potassium ATPase
Waktu ParuhVonoprazan has an e…
Vol. DistribusiVonoprazan has an a…
KlirensVonoprazan has an a…
Genetik -