Hasil Pencarian (2)
AVI-4557
DB05447
small molecule
AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can s…
Target Protein:
Hepatocyte nuclear factor 4-alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik
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AVI-5126
DB05726
small molecule
AVI-526 is an improved formulation of [AVI-4557], developed for use on Vein Grafts before use in Heart by-Pass Graft Surgery. AVI-526 works by silencing a gene known as c-myc, a key regulatory gene involved in cardiovascular restenosis. The drug was under inv…
Kategori:
MorpholinesNucleic Acids, Nucleotides, and NucleosidesNucleotides
+3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik
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