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Total database: 17430
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Target
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Hasil Pencarian (2)

Alendronic acid Approved DB00630
small molecule | CAS: 66376-36-1

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].

Kategori:
Agents Causing Muscle ToxicityBisphosphonatesBone Density Conservation Agents +5
Target Protein:
Farnesyl pyrophosphate synthaseHydroxylapatiteTyrosine-protein phosphatase non-receptor type 4 +3
Waktu ParuhDue to alendronic a…
Vol. Distribusi28L[FDA Label].
Klirens71mL/min[FDA Label].
Genetik -
Risedronic acid Approved DB00884
small molecule | CAS: 105462-24-6

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].

Kategori:
Agents Causing Muscle ToxicityBisphosphonatesBone Density Conservation Agents +9
Target Protein:
HydroxylapatiteFarnesyl pyrophosphate synthase
Waktu ParuhThe initial half li…
Vol. Distribusi13.8 L/kg[FDA Label…
KlirensMean renal clearanc…
Genetik -