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Danicopan Approved DB15401
small molecule | CAS: 1903768-17-1

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system.[A263501]…

Kategori:
AminesAmino AcidsAmino Acids, Cyclic +10
Target Protein:
Complement factor D
Waktu ParuhThe mean half-life …
Vol. DistribusiThe apparent volume…
KlirensThe mean apparent c…
Genetik -