Hasil Filter

1

Total database: 17430
Struktur (SMILES)
1 (100.0%)
Target
1 (100.0%)
Genomik
0 (0%)
Referensi
1 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (1)

Leniolisib Approved DB16217
small molecule | CAS: 1354690-24-6

Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase ? (PI3K?). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS).[L45758] APDS is a primary immuno…

Kategori:
Adjuvants, ImmunologicAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors +14
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Waktu ParuhThe effective half-…
Vol. DistribusiThe systemic decay …
KlirensIn one study, healt…
Genetik -