Hasil Pencarian (1)
small molecule | CAS: 254740-64-2
Sparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub>A</sub>R and 0.8 nM for AT<sub>1</sub>R).[A257330,L45300]…
Kategori:
Agents Acting on the Renin-Angiotensin SystemAmidesAngiotensin 2 Receptor Blocker
+30
Target Protein:
Endothelin-1 receptorType-1 angiotensin II receptorType-2 angiotensin II receptor
Waktu ParuhSparsentan has an e…
Vol. DistribusiAt the approved rec…
KlirensSparsentan has a ti…
Genetik
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