Hasil Filter

1

Total database: 17430
Struktur (SMILES)
1 (100.0%)
Target
1 (100.0%)
Genomik
0 (0%)
Referensi
1 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (1)

Baclofen Approved DB00181
small molecule | CAS: 1134-47-0

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patie…

Kategori:
Agents Causing Muscle ToxicityAmino AcidsAmino Acids, Peptides, and Proteins +15
Target Protein:
Gamma-aminobutyric acid type B receptor subunit 2C-X-C chemokine receptor type 4Gamma-aminobutyric acid type B receptor subunit 1
Waktu ParuhThe half-life is 2-…
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
Genetik -