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Difelikefalin Approved DB11938
small molecule | CAS: 1024828-77-0

Difelikefalin (CR845) is an agonist of kappa opioid receptors (KORs) useful in the treatment of pruritus secondary to chronic kidney disease. KORs were first associated with itching in 1984.[A237610] Further investigations revealed that dynorphins, endogenous…

Kategori:
Kappa Opioid Receptor Agonist
Target Protein:
Kappa-type opioid receptor
Waktu ParuhThe half-life of di…
Vol. DistribusiThe mean volume of …
KlirensOne cycle of hemodi…
Genetik -