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Lonafarnib Approved DB06448
small molecule | CAS: 193275-84-2

Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature ageing: skeletal dysplasia, joint contractures, atheroscl…

Kategori:
Alimentary Tract and MetabolismBCRP/ABCG2 InhibitorsBenzocycloheptenes +30
Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta
Waktu ParuhLonafarnib has a me…
Vol. DistribusiIn healthy patients…
Klirens-
Genetik -