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Total database: 17430
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Target
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Hasil Pencarian (2)

Lovastatin Approved DB00227
small molecule | CAS: 75330-75-5

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of _Aspergillus terreus_.[A174550] Originally named Mevinolin, lovastatin belongs to the statin class of…

Kategori:
Agents Causing Muscle ToxicityAnticholesteremic AgentsBSEP/ABCB11 Substrates +21
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseIntegrin alpha-LHistone deacetylase 2
Waktu ParuhLovastatin half-lif…
Vol. DistribusiLovastatin is able …
Klirens-
Genetik -
Pitavastatin Approved DB08860
small molecule | CAS: 147511-69-1

Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and …

Kategori:
Agents Causing Muscle ToxicityAnticholesteremic AgentsBCRP/ABCG2 Substrates +20
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseIntegrin alpha-L
Waktu ParuhThe mean plasma eli…
Vol. DistribusiThe mean volume of …
KlirensFollowing a single …
Genetik -