Hasil Pencarian (2)
small molecule | CAS: 75330-75-5
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of _Aspergillus terreus_.[A174550] Originally named Mevinolin, lovastatin belongs to the statin class of…
Kategori:
Agents Causing Muscle ToxicityAnticholesteremic AgentsBSEP/ABCB11 Substrates
+21
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseIntegrin alpha-LHistone deacetylase 2
Waktu ParuhLovastatin half-lif…
Vol. DistribusiLovastatin is able …
Klirens-
Genetik
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small molecule | CAS: 79902-63-9
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular dis…
Kategori:
Agents Causing Muscle ToxicityAnticholesteremic AgentsBSEP/ABCB11 Substrates
+37
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseIntegrin alpha-LHistone deacetylase 2
Gen Terkait:
KIF6
HMGCR
SLCO1B1
Waktu Paruh4.85 hours[A181571]
Vol. DistribusiRat studies indicat…
Klirens-
Genetik
3 Varian