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Spironolactone Approved DB00421
small molecule | CAS: 52-01-7

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists.[A178192] It promotes sodium and water excretion and potassium retention.[A11837] Spironolactone was originally developed purely f…

Kategori:
Agents causing hyperkalemiaAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension +19
Target Protein:
Mineralocorticoid receptorGlucocorticoid receptorAndrogen receptor +4
Waktu ParuhThe mean half-life …
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