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Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
5 (100.0%)
Genomik
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Referensi
5 (100.0%)

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Hasil Pencarian (5)

(R)-Fluoxetine DB08472
small molecule | CAS: 100568-03-4

An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).

Target Protein:
Transporter
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
(S)-Fluoxetine DB08544
small molecule | CAS: 100568-02-3

An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration (the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine).

Target Protein:
Transporter
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Fluoxetine Approved DB00472
small molecule | CAS: 54910-89-3

Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to ma…

Kategori:
Agents that reduce seizure thresholdAminesAnticholinergic Agents +47
Target Protein:
Sodium-dependent serotonin transporter5-hydroxytryptamine receptor 2CNeuronal acetylcholine receptor subunit alpha-2 +4
Waktu ParuhThe half life of fl…
Vol. DistribusiThe volume of distr…
KlirensThe clearance value…
Genetik -
small molecule

N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide is a solid. This compound belongs to the diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and …

Target Protein:
A disintegrin and metalloproteinase with thrombospondin motifs 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Seladelpar Approved DB12390
small molecule | CAS: 851528-79-5

Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (?) agonist. Seladelpar is a single enantiomer of the R-configuration.[L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary bili…

Kategori:
Acids, AcyclicAntimetabolitesBCRP/ABCG2 Substrates +13
Target Protein:
Peroxisome proliferator-activated receptor delta
Waktu ParuhFollowing administr…
Vol. DistribusiSeladelpar steady s…
KlirensThe apparent oral c…
Genetik -