Hasil Filter

9

Total database: 17430
Struktur (SMILES)
9 (100.0%)
Target
5 (55.6%)
Genomik
1 (11.1%)
Referensi
9 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (9)

small molecule

9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.

Target Protein:
DNA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cabergoline Approved DB00248
small molecule | CAS: 81409-90-7

Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.

Kategori:
Agents that produce hypertensionAlkaloidsAnti-Dyskinesia Agents +31
Target Protein:
D(2) dopamine receptor5-hydroxytryptamine receptor 2BD(3) dopamine receptor +18
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens* renal cl=0,008 L/…
Genetik -
CT-179 DB17114
small molecule | CAS: 1996636-69-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
DA-8031 DB19024
small molecule | CAS: 1148027-74-0

DA-8031 is under investigation in clinical trial NCT01798667 (Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation).

Kategori:
Antidepressive AgentsCentral Nervous System DepressantsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Imipramine Approved DB00458
small molecule | CAS: 50-49-7

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individ…

Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists +70
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent serotonin transporter5-hydroxytryptamine receptor 2A +21
Gen Terkait:
CYP2D6 CYP2D6 CYP2D6 +6
Waktu ParuhImipramine has a me…
Vol. DistribusiImipramine has a hi…
KlirensImipramine has a me…
Genetik 9 Varian
Ivaltinostat DB17118
small molecule | CAS: 936221-33-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Promazine Approved DB00420
small molecule | CAS: 58-40-2

A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +49
Target Protein:
D(2) dopamine receptorMuscarinic acetylcholine receptor M55-hydroxytryptamine receptor 2A +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Triflupromazine Approved DB00508
small molecule | CAS: 146-54-3

A phenothiazine used as an antipsychotic agent and as an antiemetic.

Kategori:
Agents producing tachycardiaAnticholinergic AgentsAntidepressive Agents +26
Target Protein:
D(2) dopamine receptorD(1A) dopamine receptor5-hydroxytryptamine receptor 2B +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -