Hasil Filter

2

Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
2 (100.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (2)

Emtricitabine Approved DB00879
small molecule | CAS: 143491-57-0

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high risk adolescents and adults.[L9010] Emtri…

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +23
Target Protein:
Reverse transcriptase/RNaseHGag-Pol polyprotein
Waktu ParuhThe half life of em…
Vol. DistribusiThe apparent centra…
KlirensEmtricitabine has a…
Genetik -
Lamivudine Approved DB00709
small molecule | CAS: 134678-17-4

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +26
Target Protein:
Gag-Pol polyproteinReverse transcriptase/RNaseHDNA +1
Waktu Paruh5 to 7 hours (healt…
Vol. DistribusiApparent volume of …
Klirens* Renal clearance =…
Genetik -