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6

Total database: 17430
Struktur (SMILES)
6 (100.0%)
Target
5 (83.3%)
Genomik
0 (0%)
Referensi
6 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (6)

small molecule

Deskripsi belum tersedia.

Target Protein:
Cyclin-dependent kinase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Mitogen-activated protein kinase kinase kinase 9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Esmirtazapine DB06678
small molecule | CAS: 61337-87-9

Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacol…

Kategori:
Adrenergic AgentsAdrenergic alpha-2 Receptor AntagonistsAdrenergic alpha-Antagonists +21
Target Protein:
Histamine H1 receptor5-hydroxytryptamine receptor 2Alpha-2 adrenergic receptors
Waktu Paruh10 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Methionine aminopeptidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Mirtazapine Approved DB00370
small molecule | CAS: 85650-52-8

Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.[A177946] This drug was first manufactured by Organon Inc., and received FDA app…

Kategori:
Adrenergic AgentsAdrenergic alpha-2 Receptor AntagonistsAdrenergic alpha-Antagonists +38
Target Protein:
5-hydroxytryptamine receptor 2A5HT3 serotonin receptorAlpha-2A adrenergic receptor +4
Waktu Paruh20-40 hours [FDA la…
Vol. DistribusiThe volume of distr…
KlirensTotal body clearanc…
Genetik -
small molecule | CAS: 141646-08-4

Sanfetrinem cilexetil is under investigation in clinical trial NCT05388448 (EBA, Safety and Tolerability of Sanfetrinem Cilexetil).

Kategori:
Amides
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -