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Total database: 17430
Struktur (SMILES)
47 (95.9%)
Target
11 (22.4%)
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Hasil Pencarian (49)

small molecule | CAS: 1236354-10-1

2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).

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small molecule | CAS: 241144-93-4

5-methyl-2'-fluoroarauracil F-18 is under investigation in clinical trial NCT02809690 (18F-FMAU PET/CT in Diagnosing and Characterizing Prostate Cancer).

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small molecule | CAS: 128592-98-3

Deskripsi belum tersedia.

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Alovudine F-18 DB14930
small molecule | CAS: 287114-80-1

Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).

Kategori:
Anti-Infective AgentsAntiviral AgentsDeoxyribonucleosides +3
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Bfpet F-18 DB15424
small molecule | CAS: 863644-14-8

Bfpet F-18 is under investigation in clinical trial NCT03265431 (Evaluation of PET/MR in Patients Selected for Ablation Therapy).

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Cardiopet DB18913
small molecule | CAS: 855927-17-2

Cardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).

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DCFBC F-18 DB14772
small molecule | CAS: 1169942-33-9

DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).

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DPA-714 F-18 DB19189
small molecule | CAS: 958233-09-5

Deskripsi belum tersedia.

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Fallypride F-18 DB19254
small molecule | CAS: 166173-82-6

Fallypride F-18 is under investigation in clinical trial NCT00846040 (Reduced Carbohydrate Versus Fat in Obese Subjects).

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FET F-18 DB15405
small molecule | CAS: 178433-03-9

FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).

Kategori:
Diagnostic RadiopharmaceuticalsTumour Detection
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small molecule | CAS: 956903-29-0

Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).

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Florbetaben F-18 Approved DB09148
small molecule | CAS: 902143-01-5

Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cogniti…

Kategori:
AminesBenzene DerivativesBenzylidene Compounds +6
Target Protein:
Amyloid-beta precursor protein
Waktu Paruh1 hr
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Florbetapir F-18 Approved DB09149
small molecule | CAS: 956103-76-7

Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis…

Kategori:
AlcoholsAminesCentral Nervous System +6
Target Protein:
Amyloid-beta precursor proteinBeta amyloid plaque
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small molecule | CAS: 1196963-74-2

Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial Cancers With 18F-FSPG).

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small molecule | CAS: 1841444-25-4

Deskripsi belum tersedia.

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Flortaucipir F-18 Approved DB14914
small molecule | CAS: 1522051-90-6

Flortaucipir F-18, also known as <sup>18</sup>F-T807 and <sup>18</sup>F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope.[A203933] It is used as a marker in positron emission tomography (PET) imaging of patients suspected of…

Kategori:
Central Nervous SystemCompounds used in a research, industrial, or household settingContrast Media +6
Target Protein:
Microtubule-associated protein tauAmine oxidase [flavin-containing] AAmine oxidase [flavin-containing] B
Waktu ParuhFlortaucipir F-18 p…
Vol. DistribusiFlortaucipir F-18 i…
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small molecule | CAS: 1565797-57-0

PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).

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small molecule | CAS: 1010702-75-6

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Flotufolastat F-18 Approved DB17851
small molecule | CAS: 2639294-14-5

Flotufolastat F-18 (<sup>18</sup>F-rhPSMA-7.3) is an <sup>18</sup>F-labeled ligand that targets the prostate-specific membrane antigen (PSMA).[A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of <sup>18</sup…

Kategori:
Diagnostic RadiopharmaceuticalsFluorine RadioisotopesPositron Emitting Activity +1
Target Protein:
Glutamate carboxypeptidase 2
Waktu ParuhNot available.
Vol. DistribusiNot available.
KlirensNot available.
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small molecule | CAS: 1037359-47-9

Deskripsi belum tersedia.

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Fluciclatide DB14842
small molecule | CAS: 879894-00-5

Fluciclatide, an investigational radiotracer intended for PET imaging, was under investigation in clinical trials NCT00565721 and NCT01961583 to evaluate its ability to detect tumors and angiogenesis. The conditions targeted by [18F]Fluciclatide in these stud…

Kategori:
AlcoholsAmino Acids, Peptides, and ProteinsEthylene Glycols +4
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Fluciclovine DB15237
small molecule | CAS: 222727-43-7

Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).

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Fluciclovine (18F) Approved DB13146
small molecule | CAS: 222727-39-1

Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging.[A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cel…

Kategori:
CycloparaffinsDiagnostic RadiopharmaceuticalsPositron Emitting Activity +2
Target Protein:
Neutral amino acid transporter B(0)Y+L amino acid transporter 1Cationic amino acid transporter 3 +5
Waktu ParuhFluciclovine is a c…
Vol. DistribusiThe compartmental v…
KlirensFluciclovine renal …
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Fludeoxyglucose (18F) Approved DB09502
small molecule | CAS: 63503-12-8

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered…

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDeoxy Sugars +10
Waktu Paruh10-13 minutes
Vol. DistribusiFludeoxyglucose F 1…
KlirensFludeoxyglucose F 1…
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Fluoride ion F-18 Approved DB09398
small molecule | CAS: 67862-54-8

Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intra…

Kategori:
Diagnostic RadiopharmaceuticalsRadioactive Diagnostic AgentRadiopharmaceutical Activity +1
Waktu Paruh110 min.
Vol. Distribusi0.5-0.7 L/Kg
KlirensRenal clearance for…
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small molecule | CAS: 7574-44-9

Fluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).

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small molecule | CAS: 864084-85-5

Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).

Kategori:
Compounds used in a research, industrial, or household settingDiagnostic Uses of ChemicalsFluorine Radioisotopes +5
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small molecule | CAS: 407582-13-2

Deskripsi belum tersedia.

Kategori:
AlcoholsAminesAmino Alcohols +7
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Fluorodopa (18F) Approved DB13848
small molecule | CAS: 92812-82-3

Fluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes.[L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves …

Kategori:
AminesAmino AcidsAmino Acids, Aromatic +8
Waktu ParuhThe plasma half-lif…
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Fluoroestradiol F-18 Approved DB15690
small molecule | CAS: 94153-53-4

Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions.[L14096] The ability to image ER-positive tumors _in vivo_ is advantageous in that, while helping to visualize tum…

Kategori:
Estradiol CongenersEstranesEstrogens +10
Target Protein:
Estrogen receptorEstrogen receptor beta
Waktu Paruh-
Vol. DistribusiAs fluoroestradiol …
KlirensFluoroestradiol F-1…
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small molecule | CAS: 160388-43-2

Fluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).

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small molecule | CAS: 104613-87-8

Fluoromisonidazole F-18 is under investigation in clinical trial NCT01507428 (Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer).

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small molecule | CAS: 863887-89-2

Flurpiridaz F-18 is a radioactive diagnostic drug indicated for positron emission tomography (PET) myocardial perfusion imaging (MPI), which is an imaging process used in patients with known or suspected coronary artery disease (CAD).[A264519] Flurpiridaz F-1…

Kategori:
Fluorine RadioisotopesRadioactive Diagnostic Agent
Target Protein:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Waktu ParuhFluorine-18 has a h…
Vol. DistribusiFlurpiridaz F-18 di…
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small molecule | CAS: 1211333-21-9

Deskripsi belum tersedia.

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Flutemetamol (18F) Approved DB09151
small molecule | CAS: 765922-62-1

Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate ? amyloid neuritic plaque density in adult patients with cognitive impair…

Kategori:
AminesCentral Nervous SystemCompounds used in a research, industrial, or household setting +11
Target Protein:
Amyloid-beta precursor protein
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small molecule | CAS: 1274863-98-7

Flutriciclamide F-18 is under investigation in clinical trial NCT02350426 (A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques).

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Icrucumab DB14824
biotech | CAS: 1024603-92-6

Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
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Ioflupane F-18 DB16913
small molecule | CAS: 186381-69-1

Deskripsi belum tersedia.

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
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ISO-1 F-18 DB14900
small molecule | CAS: 945992-47-2

ISO-1 F-18 is under investigation in clinical trial NCT00968656 (Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1).

Target Protein:
Sigma intracellular receptor 2
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small molecule | CAS: 156021-12-4

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Me-4(18F)DG DB19207
small molecule | CAS: 915776-36-2

Me-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).

Kategori:
CarbohydratesFluorine RadioisotopesGlycosides
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Misonidazole DB11716
small molecule | CAS: 13551-87-6

Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).

Kategori:
Anti-Infective AgentsAntineoplastic AgentsAntiparasitic Agents +5
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PARPI F-18 DB18657
small molecule | CAS: 1883580-48-0

PARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.

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PBR-06 F-18 DB17020
small molecule | CAS: 1003581-94-9

Deskripsi belum tersedia.

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Piflufolastat F 18 Approved DB14805
small molecule | CAS: 1207181-29-0

Prostate cancer is the most common non-cutaneous malignancy affecting men in North America[A235344] - despite this, an ongoing challenge in prostate cancer therapy is the difficulty in imaging the extent and location of tumor metastases and recurrences.[L3431…

Kategori:
AmidesAmino AcidsAmino Acids, Basic +7
Target Protein:
Glutamate carboxypeptidase 2
Waktu ParuhThe half-life of di…
Vol. DistribusiPiflufolastat F 18 …
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small molecule | CAS: 1226795-18-1

Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).

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Tanaproget DB04787
small molecule | CAS: 304853-42-7

Tanaproget (NSP-989) is an investigational non-steroidal progestin. It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins. Because of this tanaproget …

Kategori:
Heterocyclic Compounds, Fused-RingOxazinesReceptors, Progesterone, agonists +1
Target Protein:
Progesterone receptor
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THK-5351 F-18 DB19223
small molecule | CAS: 1707148-68-2

Deskripsi belum tersedia.

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biotech

Zirconium panitumumab Zr-89 is under investigation in clinical trial NCT05423197 (Study Evaluating Zr-panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous Cell Carcinoma).

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