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Total database: 17430
Struktur (SMILES)
2 (33.3%)
Target
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Hasil Pencarian (6)

Canakinumab Approved DB06168
biotech | CAS: 914613-48-2

Canakinumab is a recombinant, human anti-human-IL-1? monoclonal antibody that belongs to the IgG1/? isotype subclass. It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, w…

Kategori:
Agents reducing cytokine levelsAmino Acids, Peptides, and ProteinsAntibodies +13
Target Protein:
Interleukin-1 beta
Waktu Paruh26 days
Vol. DistribusiThe steady-state vo…
KlirensThe clearance of ca…
Genetik -
MDX-214 DB06110
small molecule

MDX-214 consists of recombinant human epidermal growth factor (EGF) genetically linked to a fully human antibody fragment that is designed to activate cytotoxic killing of cancer cells by immune effector cells. It is developed for the treatment of EGF-R overe…

Target Protein:
Epidermal growth factor receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Oseltamivir Approved DB00198
small molecule | CAS: 196618-13-0

Oseltamivir (marketed as the product Tamiflu?), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the a…

Kategori:
AcetamidesAcetatesAmides +8
Target Protein:
NeuraminidaseSialidase-1Sialidase-2
Waktu ParuhPlasma concentratio…
Vol. DistribusiThe mean volume of …
KlirensRenal clearance (18…
Genetik -
biotech

Streptococcus pneumoniae type 14 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 14 of *Streptococcus pneumoniae*. It is an active immunization for intramuscular or subcut…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 14 individually conjugated to the CRM197 protei…

Kategori:
Actively Acquired ImmunityInactivated Pneumococcal Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Urea C-14 Approved DB09513
small molecule | CAS: 594-05-8

Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of Helicobacter pylori infections. H pylori is a com…

Kategori:
Radioactive Diagnostic Agent
Waktu Paruh14C-urea that is no…
Vol. Distribusi-
Klirens-
Genetik -