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11793

Total database: 17430
Struktur (SMILES)
8607 (73.0%)
Target
6418 (54.4%)
Genomik
102 (0.9%)
Referensi
11793 (100.0%)

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Hasil Pencarian (11793)

Halaman 98 / 236
small molecule | CAS: 148-61-8

Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.

Target Protein:
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialSensor histidine kinase
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small molecule | CAS: 441-61-2

Deskripsi belum tersedia.

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Ethylmorphine DB01466
small molecule | CAS: 76-58-4

A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a sched…

Kategori:
AlkaloidsAnalgesicsAntitussive Agents +22
Target Protein:
Mu-type opioid receptor
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Ethynodiol diacetate Approved DB00823
small molecule | CAS: 297-76-7

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacet…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +19
Target Protein:
Progesterone receptorEstrogen receptor
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Eticlopride DB15492
small molecule | CAS: 84226-12-0

Deskripsi belum tersedia.

Kategori:
AmidesDopamine AgentsDopamine Antagonists +1
Target Protein:
D(2) dopamine receptor
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Etidocaine Approved DB08987
small molecule | CAS: 36637-18-0

Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

Kategori:
AcetanilidesAmidesAmines +10
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Etifoxine DB08986
small molecule | CAS: 21715-46-8

Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiaze…

Kategori:
Anti-Anxiety AgentsCentral Nervous System AgentsCentral Nervous System Depressants +4
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Etigilimab DB18854
biotech | CAS: 2044984-83-8

Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

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Etilevodopa DB06535
small molecule | CAS: 37178-37-3

Deskripsi belum tersedia.

Kategori:
AminesAmino AcidsAmino Acids, Aromatic +11
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small molecule | CAS: 199331-40-3

Etiprednol dicloacetate (BNP-166) is a soft corticosteroid with anti-inflammatory properties that has been indicated in the treatment of asthma and Chron's disease. Anti-asthmatic effects were associated with decreased cytokine production in lipopolysaccharid…

Kategori:
HormonesHormones, Hormone Substitutes, and Hormone Antagonists
Target Protein:
Glucocorticoid receptorInterleukin-1 beta
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Etiracetam DB11868
small molecule | CAS: 33996-58-6

Etiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).

Kategori:
AcetamidesAcetatesAcids, Acyclic +7
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small molecule | CAS: 848779-32-8

Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).

Kategori:
AlcoholsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +9
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Etizolam DB09166
small molecule | CAS: 40054-69-1

Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant,…

Kategori:
Anti-Anxiety AgentsBenzazepinesBenzodiazepine hypnotics and sedatives +17
Target Protein:
GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding SitePlatelet-activating factor receptor
Waktu ParuhThe average elimina…
Vol. DistribusiApparent distributi…
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Etofamide Approved DB13258
small molecule | CAS: 25287-60-9

Etofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].

Kategori:
AcetatesAcids, AcyclicAmebicides +6
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Etofibrate DB08983
small molecule | CAS: 31637-97-5

Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations.

Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityAnticholesteremic Agents +11
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Etohexadiol DB13826
small molecule | CAS: 94-96-2

Deskripsi belum tersedia.

Kategori:
AlcoholsAntiparasitic Products, Insecticides and RepellentsEctoparasiticides, Incl. Scabicides, Insecticides and Repellents +2
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Etokimab DB16661
biotech | CAS: 2022981-44-6

Etokimab is under investigation in clinical trial NCT03614923 (Etokimab in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps (Crswnp)).

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Etonitazene DB01462
small molecule | CAS: 911-65-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Kappa-type opioid receptorDelta-type opioid receptorMu-type opioid receptor
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Etonogestrel Approved DB00294
small molecule | CAS: 54048-10-1

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +18
Target Protein:
Progesterone receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe apparent volume…
KlirensThe clearance rate …
Genetik -
Etoposide Approved DB00773
small molecule | CAS: 33419-42-0

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II bin…

Kategori:
Antineoplastic AgentsAntineoplastic Agents, PhytogenicAntineoplastic and Immunomodulating Agents +38
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh4-11 hours
Vol. DistribusiThe disposition of …
Klirens* Total body cleara…
Genetik -
small molecule | CAS: 433304-61-1

Deskripsi belum tersedia.

Kategori:
Topoisomerase Inhibitors
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Etoricoxib Approved DB01628
small molecule | CAS: 202409-33-4

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib sel…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +34
Target Protein:
Prostaglandin G/H synthase 2
Waktu Paruh22 hours
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Etorphine DB01497
small molecule | CAS: 14521-96-1

A narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for research purposes. Etorphin…

Kategori:
AlkaloidsAnalgesicsCentral Nervous System Agents +10
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor +3
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Etoxeridine DB01505
small molecule | CAS: 469-82-9

Deskripsi belum tersedia.

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Etozoline DB08982
small molecule | CAS: 73-09-6

Etozoline is marketed in Europe under the names Diulozin, Elkapin, and Etopinil. Etozoline is a loop diuretic.

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Etranacogene dezaparvovec Approved DB16791
biotech | CAS: 2156583-26-3

Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX.[L44176] Clotting factors, including factor IX, are necessary components of the signaling cascad…

Kategori:
Adeno-associated Viral Vector TherapiesBlood and Blood Forming OrgansBlood Coagulation Factors +2
Target Protein:
Coagulation factor IX
Waktu Paruh-
Vol. DistribusiIn a study to evalu…
KlirensIn a clinical study…
Genetik -
Etrasimod Approved DB14766
small molecule | CAS: 1206123-37-6

Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P<sub>1,4,5</sub> with no detectable activity on S1P<sub>2</sub> and S1P<sub>3</sub> receptors. S1P receptors are membrane-derived lysophosp…

Kategori:
Acids, AcyclicAntineoplastic and Immunomodulating AgentsCytochrome P-450 CYP2C19 Substrates +11
Target Protein:
Sphingosine 1-phosphate receptor 1Sphingosine 1-phosphate receptor 4Sphingosine 1-phosphate receptor 5
Waktu ParuhThe mean plasma eli…
Vol. DistribusiThe mean apparent v…
KlirensThe apparent steady…
Genetik -
Etravirine Approved DB06414
small molecule | CAS: 269055-15-4

Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the …

Kategori:
Anti-Infective AgentsAnti-Retroviral AgentsAntiinfectives for Systemic Use +24
Target Protein:
Gag-Pol polyproteinGag-Pol polyproteinReverse transcriptase/RNaseH
Waktu ParuhHalf life of 9.05-4…
Vol. DistribusiDistribution of etr…
KlirensRenal clearance of …
Genetik -
Etretinate DB00926
small molecule | CAS: 54350-48-0

Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid. The mechanism of action of etretinate is still incompletely understood although, like retinoic acid, it is thought to interfere with the terminal differentiation o…

Kategori:
AlkenesAntipsoriaticsAntipsoriatics for Systemic Use +12
Target Protein:
Retinoic acid receptor alphaRetinoic acid receptor RXR-alphaRetinoic acid receptor beta +3
Waktu ParuhIn one study, the a…
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Etrinabdione DB18008
small molecule | CAS: 1818428-24-8

Deskripsi belum tersedia.

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Etripamil DB12605
small molecule | CAS: 1593673-23-4

Etripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT).

Kategori:
Acids, CarbocyclicAntiarrhythmic agentsBenzene Derivatives +4
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Etrolizumab DB12189
biotech | CAS: 1044758-60-2

Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is typified by a chronic gastrointestinal inflammatory microenvironment, driven in part by the excessive infiltration and retention of intestinal-homing lymphocytes.[A244564, …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Target Protein:
Integrin beta-7
Waktu ParuhEtrolizumab adminis…
Vol. DistribusiModelling of etroli…
KlirensEtrolizumab has a m…
Genetik -
Etrumadenant DB17506
small molecule | CAS: 2239273-34-6

Deskripsi belum tersedia.

Target Protein:
Adenosine receptor A2aAdenosine receptor A2b
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Etryptamine DB01546
small molecule | CAS: 2235-90-7

In the 1960's, alpha-ethyltryptamine (?ET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. ?ET was an FDA approved antidepressant under the name Monase. H…

Kategori:
AminesBiogenic AminesBiogenic Monoamines +3
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Etybenzatropine DB13468
small molecule | CAS: 524-83-4

Deskripsi belum tersedia.

Kategori:
Agents producing tachycardiaAlkaloidsAnti-Parkinson Drugs +6
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Etynodiol DB13866
small molecule | CAS: 1231-93-2

Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see [DB00823]), not etynodiol.

Kategori:
Adrenal Cortex HormonesCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Substrates +11
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Eucalyptol DB03852
small molecule | CAS: 470-82-6

Eucalyptol is naturally produced cyclic ether and monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. It controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptol is an effe…

Kategori:
AgrochemicalsAlcoholsAnti-Infective Agents +29
Target Protein:
Transient receptor potential cation channel subfamily M member 8
Waktu Paruh-
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Euflavine DB13326
small molecule | CAS: 86-40-8

Deskripsi belum tersedia.

Kategori:
Acridine DerivativesAcridinesAntiseptics and Disinfectants +2
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Eugenol Approved DB09086
small molecule | CAS: 97-53-0

Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain contr…

Kategori:
Acids, CarbocyclicAlkenesAllyl Compounds +11
Target Protein:
Amine oxidase [flavin-containing] BEstrogen receptorEstrogen receptor beta +2
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Eupatilin DB16885
small molecule | CAS: 22368-21-4

Deskripsi belum tersedia.

Kategori:
BenzopyransChromonesDrugs, Chinese Herbal +3
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Genetik -
biotech

Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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European pilchard Approved DB10622
biotech

European pilchard allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Eurotium amstelodami Approved DB15526
biotech

Eurotium amstelodami allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Eurotium herbariorum Approved DB10695
biotech

Eurotium herbariorum is a fungus which can provoke allergic reactions. Eurotium herbariorum extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Evacetrapib DB11655
small molecule | CAS: 1186486-62-3

Evacetrapib has been used in trials studying the basic science and treatment of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Hepatic Insufficiency, and Cardiovascular Disease.

Kategori:
Anticholesteremic AgentsBenzazepinesCholesterol Ester Transfer Proteins, antagonists & inhibitors +3
Target Protein:
Cholesteryl ester transfer protein
Waktu Paruh-
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Evalstotug DB19410
biotech | CAS: 2460399-39-5

Evalstotug is under investigation in clinical trial NCT05271604 (A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck).

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Evans blue DB09361
small molecule | CAS: 314-13-6

Deskripsi belum tersedia.

Kategori:
ArylsulfonatesArylsulfonic AcidsAzo Compounds +7
Target Protein:
Albumin
Waktu Paruh-
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Genetik -
Evenamide DB18775
small molecule | CAS: 1092977-61-1

Deskripsi belum tersedia.

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biotech | CAS: 308064-97-3

Evening primrose oil comes from the extraction from _Oenothera biennis_ seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as [DB00132] and [DB13854].[A33131] Evening …

Kategori:
Agents that reduce seizure thresholdAngiospermsAnti-Inflammatory Agents +26
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Evernimicin DB06431
small molecule | CAS: 109545-84-8

Deskripsi belum tersedia.

Kategori:
Anti-Bacterial AgentsCarbohydratesGlycosides
Waktu Paruh-
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Menampilkan 4851–4900 dari 11793
Sebelumnya Halaman 98 / 236 Berikutnya