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14063

Total database: 17430
Struktur (SMILES)
10481 (74.5%)
Target
8038 (57.2%)
Genomik
107 (0.8%)
Referensi
14063 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (14063)

Halaman 98 / 282
CRA_10762 DB02366
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_10972 DB02989
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_11092 DB03555
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_16847 DB02063
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_17312 DB02084
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_1802 DB02875
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_23653 DB04246
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CRA_9076 DB04215
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Creatinine DB11846
small molecule | CAS: 60-27-5

Creatinine has been used in trials studying the treatment of Amyotrophic Lateral Sclerosis.

Kategori:
Imidazoles
Waktu Paruh-
Vol. Distribusi-
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Crefmirlimab DB17577
biotech | CAS: 2611099-93-3

Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.

Waktu Paruh-
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Crenezumab DB11959
biotech | CAS: 1095207-05-8

Crenezumab has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
Alzheimer Disease, drug therapyAmino Acids, Peptides, and ProteinsAntibodies +8
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Crenolanib DB11832
small molecule | CAS: 670220-88-9

Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.

Kategori:
Antineoplastic AgentsHeterocyclic Compounds, Fused-RingReceptor, Platelet-Derived Growth Factor alpha, antagonists & inhibitors +2
Target Protein:
Platelet-derived growth factor receptor alphaProto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crinecerfont DB18518
small molecule | CAS: 752253-39-7

Deskripsi belum tersedia.

Kategori:
Sulfur Compounds
Target Protein:
Corticotropin-releasing factor receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crisaborole Approved DB05219
small molecule | CAS: 906673-24-3

Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reduci…

Kategori:
Agents for Dermatitis, Excluding CorticosteroidsAnti-Inflammatory AgentsCytochrome P-450 CYP2B6 Inhibitors +9
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B3',5'-cyclic-AMP phosphodiesterase 4C +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Crisdesalazine DB18405
small molecule | CAS: 927685-43-6

Deskripsi belum tersedia.

Kategori:
Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalBenzene Derivatives +3
Target Protein:
Prostaglandin E synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crisugabalin DB19300
small molecule | CAS: 2209104-84-5

Crisugabalin is under investigation in clinical trial NCT06490484 (Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain Who Had an Inadequate Response to Pregabalin).

Waktu Paruh-
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Crizanlizumab Approved DB15271
biotech | CAS: 1690318-25-2

Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease.[L10097] Sickle cell disease is a genetically inherited condition prevalent in the Middle East, Africa, and certai…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
Target Protein:
P-selectin
Waktu ParuhGiven a 5mg/kg dose…
Vol. DistribusiThe volume of distr…
KlirensGiven a 5mg/kg dose…
Genetik -
Crizotinib Approved DB08865
small molecule | CAS: 877399-52-5

Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibrobl…

Kategori:
AminopyridinesAnaplastic lymphoma kinase (ALK) inhibitorsAntineoplastic Agents +32
Target Protein:
ALK tyrosine kinase receptorHepatocyte growth factor receptorProto-oncogene tyrosine-protein kinase ROS +1
Waktu ParuhFollowing single do…
Vol. DistribusiFollowing a single …
KlirensAt steady-state (25…
Genetik -
Crocin DB11874
small molecule | CAS: 42553-65-1

Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.

Kategori:
AlkenesBiological FactorsCondiments +7
Waktu Paruh-
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Klirens-
Genetik -
Crolibulin DB12925
small molecule | CAS: 1000852-17-4

Crolibulin has been used in trials studying the treatment of Solid Tumor and Anaplastic Thyroid Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingPyrans
Waktu Paruh-
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Cromoglicic acid Approved DB01003
small molecule | CAS: 16110-51-3

A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.

Kategori:
Adrenergics, InhalantsAgents for Dermatitis, Excluding CorticosteroidsAlimentary Tract and Metabolism +24
Target Protein:
Heat shock protein HSP 90-alphaProtein S100-P
Waktu Paruh1.3 hours
Vol. Distribusi-
Klirens-
Genetik -
Cronidipine DB09233
small molecule | CAS: 113759-50-5

Cronidipine is a calcium channel blocker.

Waktu Paruh-
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biotech

Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F1…

Kategori:
AntiveninsPassively Acquired ImmunityVenom Neutralization
Target Protein:
Group 10 secretory phospholipase A2
Waktu Paruh12 to 23 hours [FDA…
Vol. Distribusi-
KlirensThis product was sh…
Genetik -
Crotalus atrox antivenin Approved DB13892
biotech

Each year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age group of 18 to 28 [F1…

Kategori:
AntiveninsPassively Acquired ImmunityVenom Neutralization
Waktu Paruh12-23 hours [F113]
Vol. Distribusi-
Klirens-
Genetik -
biotech

Crotalus scutulatus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Crotalus scutulatus (also known as the _Mojave rattlesnake_ [L2856]). The final purified antivenin …

Kategori:
AntiveninsPassively Acquired ImmunityVenom Neutralization
Waktu ParuhApproximately 15 ho…
Vol. Distribusi0.3 L/kg [FDA label]
Klirens32 mL/min (approxim…
Genetik -
Crotamiton Approved DB00265
small molecule | CAS: 483-63-6

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.

Kategori:
AgrochemicalsAminesAniline Compounds +6
Target Protein:
Transient receptor potential cation channel subfamily V member 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crotedumab DB12815
biotech | CAS: 1452387-69-7

Crotedumab has been used in trials studying the treatment of Diabetes Mellitus, Type 2.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crotonaldehyde DB04381
small molecule | CAS: 123-73-9

Deskripsi belum tersedia.

Target Protein:
Transient receptor potential cation channel subfamily A member 1Aldehyde dehydrogenase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crovalimab Approved DB16128
biotech | CAS: 1917321-26-6

Crovalimab is a humanized monoclonal antibody and complement C5 inhibitor.[L50908] It consists of two heavy chains (451 amino acid residues each) and two light chains (217 amino acid residues each).[L50908] First developed by Chugai Pharmaceutical, in collabo…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntineoplastic and Immunomodulating Agents +7
Target Protein:
Complement C5
Waktu ParuhThe mean estimated …
Vol. DistribusiThe mean central an…
KlirensIn PNH treatment-na…
Genetik -
Crozbaciclib DB18081
small molecule | CAS: 2099128-41-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRS-207 DB17323
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
CRS-3123 DB12262
small molecule | CAS: 1013915-71-3

CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cry5B DB17783
biotech

Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_. With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]

Waktu Paruh-
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Genetik -
biotech

Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor …

Waktu Paruh-
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Genetik -
small molecule | CAS: 35825-57-1

Deskripsi belum tersedia.

Kategori:
Drugs, Chinese HerbalPlant Extracts
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cryptoxanthin DB15914
small molecule | CAS: 472-70-8

Deskripsi belum tersedia.

Kategori:
AlkenesBiological FactorsCarotenoids +15
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CSIC002 DB18584
small molecule

CSIC002 is a small-molecule Sema-3A inhibitor. It is being investigated for the treatment of anterior ischemic optic neuropathy.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
CSL-689 DB17726
biotech

CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).

Waktu Paruh-
Vol. Distribusi-
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CSL324 DB16359
biotech

CSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques.[A225626] It has potential applications in various inflammatory conditions such as cystic fibrosis, inflammatory bowel disease…

Waktu Paruh-
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Genetik -
CT-001 DB18284
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CT-179 DB17114
small molecule | CAS: 1996636-69-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
CT-2584 DB13098
small molecule | CAS: 166981-13-1

CT-2584 has been used in trials studying the treatment of Prostate Cancer.

Kategori:
AlkaloidsHeterocyclic Compounds, Fused-RingPhospholipase D, antagonists & inhibitors +2
Target Protein:
Choline-phosphate cytidylyltransferase B
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CT041 DB18288
biotech

CT041 is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).

Waktu Paruh-
Vol. Distribusi-
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Genetik -
CT120 DB18181
biotech

CT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.

Waktu Paruh-
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Genetik -
CTA018 DB05024
small molecule

CTA018 is a member of a new class of vitamin D analogues with a dual mechanism of action, called Vitamin D Signal Amplifiers. This proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent ac…

Target Protein:
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialVitamin D3 receptor
Waktu Paruh-
Vol. Distribusi-
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CTB001 DB18316
biotech

CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.[L48146]

Kategori:
Amino Acids, Peptides, and ProteinsAnticoagulantsAntithrombin Proteins +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTCE-0214 DB05934
small molecule | CAS: 577782-52-6

CTCE-0214 is a stable peptide agonist of stromal cell-derived factor-1 (SDF-1), a key signaling molecule in the proliferation, homing, engraftment and expansion of hematopoietic stem cells and white blood cells.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Inflammatory AgentsBiological Factors +8
Target Protein:
Stromal cell-derived factor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
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CTCE-9908 DB05625
small molecule | CAS: 1030384-98-5

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and Proteins
Target Protein:
C-X-C chemokine receptor type 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTS-1027 DB08490
small molecule | CAS: 193022-04-7

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.

Kategori:
AminesHydroxy AcidsHydroxylamines
Target Protein:
Stromelysin-1Interstitial collagenase72 kDa type IV collagenase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CTS-21166 DB06073
small molecule

CTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far. In 2008, CoMentis revealed this s…

Target Protein:
Beta-secretase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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