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11793

Total database: 17430
Struktur (SMILES)
8607 (73.0%)
Target
6418 (54.4%)
Genomik
102 (0.9%)
Referensi
11793 (100.0%)

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Hasil Pencarian (11793)

Halaman 97 / 236
Etanidazole DB12736
small molecule | CAS: 22668-01-5

Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.

Kategori:
Antineoplastic AgentsImidazolesNitro Compounds +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etavopivat DB18176
small molecule | CAS: 2245053-57-8

Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ETBX-011 DB17464
biotech

ETBX-011 is a cancer vaccine used to treat patients with cancers that express carcinoembryonic antigen (CEA).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ETBX-041 DB17182
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ETBX-061 DB17530
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ETC-1001 DB05866
small molecule

ETC-1001 is Pfizer’s lead oral small molecule product candidate which is intended to be a chronic treatment for individuals with lipid disorders.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
ETC-588 DB05456
small molecule

ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol and other lipids from cells including those in the…

Kategori:
GlycerophosphatesGlycerophospholipidsLipids +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etelcalcetide Approved DB12865
small molecule | CAS: 1262780-97-1

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chron…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Parathyroid AgentsCalcium Homeostasis +3
Target Protein:
Extracellular calcium-sensing receptor
Waktu Paruh3 to 4 days
Vol. Distribusi796 L
Klirens7.66 L/hr
Genetik -
Eteplirsen Approved DB06014
biotech | CAS: 1173755-55-9

Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA.[L40015] Duchenne muscular dystrop…

Kategori:
Antisense OligonucleotidesMorpholinesMusculo-Skeletal System +5
Target Protein:
DMD-001 gene (exon 51 target site)
Waktu ParuhThe elimination hal…
Vol. DistribusiFollowing weekly in…
KlirensThe total clearance…
Genetik -
Etesevimab DB15897
biotech | CAS: 2423948-94-9

Etesevimab (LY-CoV016, also known as JS016) is a fully human and recombinant monoclonal antibody that targets the SARS-CoV-2 surface spike protein receptor binding domain.[L16651,L16661] Under the EUA granted in February 2021, etesevimab is used in combinatio…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Spike glycoprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Etevritamab DB17211
biotech | CAS: 2329692-74-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethacizine DB13645
small molecule | CAS: 33414-33-4

Deskripsi belum tersedia.

Kategori:
Antiarrhythmic agentsAntiarrhythmics, Class IAntiarrhythmics, Class Ic +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethacridine DB13190
small molecule | CAS: 442-16-0

Deskripsi belum tersedia.

Kategori:
Acridine DerivativesAcridinesAminoacridines +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethambutol Approved DB00330
small molecule | CAS: 74-55-5

Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis.[L31743] Ethambutol was first described in the literature in 1961.[A229048] It was developed ou…

Kategori:
AminesAnti-Bacterial AgentsAnti-Infective Agents +23
Target Protein:
Probable arabinosyltransferase CProbable arabinosyltransferase BProbable arabinosyltransferase A
Waktu ParuhEthambutol has a ha…
Vol. DistribusiPatients coinfected…
KlirensPatients coinfected…
Genetik -
small molecule | CAS: 594-45-6

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsHydrocarbons, Acyclic +3
Target Protein:
Platelet basic proteinPhosphonoacetaldehyde hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethanol Approved DB00898
small molecule | CAS: 64-17-5

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical prepara…

Kategori:
Agents Causing Muscle ToxicityAlcoholsAnti-Infective Agents +34
Target Protein:
Gamma-aminobutyric acid receptor subunit alpha-1Glutamate receptor ionotropic, NMDA 3AGlycine receptor subunit alpha-1 +51
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethanolamine oleate Approved DB06689
small molecule | CAS: 2272-11-9

Ethanolamine oleate is a mild sclerosing agent. It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.

Kategori:
Antivaricose TherapyCardiovascular AgentsCompounds used in a research, industrial, or household setting +10
Target Protein:
Calcium ionsCoagulation factor XII
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethaselen DB15051
small molecule | CAS: 217798-39-5

Ethaselen is under investigation in clinical trial NCT02166242 (Ethaselen for the Treatment of Thioredoxin Reductase High Expression Advanced Non-small Cell Lung Cancers).

Kategori:
Selenium Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethinamate Approved DB01031
small molecule | CAS: 126-52-3

Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally …

Kategori:
Acids, Acyclic
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 1
Waktu Paruh2.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethinylestradiol Approved DB00977
small molecule | CAS: 57-63-6

Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.[A191107] These properties were achieved by the substitution…

Kategori:
Adrenal Cortex HormonesAntineoplastic and Immunomodulating AgentsBSEP/ABCB11 inducers +48
Target Protein:
Estrogen receptorNuclear receptor subfamily 1 group I member 2
Waktu ParuhA 30µg oral dose ha…
Vol. DistribusiA 30µg oral dose ha…
KlirensEthinylestradiol ha…
Genetik -
Ethiodized oil Approved DB00965
small molecule | CAS: 8008-53-5

Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl dii…

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethionamide Approved DB00609
small molecule | CAS: 536-33-4

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiinfectives for Systemic Use +9
Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]Nuclear factor erythroid 2-related factor 2Catalase-peroxidase
Waktu Paruh2 to 3 hours
Vol. Distribusi* 93.5 L [healthy v…
Klirens-
Genetik -
Ethoheptazine Approved DB08988
small molecule | CAS: 77-15-6

Ethoheptazine is marketed under the name Zactane. It is a phenazepine based opioid analgesic. It was invented in the 1950s and is related to other drugs such as proheptazine. Ethoheptazine is no longer marketed in the United States.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethosuximide Approved DB00593
small molecule | CAS: 77-67-8

An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.

Kategori:
Agents causing hyperkalemiaAnti-epileptic AgentAntiarrhythmic agents +18
Target Protein:
Voltage-dependent T-type calcium channel subunit alpha-1G
Waktu Paruh53 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethotoin Approved DB00754
small molecule | CAS: 86-35-1

Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabili…

Kategori:
Anti-epileptic AgentAnticonvulsantsCardiovascular Agents +14
Target Protein:
Sodium channel protein type 5 subunit alphaNuclear receptor subfamily 1 group I member 2
Waktu Paruh3 to 9 hours
Vol. Distribusi-
Klirens-
Genetik -
Ethoxyquin DB16866
small molecule | CAS: 91-53-2

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethoxzolamide DB00311
small molecule | CAS: 452-35-7

Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confers the risk for hypoka…

Kategori:
AmidesBenzothiazolesCarbonic Anhydrase Inhibitors +9
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 4Carbonic anhydrase 7 +2
Waktu Paruh2.5-5.5 hours
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15400-53-0

Deskripsi belum tersedia.

Target Protein:
Dihydroneopterin aldolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Dual specificity protein kinase CLK1Dual specificity tyrosine-phosphorylation-regulated kinase 1ADual specificity protein kinase CLK3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Nitric oxide synthase, inducible
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 686723-15-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 548-00-5

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

Kategori:
4-HydroxycoumarinsAnticoagulantsBenzopyrans +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1623-14-9

Deskripsi belum tersedia.

Kategori:
AcidsAcids, NoncarboxylicAnions +7
Target Protein:
CholinesteraseParathion hydrolase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl ferulate Approved DB11285
small molecule | CAS: 4046-02-0

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicCinnamates
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Cholinesterase Inhibitors
Target Protein:
Cholinesterase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl hydroxybenzoate Approved DB13628
small molecule | CAS: 120-47-8

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAntifungals for Dermatological UseAntifungals for Topical Use +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24393-56-4

Deskripsi belum tersedia.

Kategori:
Sunscreen Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 105-40-8

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicCarbamates
Target Protein:
Shiga-like toxin 1 subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl nitrite DB16560
small molecule | CAS: 109-95-5

Deskripsi belum tersedia.

Kategori:
AnionsElectrolytesIons +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 53074-96-7

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 41653-21-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl pyruvate DB05869
small molecule | CAS: 617-35-6

CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-rep…

Kategori:
Keto Acids
Target Protein:
Tumor necrosis factorHigh mobility group protein B1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethyl salicylate Approved DB15576
small molecule | CAS: 118-61-6

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 3439-38-1

Deskripsi belum tersedia.

Target Protein:
Tetanus toxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 107-06-2

Deskripsi belum tersedia.

Kategori:
AlkanesEthaneHydrocarbons, Acyclic +2
Target Protein:
Haloalkane dehalogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylestrenol DB01493
small molecule | CAS: 965-90-2

An anabolic steroid with some progestational activity and little androgenic effect. [PubChem]

Kategori:
Alimentary Tract and MetabolismAnabolic AgentsAnabolic Agents for Systemic Use +9
Target Protein:
Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ethylhexyl methoxycrylene Approved DB11226
small molecule | CAS: 947753-66-4

Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states [F104]. It returns UV filters to their ground states without absorbing sunlight [F104]. It is used as a solve…

Waktu ParuhEthylhexyl methoxyc…
Vol. DistribusiEthylhexyl methoxyc…
KlirensEthylhexyl methoxyc…
Genetik -
Menampilkan 4801–4850 dari 11793
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