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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 95 / 272
CTB001 DB18316
biotech

CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.[L48146]

Kategori:
Amino Acids, Peptides, and ProteinsAnticoagulantsAntithrombin Proteins +8
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CTCE-0214 DB05934
small molecule | CAS: 577782-52-6

CTCE-0214 is a stable peptide agonist of stromal cell-derived factor-1 (SDF-1), a key signaling molecule in the proliferation, homing, engraftment and expansion of hematopoietic stem cells and white blood cells.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Inflammatory AgentsBiological Factors +8
Target Protein:
Stromal cell-derived factor 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CTCE-9908 DB05625
small molecule | CAS: 1030384-98-5

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and Proteins
Target Protein:
C-X-C chemokine receptor type 4
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Ctenocephalides felis Approved DB10693
biotech

Cat flea allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
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CTR-107 DB18583
biotech

CTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.

Waktu Paruh-
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CTS-1027 DB08490
small molecule | CAS: 193022-04-7

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.

Kategori:
AminesHydroxy AcidsHydroxylamines
Target Protein:
Stromelysin-1Interstitial collagenase72 kDa type IV collagenase +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CTS-21166 DB06073
small molecule

CTS-21166 is a small-molecule beta-secretase inhibitor, which is being developed as a disease-modifying treatment for Alzheimer's disease. CTS-21166 is the only BACE1 inhibitor that has passed Phase I clinical trial thus far. In 2008, CoMentis revealed this s…

Target Protein:
Beta-secretase 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CTT-1057 DB14965
small molecule | CAS: 1628717-55-4

CTT-1057 is under investigation in clinical trial NCT03427476 (CTT1057, a Small Molecular Inhibitor of PSMA, as a Novel Imaging Agent of Neovascularization in Renal Cell Carcinoma).

Waktu Paruh-
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CTX130 DB18627
biotech

CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.

Waktu Paruh-
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Cu-64 sartate DB18170
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cu-Cyclam DB03189
small molecule

Deskripsi belum tersedia.

Target Protein:
Lysozyme C
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cudetaxestat DB18203
small molecule | CAS: 1782070-21-6

Deskripsi belum tersedia.

Target Protein:
Autotaxin
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cupric Chloride Approved DB09131
small molecule | CAS: 7447-39-4

Cupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

Kategori:
ElementsMetalsMetals, Heavy +1
Target Protein:
Vitamin K-dependent protein CCystatin-B
Waktu Paruh-
Vol. DistribusiCopper is distribut…
Klirens-
Genetik -
small molecule | CAS: 13479-54-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cupric oxide Approved DB11134
small molecule | CAS: 1317-38-0

Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-m…

Kategori:
Diet, Food, and NutritionElementsFood +6
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing exposure …
KlirensNo pharmacokinetic …
Genetik -
Cupric sulfate Approved DB06778
small molecule | CAS: 7758-98-7

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4?5H2O) and is also known as _blue vitriol_. The anhydrous salt is created by heating the hydrate t…

Kategori:
AntidotesAutonomic AgentsCentral Nervous System Agents +10
Waktu ParuhThe biological half…
Vol. DistribusiThe body of a 70 kg…
Klirens-
Genetik -
small molecule | CAS: 7758-89-6

Deskripsi belum tersedia.

Kategori:
ElementsMetalsMetals, Heavy +1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CUR-1916 DB17838
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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Curcuma aromatica root oil Approved DB11301
biotech | CAS: 94349-73-2

Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called wild tumeric, via steamed distillation. *Curcuma aromatica* belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its…

Kategori:
Biological ProductsPlant OilsPlant Preparations
Waktu Paruh-
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Genetik -
biotech

_Curcuma xanthorrhiza_ oil is extracted from _Curcuma xanthorrhiza_ Roxb., a member of the ginger family (_Zingiberaceae_) that is widely distributed in the region of Southeastern Asia [A33162]. _Curcuma xanthorrhiza_ is also known as Javanese Turmeric or Te…

Waktu ParuhThere are no pharma…
Vol. DistribusiThere are no pharma…
KlirensThere are no pharma…
Genetik -
Curcumin Approved DB11672
small molecule | CAS: 458-37-7

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in [Curcuma xanthorrhiza oil]. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wo…

Kategori:
AlkanesAnalgesicsAnalgesics, Non-Narcotic +29
Target Protein:
Cytochrome P450 3A4Nitric oxide synthase, inducibleCarbonic anhydrase 14 +18
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
small molecule | CAS: 339286-19-0

Deskripsi belum tersedia.

Kategori:
Cytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown)Cytochrome P-450 CYP2B6 Inhibitors +13
Target Protein:
Peroxisome proliferator-activated receptor gammaVitamin D3 receptorATP-binding cassette sub-family C member 5 +2
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiFollowing oral admi…
KlirensNo pharmacokinetic …
Genetik -
Cusatuzumab DB15100
biotech | CAS: 1864871-20-4

CD70 is a ligand expressed on the surface of activated lymphocytes and mature dendritic cells that, in its binding to CD27 receptors, plays an important role in cell proliferation and survival. An overexpression of CD70 can result in the proliferation of mali…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +4
Target Protein:
CD70 antigen
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cutamesine DB06618
small molecule | CAS: 165377-43-5

Deskripsi belum tersedia.

Kategori:
Central Nervous System AgentsNootropic AgentsReceptors, sigma, agonists
Target Protein:
Sigma non-opioid intracellular receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CV-8102 DB19184
biotech

CV-8102 is under investigation in clinical trial NCT03203005 (IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients).

Waktu Paruh-
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CVac Approved DB17351
small molecule

Deskripsi belum tersedia.

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CVN-424 DB18958
small molecule | CAS: 2254706-21-1

CVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).

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CVnCoV Vaccine DB15843
biotech

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
Waktu Paruh-
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Genetik -
CVT-6883 DB05936
small molecule | CAS: 752222-83-6

CVT-6883 is a selective, potent and orally available A2B-adenosine receptor antagonist which CV Therapeutics is investigating for the potential treatment of asthma and other conditions related to inflammation and fibrosis.

Kategori:
Adenosine A2 Receptor AntagonistsHeterocyclic Compounds, Fused-Ring
Target Protein:
Adenosine receptor A2b
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CX-2009 DB16090
biotech | CAS: 2145115-85-9

CX-2009 is under investigation in clinical trial NCT03149549 (PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors).

Waktu Paruh-
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CX157 DB05205
small molecule

CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor of MAO-A designed to have improved oral bioavailability and reduced clearance compared to previous MAO-A inhibitors of this class.

Target Protein:
Amine oxidase [flavin-containing] A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CX516 DB06247
small molecule | CAS: 154235-83-3

Deskripsi belum tersedia.

Kategori:
Receptors, AMPA
Target Protein:
Glutamate receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CXA-10 DB15026
small molecule | CAS: 875685-46-4

CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)).

Kategori:
Anti-Inflammatory AgentsFatty AcidsFatty Acids, Monounsaturated +2
Waktu Paruh-
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Genetik -
CXD101 DB16182
small molecule | CAS: 934828-12-3

CXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).

Waktu Paruh-
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CXL-1020 DB15326
small molecule | CAS: 950834-06-7

CXL-1020 is under investigation in clinical trial NCT01092325 (Safety and Hemodynamic Effects and Pharmacokinetics of CXL-1020 in Patients With Stable Heart Failure).

Waktu Paruh-
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CY-1503 DB17605
small molecule | CAS: 168678-84-0

CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl unit. It was investigated in cardiopulmo…

Kategori:
CarbohydratesPolysaccharides
Waktu Paruh-
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Genetik -
CY301 DB06382
biotech

CY301 (Simplivir) is an investigational gene silencing compound developed by CytoGenix for the treatment of HSV.

Waktu Paruh-
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Genetik -
Cyamemazine DB09000
small molecule | CAS: 3546-03-0

Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due…

Kategori:
Anti-Anxiety AgentsAntidepressive AgentsAntipsychotic Agents +16
Target Protein:
5-hydroxytryptamine receptor 2A5-hydroxytryptamine receptor 1A5-hydroxytryptamine receptor 7 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cyanocobalamin Co-57 Approved DB09385
small molecule | CAS: 13115-03-2

Deskripsi belum tersedia.

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cyanocobalamin Co-60 Approved DB09387
small molecule | CAS: 13422-53-2

Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.

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CYC-065 DB15425
small molecule | CAS: 1070790-89-4

CYC-065 is under investigation in clinical trial NCT03739554 (CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL).

Kategori:
Heterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and NucleosidesNucleosides +3
Target Protein:
Cyclin-dependent kinase 9Cyclin-dependent kinase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cyclacillin Approved DB01000
small molecule | CAS: 3485-14-1

A cyclohexylamido analog of penicillanic acid.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +8
Target Protein:
Penicillin-binding protein 1APenicillin-binding protein 3Penicillin binding protein 2a +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cyclandelate Approved DB04838
small molecule | CAS: 456-59-7

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAntiarrhythmic agents +10
Target Protein:
Voltage-dependent calcium channel subunit alpha-2/delta-1Liver carboxylesterase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6453-60-7

Deskripsi belum tersedia.

Kategori:
DeoxyribonucleotidesNucleic Acids, Nucleotides, and NucleosidesNucleotides +3
Target Protein:
5'(3')-deoxyribonucleotidase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 60-92-4

Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).

Kategori:
Adenine NucleotidesCyclic AMPHeterocyclic Compounds, Fused-Ring +8
Target Protein:
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2cAMP-dependent protein kinase type I-alpha regulatory subunitcAMP-dependent protein kinase type II-beta regulatory subunit +3
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Cyclic GMP DB02315
small molecule | CAS: 7665-99-8

Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger…

Kategori:
Guanine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +5
Target Protein:
cGMP-dependent 3',5'-cyclic phosphodiesterasePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2cAMP-dependent protein kinase type I-alpha regulatory subunit
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cyclizine Approved DB01176
small molecule | CAS: 82-92-8

A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)

Kategori:
AntiemeticsAntihistamines for Systemic UseAutonomic Agents +15
Target Protein:
Histamine H1 receptorSulfotransferase 1E1
Waktu Paruh20 hours
Vol. Distribusi-
Klirens-
Genetik -
Cyclo(his-pro) DB02414
small molecule | CAS: 53109-32-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntioxidantsBiological Factors +6
Target Protein:
Chitinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 97011-16-0

NA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy with Atazanavir and Dexamethasone for COVID-19).

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
Target Protein:
Chitinase B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Cyclobarbital DB13737
small molecule | CAS: 52-31-3

Deskripsi belum tersedia.

Kategori:
Barbiturates, PlainCentral Nervous System DepressantsHypnotics and Sedatives +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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