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15718

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15718 (100.0%)

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Halaman 89 / 315
Catumaxomab Approved DB06607
biotech | CAS: 509077-98-9

Catumaxumab is a trifunctional monoclonal antibody developed for use in cancer treatment. It has affinity for T-cells, accessory immune cells, and cancer cells. Catumaxumab was initially authorized for market by the European Medicines Agency in April 2009 for…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +13
Target Protein:
Low affinity immunoglobulin gamma Fc region receptor II-aLow affinity immunoglobulin gamma Fc region receptor III-ALow affinity immunoglobulin gamma Fc region receptor III-B +3
Waktu ParuhCatumaxomab has an …
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Cauliflower Approved DB10643
biotech

Cauliflower allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
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Cavia porcellus dander Approved DB11019
biotech

Cavia porcellus dander allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Cavia porcellus hair Approved DB10877
biotech

Guinea pig hair is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Cavia porcellus skin Approved DB10416
biotech

Cavia porcellus skin or pelt is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Caviar, unspecified Approved DB14241
biotech

Caviar, unspecified is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Cavosonstat DB14775
small molecule | CAS: 1371587-51-7

Cavosonstat is under investigation in clinical trial NCT02589236 (Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation).

Kategori:
Benzene Derivatives
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Cavrotolimod DB18216
small molecule | CAS: 2378664-12-9

Deskripsi belum tersedia.

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CB-010 DB17711
biotech

CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.[L46158]

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CB-103 DB15279
small molecule | CAS: 218457-67-1

CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).

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CB-1158 DB15286
small molecule | CAS: 2095732-06-0

CB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).

Kategori:
Enzyme Inhibitors
Waktu Paruh-
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CB-5083 DB16874
small molecule | CAS: 1542705-92-9

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Transitional endoplasmic reticulum ATPase
Waktu Paruh-
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CBP-501 DB17277
small molecule | CAS: 565434-85-7

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsCell Cycle ProteinsDual-Specificity Phosphatases +11
Target Protein:
MAP/microtubule affinity-regulating kinase 3MAP kinase-activated protein kinase 2
Waktu Paruh-
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CC-115 DB12740
small molecule | CAS: 1228013-15-7

CC-115 has been used in trials studying the treatment of Prostate Cancer, Neoplasm Metastasis, Ewing's Osteosarcoma, Glioblastoma Multiforme, and Chronic Lymphocytic Leukemia, among others.

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CC-401 DB12432
small molecule | CAS: 395104-30-0

CC-401 has been used in trials studying the treatment of Myeloid Leukemia.

Kategori:
JNK Mitogen-Activated Protein Kinases, antagonists & inhibitorsPyrazoles
Target Protein:
Mitogen-activated protein kinase 8Mitogen-activated protein kinase 9Mitogen-activated protein kinase 10
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CC-90001 DB18445
small molecule | CAS: 1403859-14-2

Deskripsi belum tersedia.

Kategori:
AminesCyclohexanesCycloparaffins
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CCR5 mAb DB05906
biotech

CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (HIV-1). It was generated by HGS using the Abgenix XenoMous…

Target Protein:
C-C chemokine receptor type 5
Waktu Paruh-
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CCT-018159 DB07594
small molecule | CAS: 171009-07-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Heat shock protein HSP 90-alphaHeat shock protein HSP 90-beta
Waktu Paruh-
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CCX-354 DB12963
small molecule | CAS: 1010073-75-2

CCX354-C has been used in trials studying the treatment of Rheumatoid Arthritis.

Target Protein:
C-C chemokine receptor type 1
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CCX915 DB05159
small molecule

CCX915 is developed by ChemoCentryx which targets the chemokine receptor CCR2 and is in phase 1 of clinical trial for the treatment of Multiple Sclerosis and Neurologic Disorders. The CCR2 receptor is thought to be of central importance to inflammatory diseas…

Target Protein:
C-C chemokine receptor type 2
Waktu Paruh-
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Genetik -
biotech

Deskripsi belum tersedia.

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CD564 DB02741
small molecule

Deskripsi belum tersedia.

Target Protein:
Retinoic acid receptor gamma
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Deskripsi belum tersedia.

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CDC-801 DB15640
small molecule | CAS: 192819-27-5

CDC-801 is under investigation in clinical trial NCT00006097 (Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia).

Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4B3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4A
Waktu Paruh-
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CDD-0102 DB16945
small molecule | CAS: 146422-58-4

Deskripsi belum tersedia.

Kategori:
Muscarinic AgonistsOxazolesReceptor, Muscarinic M1, agonists
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CDP323 DB05092
small molecule

CDP323 is an antagonist of the _vascular cell adhesion molecule 1_ (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple Sclerosis (MS). It is considered a small-molecule prodrug…

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +3
Target Protein:
Integrin alpha-4
Waktu Paruh-
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CDX-1135 DB17607
biotech

CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex). It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage.

Kategori:
Amino Acids, Peptides, and ProteinsMembrane ProteinsProteins +1
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CDX-301 DB19293
biotech

CDX-301 is under investigation in clinical trial NCT02129075 (A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma).

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CDX-6210 DB17610
biotech

CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_.

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CDX-6512 DB17841
biotech

CDX-6512 is a modified, gastrointestinal-stable bacterial leucine decarboxylase. Developed by Codexis, it is being investigated for the treatment of homocystinuria And Maple Syrup Urine Disease.[L46651, L46656]

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CE-224535 DB12113
small molecule | CAS: 724424-43-5

CE-224535 has been used in trials studying the treatment of Osteoarthritis.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +4
Target Protein:
P2X purinoceptor 7
Waktu Paruh-
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CE-326597 DB12694
small molecule | CAS: 870615-40-0

CE-326,597 has been used in trials studying the treatment of Obesity.

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Cholecystokinin receptor type A
Waktu Paruh-
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CE-VST01-JC DB17190
biotech

Deskripsi belum tersedia.

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CEB-01 DB18505
small molecule

CEB-01 is a biocompatible polymeric PLGA nanofiber membrane containing the active substance 7-ethyl-10-hydroxycamptothecin

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Cebranopadol DB12830
small molecule | CAS: 863513-91-1

Cebranopadol has been used in trials studying the treatment of Pain, Neoplasms, and Chronic Pain.

Kategori:
Heterocyclic Compounds, Fused-Ring
Target Protein:
Mu-type opioid receptor
Waktu Paruh-
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Ceclazepide DB17270
small molecule | CAS: 1801749-44-9

Deskripsi belum tersedia.

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Cedar leaf oil DB15836
biotech | CAS: 8007-20-3

Deskripsi belum tersedia.

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Cedar oil Approved DB10917
biotech | CAS: 8000-27-9

Cedar oil (Juniperus virginiana) allergenic extract is used in allergenic testing.

Kategori:
Biological ProductsLipidsOils +2
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Cedazuridine Approved DB15694
small molecule | CAS: 1141397-80-9

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such…

Kategori:
Cytidine Deaminase, antagonists & inhibitorsNucleic Acids, Nucleotides, and NucleosidesNucleosides +3
Target Protein:
Cytidine deaminase
Waktu ParuhCedazuridine has a …
Vol. DistribusiThe apparent volume…
KlirensCedazuridine has an…
Genetik -
Cediranib DB04849
small molecule | CAS: 288383-20-0

The novel indole-ether quinazoline Cediranib is a highly potent (IC<sub>50</sub> &lt; 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment of cancer.

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsEnzyme Inhibitors +4
Target Protein:
Vascular endothelial growth factor receptor 2
Waktu Paruh12 to 35 hours
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Cedirogant DB18951
small molecule | CAS: 2055496-11-0

Cedirogant is under investigation in clinical trial NCT05044234 (A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis).

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Cefacetrile DB01414
small molecule | CAS: 10206-21-0

A derivative of 7-aminocephalosporanic acid.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +14
Target Protein:
Penicillin-binding protein 1APenicillin-binding protein 1B
Waktu Paruh1.2 hours
Vol. DistribusiVd of 0.2 to 0.5L/.…
Klirens-
Genetik -
Cefadroxil Approved DB01140
small molecule | CAS: 50370-12-2

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +13
Target Protein:
Penicillin-binding protein 3Penicillin-binding protein 1APenicillin-binding protein 1b +1
Waktu Paruh1.5 hours
Vol. Distribusi-
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Cefalonium DB11385
small molecule | CAS: 5575-21-3

Deskripsi belum tersedia.

Kategori:
Amidesbeta-LactamsHeterocyclic Compounds, Fused-Ring +3
Waktu Paruh-
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Cefaloridine DB09008
small molecule | CAS: 50-59-9

Cephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +13
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Cefalotin Approved DB00456
small molecule | CAS: 153-61-7

Cefalotin is a cephalosporin antibiotic.

Kategori:
Agents that reduce seizure thresholdAmidesAnti-Bacterial Agents +13
Target Protein:
D-alanyl-D-alanine carboxypeptidasePenicillin-binding protein 1APenicillin-binding protein 1b +5
Waktu Paruh30 minutes
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Cefamandole Approved DB01326
small molecule | CAS: 34444-01-4

Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. It is no longer marketed in the United States.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +12
Target Protein:
Penicillin-binding protein 2
Waktu ParuhThe half-life after…
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Cefamandole nafate Approved DB14725
small molecule | CAS: 57268-80-1

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +6
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Cefapirin Approved DB01139
small molecule | CAS: 21593-23-7

Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. Production for use in humans has been discontinued in the United States. Cef…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Target Protein:
Penicillin-binding protein 1A
Waktu Paruh-
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Cefatrizine DB13266
small molecule | CAS: 51627-14-6

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Waktu Paruh-
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