Digital Pharmacy - Dashboard Peneliti

MVA-mBN226B DB17780

biotech

Deskripsi belum tersedia.

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MVA-SARS-2-S DB16432

biotech

MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein[L30453]. MVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to its…

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MVA3000 DB05040

biotech

MVA3000 is an attenuated smallpox vaccine that is being developed for use in people for whom the traditional smallpox vaccine is contraindicated, such as patients with disorders of the immune system or skin conditions such as eczema.

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MVC-COV1901 DB15854

biotech

MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. Medigen has combined forces with Dynavax, which offers an adv…

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MX6 DB05789

small molecule

MX6 is adamantyl group derivatives containing retinoid-related compounds induce apoptosis of cancer cells and therefore may be used for the treatment of cancer, including advanced cancer. More specifically, it has been shown that such adamantyl compounds, e.g…

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Myb34.5 DB17437

biotech

Deskripsi belum tersedia.

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Mycobacterium w. Vaccine DB15798

biotech

The Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. As an immunotherapy, M.w is used against leprosy; the compound also shares antigens with M. tuberculosis. Its use has show…

Kategori:

Biological ProductsComplex MixturesMycobacterium +1

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Mycophenolate mofetil Approved DB00688

small molecule | CAS: 128794-94-5

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH).[A180805] This drug is an immunosuppressant combined with drugs such as [Cyclospor…

Kategori:

Agents Causing Muscle ToxicityAnti-Bacterial AgentsAnti-Infective Agents +23

Target Protein:

Prostaglandin E2 receptor EP2 subtypeInosine-5'-monophosphate dehydrogenase 1Inosine-5'-monophosphate dehydrogenase 2 +1

Waktu ParuhThe average apparen…

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Genetik -

Mycophenolic acid Approved DB01024

small molecule | CAS: 24280-93-1

Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.[L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.[A249170]. Mycophenolic acid is us…

Kategori:

Acids, AcyclicAnti-Bacterial AgentsAnti-Infective Agents +27

Target Protein:

Inosine-5'-monophosphate dehydrogenase 2Inosine-5'-monophosphate dehydrogenase 1

Waktu ParuhThe mean eliminatio…

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Genetik -

MYR-101 DB17075

biotech

MYR-101 (rAAV-Olig001-ASPA) is a recombinant adeno-associated virus (rAAV) vector-based gene therapy intended to treat Canavan disease. Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain. It is caused…

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Myricetin DB02375

small molecule | CAS: 529-44-2

Deskripsi belum tersedia.

Kategori:

BenzopyransChromonesHeterocyclic Compounds, Fused-Ring +1

Target Protein:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformTyrosine-protein kinase JAK1

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Myristic acid DB08231

small molecule | CAS: 544-63-8

Deskripsi belum tersedia.

Kategori:

Fatty AcidsLipidsMyristic Acids

Target Protein:

Tyrosine-protein kinase ABL1Calmodulin-1Calmodulin-3 +45

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Myristica fragrans fruit Approved DB15544

biotech

Myristica fragrans fruit allergenic extract is used in allergenic testing.

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Myrothecium verrucaria Approved DB10819

biotech

Myrothecium verrucaria is a fungus which can provoke allergic reactions. Myrothecium verrucaria extract is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1

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N(2)-carbamimidoyl-N-{2-[4-(3-{4-[(5-carboxyfuran-2-yl)methoxy]-2,3-dichlorophenyl}-1-methyl-1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl}-D-leucinamide DB02581

small molecule

Deskripsi belum tersedia.

Target Protein:

Interleukin-2

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N(2)-succinyl-L-arginine DB02501

small molecule

Deskripsi belum tersedia.

Target Protein:

N-succinylarginine dihydrolase

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N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid DB03458

small molecule | CAS: 111770-79-7

N(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1

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N(6)-(pyridoxal phosphate)-L-lysine DB04083

small molecule | CAS: 2440-59-7

Deskripsi belum tersedia.

Target Protein:

Kynurenine--oxoglutarate transaminase 1Ornithine decarboxylaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferase +8

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N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium DB03945

small molecule | CAS: 3616-04-4

Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.

Kategori:

AminesOnium CompoundsPhosphorylcholine +2

Target Protein:

C-reactive proteinEpididymal sperm-binding protein 1Gamma-hemolysin component B

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N,N,N-trimethylglycinium DB04455

small molecule

A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver …

Target Protein:

Circadian clock protein KaiBGlycine betaine-binding periplasmic protein

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N,N-dimethylarginine DB01686

small molecule | CAS: 30315-93-6

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-es…

Kategori:

Amino AcidsAmino Acids, BasicAmino Acids, Diamino +3

Target Protein:

Nitric oxide synthase, inducibleNitric oxide synthase 3

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N,N-dimethylglycine DB02083

small molecule | CAS: 1118-68-9

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Peptides, and ProteinsEpilepsy, drug therapy +1

Target Protein:

Monomeric sarcosine oxidase

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N-(2-Acetamido)Iminodiacetic Acid DB02810

small molecule | CAS: 26239-55-4

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Cyclic +2

Target Protein:

Peptide deformylasePeptide deformylase

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N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE DB08270

small molecule

Deskripsi belum tersedia.

Target Protein:

Cathepsin K

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N-(3-carboxypropanoyl)-L-norvaline DB08554

small molecule

N-(3-carboxypropanoyl)-L-norvaline is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom. This medication is known to target n-acetylornith…

Target Protein:

Putative ornithine carbamoyltransferaseN-acetylornithine carbamoyltransferase

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N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine DB02943

small molecule

Deskripsi belum tersedia.

Target Protein:

Glutathione S-transferase A1

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N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide DB06942

small molecule

N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. This medication targets the protein prothrombin.

Target Protein:

Prothrombin

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N-(4-MORPHOLINE)CARBONYL-B-(1-NAPHTHYL)-L-ALANINE-L-LEUCINE BORONIC ACID DB04732

small molecule

Deskripsi belum tersedia.

Target Protein:

Proteasome subunit betaProteasome subunit alpha

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N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE DB07653

small molecule

Deskripsi belum tersedia.

Target Protein:

Serine/threonine-protein kinase Chk1

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N-(6,7,9,10,17,18,20,21-octahydrodibenzo[b,k][1,4,7,10,13,16]hexaoxacyclooctadecin-2-yl)acetamide DB07084

small molecule

Deskripsi belum tersedia.

Target Protein:

Outer membrane protein F

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N-(biphenyl-4-ylsulfonyl)-D-leucine DB07446

small molecule

Deskripsi belum tersedia.

Target Protein:

Macrophage metalloelastase

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N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide DB02784

small molecule

Deskripsi belum tersedia.

Target Protein:

Tyrosine-protein phosphatase non-receptor type 1

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N-(carboxycarbonyl)-D-phenylalanine DB08263

small molecule | CAS: 856680-67-6

N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor …

Target Protein:

Hypoxia-inducible factor 1-alpha inhibitor

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N-(ethoxycarbonyl)-L-leucine DB06839

small molecule

Deskripsi belum tersedia.

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N-(indole-3-acetyl)-L-aspartic acid DB07951

small molecule | CAS: 2456-73-7

Deskripsi belum tersedia.

Kategori:

Heterocyclic Compounds, Fused-RingIndoles

Target Protein:

Tryptophan synthase alpha chainTryptophan synthase beta chain

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N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid DB02698

small molecule

Deskripsi belum tersedia.

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N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID DB07816

small molecule

Deskripsi belum tersedia.

Target Protein:

Immunoglobulin heavy constant gamma 1

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N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID DB08635

small molecule

Deskripsi belum tersedia.

Target Protein:

Immunoglobulin heavy variable 3-30

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N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid DB03546

small molecule

Deskripsi belum tersedia.

Target Protein:

Trifunctional purine biosynthetic protein adenosine-3

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N-({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID DB08112

small molecule

Deskripsi belum tersedia.

Target Protein:

UDP-N-acetylmuramoylalanine--D-glutamate ligase

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N-({6-[(4-CYANOBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)-D-GLUTAMIC ACID DB08108

small molecule

Deskripsi belum tersedia.

Target Protein:

UDP-N-acetylmuramoylalanine--D-glutamate ligase

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N-2-Thiophen-2-Yl-Acetamide Boronic Acid DB02094

small molecule

Deskripsi belum tersedia.

Target Protein:

Beta-lactamaseBeta-lactamase

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N-9-Methoxynonyldeoxynojirimycin DB17804

small molecule | CAS: 615253-61-7

Deskripsi belum tersedia.

Kategori:

AlkaloidsCarbohydratesImines +3

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N-acetyl-alpha-neuraminic acid DB03721

small molecule | CAS: 21646-00-4

An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)

Target Protein:

P-selectinE-selectinLiver carboxylesterase 1 +15

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N-acetyl-beta-neuraminic acid DB04265

small molecule | CAS: 19342-33-7

An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)

Target Protein:

Tetanus toxinSialidaseEndo-N-acetylneuraminidase +1

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N-Acetyl-glucosamine thiazoline DB03747

small molecule | CAS: 179030-22-9

N-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid.

Kategori:

Amino SugarsCarbohydratesHexosamines +1

Target Protein:

Beta-hexosaminidase subunit betaB-N-acetylhexosaminidase

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N-Acetyl-L-Citrulline DB02368

small molecule

Deskripsi belum tersedia.

Target Protein:

N-acetylornithine carbamoyltransferase

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N-Acetylalanine DB02518

small molecule | CAS: 97-69-8

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Peptides, and Proteins

Target Protein:

Aldo-keto reductase family 1 member B1

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N-Acetylmethionine DB01646

small molecule | CAS: 65-82-7

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, NeutralAmino Acids, Peptides, and Proteins +2

Target Protein:

Rhodopsino-succinylbenzoate synthase

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N-Acetylproline DB03360

small molecule | CAS: 68-95-1

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +1

Target Protein:

(5R)-carbapenem-3-carboxylate synthase

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