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16004

Total database: 17430
Struktur (SMILES)
12010 (75.0%)
Target
9041 (56.5%)
Genomik
112 (0.7%)
Referensi
16004 (100.0%)

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Hasil Pencarian (16004)

Halaman 83 / 321
Benzoin resin Approved DB11222
biotech | CAS: 9000-05-9

Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus _Styrax_. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the _Styrax_ tree. While benzoin r…

Kategori:
AngiospermsAnti-Infective Agents, LocalBiological Products +11
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Benzonatate Approved DB00868
small molecule | CAS: 104-31-4

Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age.[A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug.[A189519] It works to reduce the a…

Kategori:
AlkanesAminesAntitussive Agents +8
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu ParuhThe half life of be…
Vol. DistribusiThere is limited in…
KlirensThere is limited in…
Genetik -
Benzophenone DB01878
small molecule | CAS: 119-61-9

Benzophenone is the organic compound. Substituted benzophenones such as oxybenzone and dioxybenzone are used in sunscreen.

Kategori:
Benzene DerivativesDermatologicalsKetones +2
Target Protein:
Estrogen receptorEstrogen receptor beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoxonium DB13565
small molecule | CAS: 23884-64-2

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAminesAntiinfectives and Antiseptics for Local Oral Treatment +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoyl peroxide Approved DB09096
small molecule | CAS: 94-36-0

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [a…

Kategori:
Acids, CarbocyclicAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +5
Target Protein:
CatalaseGlutathione peroxidaseAntizyme inhibitor 2 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin F
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoylecgonine DB01515
small molecule | CAS: 519-09-5

Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the…

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 611-73-4

Deskripsi belum tersedia.

Kategori:
Acids, AldehydicAcids, CarbocyclicHydroxy Acids
Target Protein:
2-Hydroxyacid oxidase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 18481-26-0

Deskripsi belum tersedia.

Kategori:
PyrimidinesSulfur CompoundsThiazoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoylpas DB19382
small molecule | CAS: 13898-58-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Beta-lactamaseBeta-lactamase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzphetamine Approved DB00865
small molecule | CAS: 156-08-1

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +28
Target Protein:
Synaptic vesicular amine transporterAlpha-2A adrenergic receptorAlpha-1A adrenergic receptor +1
Waktu Paruh16 to 31 hours
Vol. Distribusi-
Klirens-
Genetik -
Benzquinamide DB00767
small molecule | CAS: 63-12-7

Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine …

Kategori:
Agents producing tachycardiaAnticholinergic AgentsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Histamine H1 receptorMuscarinic acetylcholine receptor M4Muscarinic acetylcholine receptor M1 +3
Waktu Paruh1-1.6 hours (for al…
Vol. Distribusi-
Klirens-
Genetik -
Benzthiazide Approved DB00562
small molecule | CAS: 91-33-8

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium…

Kategori:
DiureticsGenito Urinary System and Sex HormonesGynecological Antiinfectives and Antiseptics +8
Target Protein:
Solute carrier family 12 member 3Carbonic anhydraseCarbonic anhydrase 2 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzydamine Approved DB09084
small molecule | CAS: 642-72-8

Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammato…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +18
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu ParuhApproximately 13 h …
Vol. DistribusiThe volume of distr…
KlirensBenzydamine demonst…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Replicase polyprotein 1ab
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Collagenase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl alcohol Approved DB06770
small molecule | CAS: 100-51-6

Deskripsi belum tersedia.

Kategori:
AlcoholsAnestheticsAnesthetics, Local +18
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl benzoate Approved DB00676
small molecule | CAS: 120-51-4

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl b…

Kategori:
AcaricidesAcids, CarbocyclicAgrochemicals +8
Target Protein:
Hormone-sensitive lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl formate DB04569
small molecule | CAS: 104-57-4

Deskripsi belum tersedia.

Kategori:
Acids, Acyclic
Target Protein:
Thermolysin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 622-78-6

Deskripsi belum tersedia.

Kategori:
IsocyanatesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin FCruzipain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 94-44-0

Deskripsi belum tersedia.

Kategori:
Pyridines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylamine DB02464
small molecule | CAS: 100-46-9

Deskripsi belum tersedia.

Kategori:
AminesBenzene DerivativesBenzyl Compounds
Target Protein:
Serine protease 1Trypsin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylfentanyl DB09182
small molecule | CAS: 1474-02-8

Benzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it was removed from the list after it was found to have minimal opioid activity. Benzylfentan…

Kategori:
Piperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylmorphine DB01573
small molecule | CAS: 14297-87-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylparaben Approved DB14176
small molecule | CAS: 94-18-8

Benzylparaben is used in allergenic testing.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylpenicillin Approved DB01053
small molecule | CAS: 61-33-6

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may al…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +18
Target Protein:
Peptidoglycan synthase FtsIPenicillin-binding protein 1APenicillin-binding protein 1B +5
Waktu ParuhIn adults with norm…
Vol. Distribusi0.53–0.67 L/kg in a…
Klirens560ml/min in health…
Genetik -
Benzylpenicilloyl polylysine Approved DB00895
small molecule | CAS: 31855-75-1

Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluati…

Kategori:
AcetamidesAmidesAnti-Bacterial Agents +9
Target Protein:
High affinity immunoglobulin epsilon receptor subunit gammaHigh affinity immunoglobulin epsilon receptor subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 100-87-8

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonatesAlkanesulfonic Acids +4
Target Protein:
ChymaseSubtilisin BPN'Sigma factor SigB regulation protein RsbQ +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6336-50-1

Deskripsi belum tersedia.

Kategori:
Antithyroid agentsPyrimidinesPyrimidinones +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 627861-07-8

Beperminogene perplasmid is under investigation in clinical trial NCT02144610 (Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia).

Kategori:
Vasoprotectives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bephenium DB13462
small molecule | CAS: 7181-73-9

Deskripsi belum tersedia.

Kategori:
AnthelminticsAntinematodal AgentsAntiparasitic Agents +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepotastine Approved DB04890
small molecule | CAS: 125602-71-3

Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe…

Kategori:
Anti-Allergic AgentsDrugs that are Mainly Renally ExcretedHistamine Antagonists +2
Target Protein:
Histamine H1 receptor
Waktu ParuhElimination half li…
Vol. Distribusi-
Klirens-
Genetik -
Bepranemab DB17945
biotech | CAS: 2244960-75-4

Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepridil Approved DB01244
small molecule | CAS: 64706-54-3

A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a cal…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +20
Target Protein:
Voltage-dependent P/Q-type calcium channel subunit alpha-1AVoltage-dependent T-type calcium channel subunit alpha-1HVoltage-dependent calcium channel subunit alpha-2/delta-2 +7
Waktu Paruh24-50 hours
Vol. Distribusi-
Klirens-
Genetik -
Beractant Approved DB06761
biotech | CAS: 108778-82-1

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral li…

Kategori:
Alveolar Surface Tension ReductionBradycardia-Causing AgentsComplex Mixtures +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beraprost DB05229
small molecule | CAS: 88430-50-6

Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.

Kategori:
AnticoagulantsAntiplatelet agentsAutacoids +17
Target Protein:
Prostacyclin receptor
Waktu Paruh35–40 minutes
Vol. Distribusi-
Klirens-
Genetik -
Berbamine DB18146
small molecule | CAS: 478-61-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAnalgesicsAnalgesics, Non-Narcotic +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berberine Approved DB04115
small molecule | CAS: 2086-83-1

An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.

Kategori:
AlkaloidsBenzylisoquinolinesBerberine Alkaloids +1
Target Protein:
Telomerase reverse transcriptaseBaculoviral IAP repeat-containing protein 5HTH-type transcriptional regulator QacR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1868138-66-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berdazimer Approved DB18712
small molecule

Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate…

Kategori:
Macromolecular SubstancesOrganosilicon CompoundsPolymers +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beremagene geperpavec Approved DB17831
biotech | CAS: 2241888-62-8

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolys…

Kategori:
Administration, TopicalCellular and Gene TherapyCicatrizants +2
Waktu ParuhThere is no informa…
Vol. DistribusiThere is no informa…
KlirensThere is no informa…
Genetik -
Bergamot oil DB14335
biotech | CAS: 8007-75-8

Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bergapten DB12216
small molecule | CAS: 484-20-8

Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).

Kategori:
Anti-Inflammatory AgentsAntipsoriaticsAntipsoriatics for Systemic Use +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berkelium DB12993
small molecule | CAS: 7440-40-6

Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP-544C).

Kategori:
Actinoid Series ElementsElementsElements, Radioactive +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bermekimab DB14947
biotech | CAS: 1401965-15-8

Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beroctocog alfa Approved DB14473
biotech | CAS: 9001-27-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 4101–4150 dari 16004
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