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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Halaman 78 / 315
BMS-188797 DB12619
small molecule | CAS: 172481-83-3

BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
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BMS-214662 DB12234
small molecule | CAS: 195987-41-8

BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3)…

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta
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BMS-275183 DB12144
small molecule | CAS: 355113-98-3

BMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.

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BMS-394136 DB12067
small molecule | CAS: 343246-73-1

BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.

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BMS-564929 DB07286
small molecule | CAS: 627530-84-1

BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.

Target Protein:
Androgen receptor
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BMS-582949 DB12696
small molecule | CAS: 623152-17-0

BMS-582949 has been investigated for the treatment of Psoriasis.

Kategori:
Mitogen-Activated Protein Kinase 14, antagonists & inhibitors
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BMS-599626 DB12318
small molecule | CAS: 714971-09-2

BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.

Kategori:
Acids, AcyclicErbB Receptors, antagonists & inhibitors
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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BMS-690514 DB11665
small molecule | CAS: 859853-30-8

BMS-690514 has been investigated for the treatment of Breast Cancer.

Kategori:
Carbon Radioisotopes
Target Protein:
Vascular endothelial growth factor receptor 2Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2 +1
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BMS-741672 DB19004
small molecule | CAS: 1386991-77-0

BMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).

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BMS-754807 DB15399
small molecule | CAS: 1001350-96-4

BMS-754807 is under investigation in clinical trial NCT00908024 (Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors).

Target Protein:
RAC-alpha serine/threonine-protein kinaseInsulin-like growth factor 1 receptorInsulin receptor
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BMS-770767 DB18902
small molecule | CAS: 1875067-34-7

BMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).

Kategori:
Carbon Radioisotopes
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BMS-777607 DB12064
small molecule | CAS: 1025720-94-8

BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.

Kategori:
AminesPyridines
Target Protein:
Hepatocyte growth factor receptor
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BMS-791826 DB15023
small molecule | CAS: 1008116-73-1

BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).

Kategori:
Heterocyclic Compounds, Fused-RingSulfur CompoundsThiazoles
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BMS-813160 DB16240
small molecule | CAS: 1286279-29-5

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).

Kategori:
Cardiovascular Agents
Target Protein:
C-C chemokine receptor type 2C-C chemokine receptor type 5
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BMS-817399 DB14941
small molecule | CAS: 1202400-18-7

BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).

Kategori:
AmidesAmino AcidsAmino Acids, Branched-Chain +1
Target Protein:
C-C chemokine receptor type 1
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BMS-830216 DB14787
small molecule | CAS: 1197420-06-6

BMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).

Target Protein:
Melanin-concentrating hormone receptor 1
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BMS-833923 DB16844
small molecule | CAS: 1059734-66-5

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Target Protein:
Protein smoothened
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BMS-863233 DB12357
small molecule | CAS: 1169558-38-6

BMS-863233 has been investigated for the treatment of Refractory Hematologic Cancer.

Target Protein:
Cell division cycle 7-related protein kinase
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BMS-903452 DB11773
small molecule | CAS: 1339944-47-6

BMS-903452 has been used in trials studying the treatment of Diabetes.

Kategori:
PyridinesSulfur Compounds
Target Protein:
Glucose-dependent insulinotropic receptor
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BMS-908662 DB12854
small molecule | CAS: 870603-16-0

BMS-908662 has been used in trials studying the treatment of Melanoma and Colorectal Cancer.

Target Protein:
Serine/threonine-protein kinase B-raf
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BMS-911543 DB12591
small molecule | CAS: 1271022-90-2

BMS-911543 has been used in trials studying the treatment of Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingJanus Kinase 2, antagonists & inhibitorsJanus Kinases, antagonists & inhibitors
Target Protein:
Tyrosine-protein kinase JAK2
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BMS-919373 DB15047
small molecule | CAS: 1272353-82-8

BMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).

Target Protein:
Potassium voltage-gated channel subfamily A member 5
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BMS-929075 DB14950
small molecule | CAS: 1217338-97-0

BMS-929075 is under investigation in clinical trial NCT01525212 (Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients).

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BMS-955176 DB15193
small molecule | CAS: 1392312-45-6

BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +2
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BMS-986012 DB14831
biotech | CAS: 1894272-37-7

BMS-986012 is a human antifucosyl-GM1 antibody. It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).

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BMS-986020 DB14948
small molecule | CAS: 1257213-50-5

BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers).

Target Protein:
Lysophosphatidic acid receptor 1
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BMS-986094 DB11966
small molecule | CAS: 1234490-83-5

INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.

Kategori:
Guanine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
Genome polyprotein
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BMS-986104 DB15214
small molecule | CAS: 1622180-31-7

BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects).

Target Protein:
Sphingosine 1-phosphate receptor 1
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BMS-986115 DB13126
small molecule | CAS: 1584647-27-7

BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.

Kategori:
BenzazepinesEnzyme InhibitorsGamma Secretase Inhibitors and Modulators +1
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BMS-986141 DB14942
small molecule | CAS: 1478711-48-6

BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
PRKC apoptosis WT1 regulator protein
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BMS-986142 DB15291
small molecule | CAS: 1643368-58-4

BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).

Target Protein:
Tyrosine-protein kinase BTK
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BMS-986158 DB15435
small molecule | CAS: 1800340-40-2

BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).

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BMS-986251 DB19007
small molecule | CAS: 2041841-30-7

BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).

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BMS-986278 DB18011
small molecule | CAS: 2170126-74-4

Deskripsi belum tersedia.

Target Protein:
Lysophosphatidic acid receptor 1
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BMS184394 DB03466
small molecule

Deskripsi belum tersedia.

Target Protein:
Retinoic acid receptor gamma
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BMSC-0013 DB02474
small molecule

Deskripsi belum tersedia.

Target Protein:
Cholera enterotoxin subunit B
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small molecule | CAS: 1379866-50-8

Deskripsi belum tersedia.

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BN-201 DB18295
small molecule | CAS: 1361200-34-1

Deskripsi belum tersedia.

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BN-82451 DB16950
small molecule | CAS: 335242-75-6

Deskripsi belum tersedia.

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BN104 DB18172
small molecule

Deskripsi belum tersedia.

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biotech

BN?Brachyury vaccine is a novel prime?boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)?Brachyury booster vaccine.[A255173]

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BNC-210 DB19048
small molecule | CAS: 1020634-41-6

BNC-210 is under investigation in clinical trial NCT04951076 (A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-traumatic Stress Disorder (PTSD)).

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BNC105 DB06313
small molecule | CAS: 945772-45-2

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesEthersHeterocyclic Compounds, Fused-Ring +3
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BNT-162A1 DB16402
biotech | CAS: 2417899-74-0

BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
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BNT111 DB18177
biotech

BNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.

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biotech

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intram…

Kategori:
Experimental Unapproved Treatments for COVID-19
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biotech

BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +11
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BNT162b2 Omicron (KP.2) Approved DB19415
biotech

BNT162b2 Omicron (KP.2) is COVID-19 mRNA vaccine encoding the viral spike (S) glycoprotein of SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient in the 2024-2025 formulation of Pfizer-BioNTech's Comirnaty vaccine.[L36030]

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BNT162b3 DB16442
biotech

The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to [BNT162b2], BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinica…

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biotech

BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery v…

Kategori:
Experimental Unapproved Treatments for COVID-19
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