Hasil Filter

14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
Referensi
14494 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (14494)

Halaman 77 / 290
Capsicum oleoresin Approved DB11131
biotech | CAS: 8023-77-6

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such a…

Kategori:
Biological ProductsComplex MixturesPharmaceutical Preparations +1
Target Protein:
Transient receptor potential cation channel subfamily V member 1
Waktu ParuhFor pharmacokinetic…
Vol. DistribusiFor pharmacokinetic…
KlirensFor pharmacokinetic…
Genetik -
Captodiame DB09014
small molecule | CAS: 486-17-9

Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.

Kategori:
Anti-Anxiety AgentsAntidepressive AgentsCentral Nervous System Depressants +7
Target Protein:
5-hydroxytryptamine receptor 2CSigma non-opioid intracellular receptor 1D(3) dopamine receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Captopril Approved DB01197
small molecule | CAS: 62571-86-2

Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldos…

Kategori:
ACE Inhibitors and DiureticsAgents Acting on the Renin-Angiotensin SystemAgents causing angioedema +19
Target Protein:
Angiotensin-converting enzyme72 kDa type IV collagenaseMatrix metalloproteinase-9 +2
Waktu Paruh2 hours
Vol. Distribusi-
Klirens-
Genetik -
CAR BCMA-CS1 DB17313
biotech

CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Caramiphen DB11504
small molecule | CAS: 77-22-5

Caramiphen is a cholinergic antagonist used in Parkinson's disease. Additionally, it is used, in combination with [phenylpropanolamine], as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.

Kategori:
Cycloparaffins
Target Protein:
Muscarinic acetylcholine receptor M2Muscarinic acetylcholine receptor M1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Caraway seed Approved DB10671
biotech

Caraway seed allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Poly [ADP-ribose] polymerase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbamazepine Approved DB00564
small molecule | CAS: 298-46-4

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is …

Kategori:
AnalgesicsAnalgesics, Non-NarcoticAnticonvulsants +65
Target Protein:
Voltage-gated sodium channel alpha subunitNeuronal acetylcholine receptor subunit alpha-4Nuclear receptor subfamily 1 group I member 2
Gen Terkait:
SCN1A HSPA1L HSPA1A +7
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe volume of distr…
KlirensIn a pharmacokineti…
Genetik 10 Varian
Carbamic Acid DB04261
small molecule | CAS: 463-77-4

Deskripsi belum tersedia.

Kategori:
Acids, Acyclic
Target Protein:
Beta-lactamaseBeta-lactamase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbamide peroxide Approved DB11129
small molecule | CAS: 124-43-6

Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Som…

Kategori:
AmidesAnionsAnti-Infective Agents +14
Waktu ParuhNo established phar…
Vol. DistribusiNo established phar…
KlirensNo established phar…
Genetik -
Carbamoylcholine Approved DB00411
small molecule | CAS: 462-58-8

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932.[A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects. Carbamoylcholine w…

Kategori:
AlcoholsAminesAmino Alcohols +28
Target Protein:
Muscarinic acetylcholine receptor M1Muscarinic acetylcholine receptor M2Neuronal acetylcholine receptor subunit alpha-2 +2
Waktu ParuhData regarding the …
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
Carbapenem DB18912
small molecule | CAS: 78854-41-8

Deskripsi belum tersedia.

Kategori:
AmidesAnti-Bacterial Agentsbeta-Lactams +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
3-dehydroquinate synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbarsone DB11382
small molecule | CAS: 121-59-5

Carbarsone is a compound used as an antiprotozoal drug for the treatment of histomoniasis (or blackhead disease) in addition to other infectious diseases in chicken and turkeys. It belongs to the _organoarsenic_ group of chemical compounds and has antiamebic …

Kategori:
Arsenicals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbaryl DB15930
small molecule | CAS: 63-25-2

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAgrochemicalsCarbamates +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5749-67-7

Deskripsi belum tersedia.

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAmides +17
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbazochrome DB09012
small molecule | CAS: 69-81-8

Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone [A19747]. In the future this may prevent excessive blood flow during surgical…

Kategori:
Biological FactorsBlood and Blood Forming OrgansCoagulants +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 70063-04-6

Deskripsi belum tersedia.

Kategori:
Biological FactorsCoagulantsHematologic Agents +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbazole DB07301
small molecule | CAS: 86-74-8

Deskripsi belum tersedia.

Kategori:
CarcinogensHeterocyclic Compounds, Fused-RingIndoles +2
Target Protein:
Ferredoxin CarAcTerminal oxygenase component of carbazole
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Fatty acid-binding protein, adipocyteFatty acid-binding protein 5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbendazim DB13009
small molecule | CAS: 10605-21-7

Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Acids, AcyclicAgrochemicalsAnthelmintics +10
Target Protein:
Aryl hydrocarbon receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbenicillin Approved DB00578
small molecule | CAS: 4697-36-3

Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +11
Target Protein:
Penicillin-binding proteinBeta-lactamase Toho-1
Waktu Paruh1 hour
Vol. Distribusi-
Klirens-
Genetik -
Carbenoxolone DB02329
small molecule | CAS: 5697-56-3

An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [PubChem]

Kategori:
Alimentary Tract and MetabolismAnti-Ulcer AgentsDrugs for Acid Related Disorders +5
Target Protein:
11-beta-hydroxysteroid dehydrogenase 13-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbetocin Approved DB01282
small molecule | CAS: 37025-55-1

Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

Kategori:
Amino Acids, Peptides, and ProteinsDelayed-Action PreparationsDrug Delivery Systems +14
Target Protein:
Oxytocin receptor
Waktu Paruh40 minutes
Vol. Distribusi-
Klirens-
Genetik -
Carbidopa Approved DB00190
small molecule | CAS: 28860-95-9

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activit…

Kategori:
AminesAnti-Dyskinesia AgentsAnti-Parkinson Drugs +12
Target Protein:
Aromatic-L-amino-acid decarboxylase
Waktu ParuhThe reported half-l…
Vol. DistribusiThe volume of distr…
KlirensThe reported cleara…
Genetik -
Carbimazole Approved DB00389
small molecule | CAS: 22232-54-8

An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.

Kategori:
Agents Causing Muscle ToxicityAntithyroid agentsHormone Antagonists +5
Target Protein:
Thyroid peroxidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbinoxamine Approved DB00748
small molecule | CAS: 486-16-8

Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-recepto…

Kategori:
Aminoalkyl EthersAntihistamines for Systemic UseCentral Nervous System Depressants +8
Target Protein:
Histamine H1 receptor
Waktu Paruh10 to 20 hours
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Pro-cathepsin H
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbocisteine Approved DB04339
small molecule | CAS: 638-23-3

Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and…

Kategori:
Amino AcidsAmino Acids, DicarboxylicAmino Acids, Neutral +10
Target Protein:
Kelch-like ECH-associated protein 1Nuclear factor erythroid 2-related factor 2PI-PLC X domain-containing protein 3 +1
Waktu ParuhThe plasma half-lif…
Vol. DistribusiCarbocisteine penet…
KlirensClearance informati…
Genetik -
Carbocromen Approved DB13279
small molecule | CAS: 804-10-4

Carbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development [L5635].

Kategori:
BenzopyransCardiac TherapyCardiovascular Agents +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbomer DB15649
small molecule | CAS: 9007-20-9

Deskripsi belum tersedia.

Kategori:
Dental MaterialsDrug CarriersEnzyme Inhibitors +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 57916-92-4

Carbomer homopolymer type C is a high molecular polyanionic substance tested for antiulcerogenic activity.

Kategori:
Compounds used in a research, industrial, or household settingDental Cavity PreparationDental Materials +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbomycin DB11383
small molecule | CAS: 4564-87-8

Carbomycin, also called magnamycin, is crystalline macrolide antibiotic. This antibacterial is obtained from _Streptomyces halstedii_ and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. The structure of carbom…

Kategori:
Anti-Bacterial AgentsCytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A4 Inhibitors +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbon black DB11980
small molecule | CAS: 1333-86-4

Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.[A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the …

Kategori:
Complex MixturesParticulate MatterSmoke
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbon dioxide Approved DB09157
small molecule | CAS: 124-38-9

Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinder…

Kategori:
Carbon Compounds, InorganicGasesMedical Gases +7
Waktu ParuhData not found.
Vol. DistribusiData not found.
KlirensData not found.
Genetik -
Carbon monoxide Approved DB11588
small molecule | CAS: 630-08-0

Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that has a slightly lower density than air. It is toxic to hemoglobin utilizing animals (including humans), when encountered in concentrations above about 35 ppm, although it is also formed in n…

Kategori:
Carbon Compounds, InorganicDiagnostic AgentsGases +6
Target Protein:
Myoglobin
Waktu ParuhThe half-life of ca…
Vol. Distribusi-
Klirens-
Genetik -
Carbonate ion DB14531
small molecule | CAS: 3812-32-6

Deskripsi belum tersedia.

Kategori:
AlkaliesAnionsCarbon Compounds, Inorganic +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboplatin Approved DB00958
small molecule | CAS: 41575-94-4

Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.[A230523] Carboplatin was developed as an analog of [cisplatin] with red…

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Substrates +12
Target Protein:
DNA
Waktu ParuhThe distribution ha…
Vol. DistribusiThe apparent volume…
KlirensThe total body clea…
Genetik -
Carbopol 974P DB05384
small molecule | CAS: 151687-96-6

Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. It was under development by ReProtect LLC. It is a gel that may help both block the spread of…

Kategori:
Compounds used in a research, industrial, or household settingMacromolecular SubstancesPlastics +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboprost Approved DB19356
small molecule | CAS: 35700-23-3

Deskripsi belum tersedia.

Kategori:
Abortifacient AgentsAbortifacient Agents, NonsteroidalAutacoids +12
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboprost tromethamine Approved DB00429
small molecule | CAS: 58551-69-2

A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

Kategori:
Abortifacient AgentsAbortifacient Agents, NonsteroidalAlcohols +16
Target Protein:
Prostaglandin E2 receptor EP1 subtypeProstaglandin F2-alpha receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboquone DB13677
small molecule | CAS: 24279-91-2

Deskripsi belum tersedia.

Kategori:
Alkylating DrugsAntineoplastic AgentsAntineoplastic Agents, Alkylating +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carbovir DB17733
small molecule | CAS: 118353-05-2

Deskripsi belum tersedia.

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboxin Approved DB04657
small molecule | CAS: 5234-68-4

A systemic agricultural fungicide and seed treatment agent.

Kategori:
AgrochemicalsAmidesAmines +7
Target Protein:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 99519-84-3

Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntineoplastic Agents +8
Target Protein:
Muscarinic acetylcholine receptor M5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 33286-30-5

Deskripsi belum tersedia.

Kategori:
CarbohydratesDiterpenesGlycosides +1
Target Protein:
ADP/ATP translocase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 29161-67-9

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboxylic PRPP DB03942
small molecule

Deskripsi belum tersedia.

Target Protein:
Hypoxanthine-guanine-xanthine phosphoribosyltransferasePur operon repressorXanthine phosphoribosyltransferase +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Carboxymethylcellulose Approved DB11059
small molecule | CAS: 9000-11-7

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifie…

Kategori:
Anorexigenic Agents & Respiratory and CNS StimulantsArtificial TearsBulk-Forming Laxatives +9
Target Protein:
Solute carrier family 2, facilitated glucose transporter member 1
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cystathionine gamma-lyase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 3801–3850 dari 14494
Sebelumnya Halaman 77 / 290 Berikutnya