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6694

Total database: 17430
Struktur (SMILES)
4518 (67.5%)
Target
3751 (56.0%)
Genomik
81 (1.2%)
Referensi
6694 (100.0%)

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Hasil Pencarian (6694)

Halaman 77 / 134
Lactic acid Approved DB04398
small molecule | CAS: 50-21-5

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline tast…

Kategori:
Basic Ointments and ProtectantsGenito Urinary System and Sex HormonesGynecological Antiinfectives and Antiseptics +6
Target Protein:
Bifunctional protein PutANimA-related protein
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Lacticaseibacillus rhamnosus Approved DB19282
biotech

Deskripsi belum tersedia.

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Lactide, L- DB19115
small molecule | CAS: 4511-42-6

Lactide, L- is under investigation in clinical trial NCT05450471 (Effectiveness of Endonasal Polymeric Implant for Chronic Rhinosinusitis).

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Lactitol Approved DB12942
small molecule | CAS: 585-86-4

Lactitol, also known as 4-?-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose].[A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. [sucrose]).[A190912] Clinically…

Kategori:
AlcoholsAlimentary Tract and MetabolismCarbohydrates +15
Waktu ParuhThe average half-li…
Vol. DistribusiData regarding the …
KlirensData regarding the …
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Lactobacillus acidophilus Approved DB15823
biotech | CAS: 68333-16-4

Deskripsi belum tersedia.

Kategori:
CarbohydratesCarbon Compounds, InorganicCarbonates +7
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biotech

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Lactobacillus casei Approved DB16541
biotech | CAS: 68333-14-2

Deskripsi belum tersedia.

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biotech

Lactobacillus is a common bacteria found in the gut with Lactobacillus coryniformis K8 being originally isolated from artisan goat cheese.

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biotech

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small molecule

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Kategori:
Probiotics
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biotech

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biotech

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biotech

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biotech

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biotech

*Lactobacillus plantarum* is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. It is considered to be one of versatile species that carry out fermentative and me…

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biotech

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biotech

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small molecule | CAS: 96-82-2

Deskripsi belum tersedia.

Kategori:
CarbohydratesOligosaccharidesPolysaccharides
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Lactoferrin DB16555
biotech | CAS: 151186-19-5

Lactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).

Kategori:
Amino Acids, Peptides, and ProteinsAnimal Proteins, DietaryAnti-Infective Agents +22
Target Protein:
Tryptase alpha/beta-1
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Lactose Approved DB04465
small molecule | CAS: 63-42-3

A disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.

Kategori:
CarbohydratesCompounds used in a research, industrial, or household settingDiet, Food, and Nutrition +9
Target Protein:
Galectin-3SialidaseBeta-galactosidase +5
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Lactuca sativa whole Approved DB15604
biotech

Lactuca sativa whole allergenic extract is used in allergenic testing.

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Lactulose Approved DB00581
small molecule | CAS: 4618-18-2

Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite be…

Kategori:
Acidifying ActivityAlimentary Tract and MetabolismAmmonia Detoxicants +8
Target Protein:
Evolved beta-galactosidase subunit alpha
Waktu ParuhThe data regarding …
Vol. DistribusiNegligible amounts …
KlirensNegligible amounts …
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Laevulinic Acid DB02239
small molecule | CAS: 123-76-2

Deskripsi belum tersedia.

Target Protein:
Delta-aminolevulinic acid dehydratase
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Lamivudine Approved DB00709
small molecule | CAS: 134678-17-4

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +26
Target Protein:
Gag-Pol polyproteinReverse transcriptase/RNaseHDNA +1
Waktu Paruh5 to 7 hours (healt…
Vol. DistribusiApparent volume of …
Klirens* Renal clearance =…
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Lanabecestat DB14814
small molecule | CAS: 1383982-64-6

Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).

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Lancovutide DB05029
small molecule | CAS: 1391-36-2

Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is closely related to cinnamycin (Ro09-0198). It belongs to …

Kategori:
Amino Acids, Peptides, and ProteinsPeptides
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Lanicemine DB11889
small molecule | CAS: 153322-05-5

Lanicemine has been used in trials studying the treatment and basic science of Depression, Major Depressive Disorder, and Treatment Resistant Major Depressive Disorder.

Kategori:
AminesAntidepressive AgentsCentral Nervous System Depressants +2
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Lanolin Approved DB11112
small molecule | CAS: 8006-54-0

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointme…

Kategori:
Basic Ointments and ProtectantsCompounds used in a research, industrial, or household settingCosmetics +3
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Lanreotide Approved DB06791
small molecule | CAS: 108736-35-2

Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatost…

Kategori:
AcromegalyAmino Acids, Peptides, and ProteinsAntineoplastic Agents +22
Target Protein:
Somatostatin receptor type 2Somatostatin receptor type 5
Waktu ParuhHalf-life is approx…
Vol. DistribusiEstimated Volume of…
KlirensEstimated Clearance…
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Lansoprazole Approved DB00448
small molecule | CAS: 103577-45-3

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting…

Kategori:
Acid ReducersAlimentary Tract and MetabolismAnti-Ulcer Agents +39
Target Protein:
Potassium-transporting ATPase alpha chain 1Microtubule-associated protein tau
Gen Terkait:
CYP2C19 CYP2C19 ABCB1
Waktu ParuhOne source reports …
Vol. DistribusiThe apparent volume…
KlirensThe reported cleara…
Genetik 3 Varian
Lapachone DB11948
small molecule | CAS: 4707-32-8

Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.

Kategori:
Anti-Infective AgentsAnti-Retroviral AgentsAntiviral Agents +6
Target Protein:
DNA topoisomerase 1Retinol-binding protein 3
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Lapatinib Approved DB01259
small molecule | CAS: 231277-92-2

Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with t…

Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsCytochrome P-450 CYP2C19 Substrates +22
Target Protein:
Epidermal growth factor receptorEukaryotic elongation factor 2 kinaseReceptor tyrosine-protein kinase erbB-2
Gen Terkait:
HLA-DQA1 HLA-DRB1 HLA-DQB1 +1
Waktu ParuhSingle-dose termina…
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Genetik 4 Varian
Lapyrium Approved DB09376
small molecule | CAS: 109260-82-4

Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products [A19426]. It is commonly found formulated as lapyrium chloride.

Kategori:
Pyridines
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Larix occidentalis pollen Approved DB10914
biotech

Larix occidentalis pollen is the pollen of the Larix occidentalis plant. Larix occidentalis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Laronidase Approved DB00090
biotech | CAS: 210589-09-6

Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of th…

Kategori:
Alimentary Tract and MetabolismEnzymesEnzymes and Coenzymes +4
Target Protein:
Iduronic acid
Waktu Paruh1.5-3.6 hrs
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Lartesertib DB19045
small molecule | CAS: 2495096-26-7

Lartesertib is under investigation in clinical trial NCT06433219 (Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (Ddriver EOC 302)).

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Lasalocid DB11423
small molecule | CAS: 25999-31-9

Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiparasitic Agents +11
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Lasmiditan Approved DB11732
small molecule | CAS: 439239-90-4

Lasmiditan is an oral medication used in the termination of migraine headaches that was first approved for use in the United States in October 2019.[L9338,L9356] It was also approved by the European Commission on August 17, 2022.[L43997] Traditionally, the…

Kategori:
AmidesAnalgesicsAntidepressive Agents +17
Target Protein:
5-hydroxytryptamine receptor 1F
Waktu ParuhThe mean eliminatio…
Vol. DistribusiLasmiditan has been…
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Lasofoxifene Approved DB06202
small molecule | CAS: 180916-16-9

Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ER? and ER? with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatme…

Kategori:
Genito Urinary System and Sex HormonesNaphthalenesSelective Estrogen Receptor Modulators +1
Target Protein:
Fusion glycoprotein F0Estrogen receptorEstrogen receptor beta +1
Waktu ParuhElimination half-li…
Vol. DistribusiThe apparent volume…
KlirensThe apparent oral c…
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Latamoxef Approved DB04570
small molecule | CAS: 64952-97-2

Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins. It has been proposed especially for the meningitid…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +10
Target Protein:
Peptidoglycan synthase FtsIPenicillin-binding protein 3Penicillin-binding protein 1A +2
Waktu Paruh1.6 hours
Vol. Distribusi8.51 L
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Latanoprost Approved DB00654
small molecule | CAS: 130209-82-4

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment.[A184…

Kategori:
Antiglaucoma Preparations and MioticsAntihypertensive AgentsAutacoids +18
Target Protein:
Prostaglandin F2-alpha receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe systemic cleara…
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Latanoprost acid Approved DB19360
small molecule | CAS: 41639-83-2

Deskripsi belum tersedia.

Kategori:
AutacoidsBiological FactorsEicosanoids +6
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Latanoprostene bunod Approved DB11660
small molecule | CAS: 860005-21-6

Latanoprostene Bunod has been used in trials studying the treatment of Glaucoma, Ocular Hypertension, Open-Angle Glaucoma, Open Angle Glaucoma, and Intraocular Pressure. As of November 2, 2017 the FDA approved Bausch + Lomb's Vyzulta (latanoprostene bunod …

Kategori:
Antiglaucoma Preparations and MioticsAutacoidsBiological Factors +12
Target Protein:
Prostaglandin F2-alpha receptor
Waktu ParuhThe half-life after…
Vol. DistribusiUnfortunately there…
KlirensSince latanoprost a…
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Lauric acid Approved DB03017
small molecule | CAS: 143-07-7

Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with v…

Kategori:
Fatty AcidsLipids
Target Protein:
Toll-like receptor 4LactotransferrinPhospholipase A2, membrane associated +18
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small molecule | CAS: 112-16-3

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small molecule | CAS: 16610-63-2

Deskripsi belum tersedia.

Target Protein:
Farnesyl pyrophosphate synthaseGeranylgeranyl pyrophosphate synthase
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small molecule | CAS: 683-10-3

Deskripsi belum tersedia.

Kategori:
AminesOnium CompoundsQuaternary Ammonium Compounds +1
Target Protein:
AppA protein
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LAVA-051 DB18395
biotech

LAVA-051 is a humanized V?9V?2-T cell-engaging bispecific antibody.

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Lavender oil Approved DB14566
biotech | CAS: 8000-28-0

Deskripsi belum tersedia.

Kategori:
AngiospermsBiological ProductsComplex Mixtures +13
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LAX-101 DB05301
small molecule | CAS: 909712-41-0

LAX-101 treats hungtington’s disease, not just the symptoms but the disease itself. The active molecule in LAX-101 is Eicosapentaenoic Acid (EPA). All molecules of EPA are identical. The molecules of EPA found in LAX-101 are identical to the molecules of EPA …

Target Protein:
Phospholipase D1Caspase-1
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