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11778

Total database: 17430
Struktur (SMILES)
8554 (72.6%)
Target
6383 (54.2%)
Genomik
96 (0.8%)
Referensi
11778 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (11778)

Halaman 77 / 236
Cow milk Approved DB10543
biotech | CAS: 8049-98-7

Cow milk allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CP-122721 DB05421
small molecule | CAS: 145742-28-5

CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.

Target Protein:
Substance-P receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Sorbitol dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CP-271485 DB02118
small molecule | CAS: 35580-46-2

Deskripsi belum tersedia.

Target Protein:
Macrophage metalloelastase
Waktu Paruh-
Vol. Distribusi-
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CP-39,332 DB09193
small molecule | CAS: 61764-60-1

CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency. However, n…

Waktu Paruh-
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CP-547632 DB12962
small molecule | CAS: 252003-65-9

CP-547632 has been used in trials studying the treatment of Ovarian Cancer, Lung Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, and Fallopian Tube Cancer, among others.

Kategori:
AmidesSulfur Compounds
Target Protein:
Vascular endothelial growth factor receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CP-601927 DB12244
small molecule | CAS: 357425-02-6

CP-601,927 has been used in trials studying the basic science and treatment of Major Depressive Disorder.

Target Protein:
Neuronal acetylcholine receptor subunit alpha-4Neuronal acetylcholine receptor subunit beta-2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CP-609754 DB12640
small molecule | CAS: 1190094-64-4

LNK 754 has been investigated in Mild Alzheimer's Disease.

Kategori:
Heterocyclic Compounds, Fused-RingQuinolines
Waktu Paruh-
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CP-724714 DB12302
small molecule | CAS: 537705-08-1

CP-724,714 has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasm Metastasis.

Kategori:
Heterocyclic Compounds, Fused-RingReceptor, ErbB-2, antagonists & inhibitors
Target Protein:
Receptor tyrosine-protein kinase erbB-2
Waktu Paruh-
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CP-744809 DB07187
small molecule | CAS: 463976-07-0

Deskripsi belum tersedia.

Target Protein:
Aldo-keto reductase family 1 member B1
Waktu Paruh-
Vol. Distribusi-
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CP-778875 DB19211
small molecule | CAS: 866355-28-4

CP-778875 is under investigation in clinical trial NCT00326326 (Effect of CP-778,875 on HDL-C in Subjects With Abnormal Lipid Levels and Type 2 Diabetes.).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +2
Waktu Paruh-
Vol. Distribusi-
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CP-866087 DB12196
small molecule | CAS: 519052-02-9

CP-866,087 has been used in trials studying the treatment of Obesity, Alcoholism, and Sexual Dysfunction, Physiological.

Kategori:
Aza Compounds
Waktu Paruh-
Vol. Distribusi-
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CP-94707 DB07578
small molecule | CAS: 343250-05-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingHIV Reverse Transcriptase, antagonists & inhibitorsThiazoles
Target Protein:
Gag-Pol polyprotein
Waktu Paruh-
Vol. Distribusi-
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CP-96345 DB16744
small molecule | CAS: 132746-60-2

Deskripsi belum tersedia.

Kategori:
AnalgesicsAnalgesics, Non-NarcoticAnti-Inflammatory Agents +9
Target Protein:
Substance-P receptor
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CP1-1189 DB12311
small molecule | CAS: 183619-38-7

CPI-1189 has been used in trials studying the treatment of HIV Infections and AIDS Dementia Complex.

Kategori:
AlkanesHydrocarbons, Acyclic
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, liver form
Waktu Paruh-
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Genetik -
Cpad DB04071
small molecule

Deskripsi belum tersedia.

Target Protein:
Alcohol dehydrogenase 1C
Waktu Paruh-
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CPG 10101 DB05530
biotech | CAS: 957255-05-9

CPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials. It is a toll-like receptor 9 (TLR9) agonist with antiviral and immunomodulatory properties that could potentially influence chronic infection with HCV.

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleotidesOligonucleotides +1
Target Protein:
Toll-like receptor 9
Waktu Paruh-
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CPG-52852 DB12476
small molecule | CAS: 532959-63-0

852A has been used in trials studying the treatment of Melanoma, Neoplasms, Breast Cancer, Ovarian Cancer, and Cervical Cancer, among others.

Target Protein:
Toll-like receptor 7
Waktu Paruh-
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Genetik -
CPGJ602 DB17485
biotech

CPGJ602 is a recombinant anti-EGFR human-mouse chimeric monoclonal antibody.

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CPI-006 DB16488
biotech | CAS: 2451856-97-4

CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy. NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer). NCT04464395 and NCT047…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
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CPI-1205 DB14581
small molecule | CAS: 1621862-70-1

Potent and selective histone methyltransferase EZH2 inhibitor.

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-Ring
Target Protein:
Histone-lysine N-methyltransferase EZH2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CPO-107 DB18492
biotech

CPO-107 is a CD20-CD47 bispecific fusion protein

Waktu Paruh-
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Genetik -
small molecule | CAS: 640897-20-7

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +1
Target Protein:
4-aminobutyrate aminotransferase, mitochondrial
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CPZEN-45 DB18077
small molecule | CAS: 737759-36-3

Deskripsi belum tersedia.

Kategori:
Drugs for Treatment of Tuberculosis
Waktu Paruh-
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Genetik -
CR6086 DB16111
small molecule | CAS: 1417742-86-9

CR6086 is under investigation in clinical trial NCT03163966 (A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in Dmard-naïve Patients With Early Rheumatoid Arthritis).

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CR665 DB05155
small molecule | CAS: 228546-92-7

CR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that …

Kategori:
Amino Acids, Peptides, and ProteinsNerve Tissue ProteinsNeuropeptides +2
Target Protein:
Kappa-type opioid receptor
Waktu Paruh-
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Genetik -
CRA_10433 DB03173
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
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Genetik -
CRA_10656 DB04470
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_10762 DB02366
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_10972 DB02989
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_10991 DB01771
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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Genetik -
CRA_16847 DB02063
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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Genetik -
CRA_17312 DB02084
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
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Genetik -
CRA_17693 DB01741
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_1802 DB02875
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_9076 DB04215
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_9678 DB04563
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRA_9785 DB03595
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
CRD5 DB05587
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
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Creatine Approved DB00148
small molecule | CAS: 57-00-1

An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.

Kategori:
AmidinesAmino AcidsAmino Acids, Peptides, and Proteins +3
Target Protein:
Creatine kinase M-typeCreatine kinase U-type, mitochondrialCreatine kinase B-type +3
Waktu Paruh3 hours
Vol. Distribusi-
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Genetik -
Creatinine DB11846
small molecule | CAS: 60-27-5

Creatinine has been used in trials studying the treatment of Amyotrophic Lateral Sclerosis.

Kategori:
Imidazoles
Waktu Paruh-
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Genetik -
small molecule | CAS: 6903-79-3

COP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease. COP has been investigated for the treatment of Diabetic Retinopathy.

Kategori:
Cardiac Therapy
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Genetik -
Crefmirlimab DB17577
biotech | CAS: 2611099-93-3

Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.

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Crenezumab DB11959
biotech | CAS: 1095207-05-8

Crenezumab has been used in trials studying the treatment of Alzheimer's Disease.

Kategori:
Alzheimer Disease, drug therapyAmino Acids, Peptides, and ProteinsAntibodies +8
Waktu Paruh-
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Genetik -
Crenolanib DB11832
small molecule | CAS: 670220-88-9

Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.

Kategori:
Antineoplastic AgentsHeterocyclic Compounds, Fused-RingReceptor, Platelet-Derived Growth Factor alpha, antagonists & inhibitors +2
Target Protein:
Platelet-derived growth factor receptor alphaProto-oncogene tyrosine-protein kinase Src
Waktu Paruh-
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Cresol Approved DB11143
small molecule | CAS: 1319-77-3

Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including…

Kategori:
Benzene DerivativesDrugs that are Mainly Renally ExcretedPhenols +1
Waktu ParuhThere does not appe…
Vol. DistribusiOne study determine…
KlirensAs colonic microbia…
Genetik -
Cridanimod DB13674
small molecule | CAS: 38609-97-1

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicAntineoplastic and Immunomodulating AgentsHeterocyclic Compounds, Fused-Ring +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crinecerfont DB18518
small molecule | CAS: 752253-39-7

Deskripsi belum tersedia.

Kategori:
Sulfur Compounds
Target Protein:
Corticotropin-releasing factor receptor 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Crisaborole Approved DB05219
small molecule | CAS: 906673-24-3

Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reduci…

Kategori:
Agents for Dermatitis, Excluding CorticosteroidsAnti-Inflammatory AgentsCytochrome P-450 CYP2B6 Inhibitors +9
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B3',5'-cyclic-AMP phosphodiesterase 4C +1
Waktu Paruh-
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Genetik -
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