Hasil Filter

15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (15718)

Halaman 76 / 315
Biochanin A DB15334
small molecule | CAS: 491-80-5

Biochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).

Kategori:
Anticarcinogenic AgentsAntineoplastic AgentsBenzopyrans +12
Target Protein:
Steroid hormone receptor ERR1AromataseFatty acid synthase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biomed 101 DB05851
small molecule

Biomed 101 is investigated for use/treatment in adverse effects (chemotherapy) and renal cell carcinoma. Biomed 101 is a solid. Biomed 101 binds to the leukotriene B4 receptor, but does not affect interleukin-2 antitumor activity.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biomodulin T DB16529
biotech

Biomodulin T is a polypeptide fraction from bovine thymus with immunomodulatory effects.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biotin Approved DB00121
small molecule | CAS: 58-85-5

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

Kategori:
Alimentary Tract and MetabolismCoenzymesDiet, Food, and Nutrition +10
Target Protein:
Propionyl-CoA carboxylase beta chain, mitochondrialBiotin--protein ligaseMethylcrotonoyl-CoA carboxylase beta chain, mitochondrial +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BIOTINOL-5-AMP DB04651
small molecule

Deskripsi belum tersedia.

Target Protein:
Bifunctional ligase/repressor BirA
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bioymifi DB17493
small molecule | CAS: 1420071-30-2

Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi…

Kategori:
Acids, CarbocyclicHeterocyclic Compounds, Fused-RingImides +5
Target Protein:
Tumor necrosis factor receptor superfamily member 10B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biperiden Approved DB00810
small molecule | CAS: 514-65-8

A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induc…

Kategori:
Agents producing tachycardiaAnti-Dyskinesia AgentsAnti-Parkinson Drugs +18
Target Protein:
Muscarinic acetylcholine receptor M1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 792-74-5

Nissel has been investigated for the treatment of Chronic Liver Disease.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1133-63-7

Deskripsi belum tersedia.

Target Protein:
1,2-dihydroxynaphthalene dioxygenaseBiphenyl-2,3-diol 1,2-dioxygenaseBiphenyl-2,3-diol 1,2-dioxygenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biphenylol DB13734
small molecule | CAS: 1322-20-9

Deskripsi belum tersedia.

Kategori:
Antiseptics and DisinfectantsDermatologicalsPhenol and Derivatives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Birabresib DB15189
small molecule | CAS: 202590-98-5

Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).

Kategori:
AmidesAminesAnilides +2
Target Protein:
Bromodomain-containing protein 2Bromodomain-containing protein 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Birch bark extract Approved DB16536
small molecule | CAS: 84012-15-7

Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, [lupeol], [betulinic acid], oleanolic acid, and erythrodiol.[A249945] Birch bark extract is obtained…

Kategori:
Anti-Inflammatory AgentsAnti-inflammatory Agents, MiscellaneousBiological Products +7
Waktu ParuhThis pharmacokineti…
Vol. DistribusiThis pharmacokineti…
KlirensThis pharmacokineti…
Genetik -
Bird pepper Approved DB14262
biotech

Bird pepper is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biricodar DB04851
small molecule | CAS: 159997-94-1

The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).

Kategori:
P-glycoprotein inhibitors
Target Protein:
ATP-dependent translocase ABCB1ATP-binding cassette sub-family B member 5Multidrug resistance-associated protein 1 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Birinapant DB11782
small molecule | CAS: 1260251-31-7

Birinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML).

Kategori:
Amino Acids, Peptides, and ProteinsHeterocyclic Compounds, Fused-RingOligopeptides +1
Target Protein:
E3 ubiquitin-protein ligase XIAPBaculoviral IAP repeat-containing protein 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Biropepimut-S DB14816
biotech | CAS: 911338-45-9

Biropepimut-S is under investigation in clinical trial NCT02873819 (Safety and Efficacy Study of GL-0817 (With Cyclophosphamide) for the Prevention of Recurrence of Squamous Cell Carcinoma of the Oral Cavity).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Birtamimab DB16414
biotech | CAS: 1608108-91-3

Birtamimab is under investigation in clinical trial NCT02312206 (The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1282618-49-8

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Uncharacterized protein PA1000
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1Botulinum neurotoxin type B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 143-23-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Adenylate kinaseAdenylate kinaseAdenylate kinase +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Dephospho-CoA kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15209-14-0

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicDicarboxylic AcidsImides +1
Target Protein:
Azurin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serum amyloid P-component
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Serum amyloid P-component
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bis-Benzamidine DB02081
small molecule

Deskripsi belum tersedia.

Target Protein:
Serine protease 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bisacodyl Approved DB09020
small molecule | CAS: 603-50-9

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane…

Kategori:
Alimentary Tract and MetabolismBenzene DerivativesContact Laxatives +8
Target Protein:
Aquaporin-3Sodium/Potassium Transporting ATPase
Waktu ParuhData regarding the …
Vol. DistribusiData regarding the …
KlirensData regarding the …
Genetik -
Bisantrene DB17247
small molecule | CAS: 78186-34-2

Deskripsi belum tersedia.

Kategori:
Antibiotics, AntineoplasticAntineoplastic Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bisegliptin DB06127
small molecule | CAS: 862501-61-9

Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin …

Kategori:
Agents causing angioedemaBlood Glucose Lowering AgentsDPP-IV Inhibitors
Target Protein:
Dipeptidyl peptidase 4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
NAD(P)H dehydrogenase [quinone] 1FMN-dependent NADH-azoreductaseOxygen-insensitive NAD(P)H nitroreductase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 133052-90-1

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAnti-Inflammatory AgentsDicarboxylic Acids +5
Target Protein:
Mitogen-activated protein kinase 8Cyclin-dependent kinase 1Protein kinase C gamma type +16
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 125313-65-7

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAntiplatelet agentsDicarboxylic Acids +6
Target Protein:
Myotonin-protein kinase3-phosphoinositide-dependent protein kinase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bismuth cation DB14572
small molecule | CAS: 23713-46-4

Deskripsi belum tersedia.

Kategori:
AntacidsAnti-Infective AgentsAnti-Ulcer Agents +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bismuth oxide DB15929
small molecule | CAS: 1304-76-3

Deskripsi belum tersedia.

Kategori:
ElementsElements, RadioactiveIsotopes +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 5892-10-4

Deskripsi belum tersedia.

Kategori:
AlkaliesAnionsBismuth containing drugs +11
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bismuth subcitrate potassium Approved DB09275
small molecule | CAS: 880149-29-1

A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).

Kategori:
Alimentary Tract and MetabolismAnti-Infective AgentsAnti-Ulcer Agents +5
Target Protein:
ATP-dependent Clp protease ATP-binding subunit ClpX
Waktu ParuhThe elimination hal…
Vol. Distribusi-
KlirensThe rate of renal e…
Genetik -
Bismuth subgallate Approved DB13909
small molecule | CAS: 99-26-3

Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on …

Kategori:
Acids, CarbocyclicAntacids and AdsorbentsAnti-Infective Agents +12
Waktu ParuhThe bismuth compone…
Vol. DistribusiIn general, oral ad…
KlirensOn average, the blo…
Genetik -
Bismuth subnitrate Approved DB13209
small molecule | CAS: 1304-85-4

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent [A33012]. The use of bismuth substrate as an active …

Kategori:
Alimentary Tract and MetabolismAntacidsBismuth containing drugs +11
Waktu ParuhThe distribution ha…
Vol. DistribusiBismuth has been sh…
KlirensNo pharmacokinetic …
Genetik -
Bismuth subsalicylate Approved DB01294
small molecule | CAS: 14882-18-9

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation]. Each molecule of bismuth subsalicylate…

Kategori:
Acids, CarbocyclicAntacids and AdsorbentsAntidiarrheals +16
Waktu ParuhThe terminal half-l…
Vol. DistribusiThere is no informa…
KlirensThe renal clearance…
Genetik -
Bisoctrizole Approved DB11262
small molecule | CAS: 103597-45-1

Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212]. It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays. Bis…

Kategori:
Sunscreen Agents
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Bisoprolol Approved DB00612
small molecule | CAS: 66722-44-9

Bisoprolol is a cardioselective ?1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.[A1…

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Waktu ParuhA pharmacokinetic s…
Vol. DistribusiThe volume of distr…
KlirensTotal body clearanc…
Genetik -
Bisoxatin Approved DB09219
small molecule | CAS: 17692-24-9

Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine [L926]. It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon…

Kategori:
Alimentary Tract and MetabolismContact LaxativesDrugs for Constipation +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14008-48-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bisphenol A diglycidyl ether Approved DB14083
small molecule | CAS: 1675-54-3

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBisphenolsCarcinogens +8
Target Protein:
Cation channel sperm-associated protein 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bisphenol Z DB07485
small molecule | CAS: 843-55-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesCycloparaffinsPhenols
Target Protein:
Estrogen-related receptor gamma
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 3751–3800 dari 15718
Sebelumnya Halaman 76 / 315 Berikutnya