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13591

Total database: 17430
Struktur (SMILES)
10177 (74.9%)
Target
7625 (56.1%)
Genomik
104 (0.8%)
Referensi
13591 (100.0%)

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Hasil Pencarian (13591)

Halaman 73 / 272
Bismuth subnitrate Approved DB13209
small molecule | CAS: 1304-85-4

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent [A33012]. The use of bismuth substrate as an active …

Kategori:
Alimentary Tract and MetabolismAntacidsBismuth containing drugs +11
Waktu ParuhThe distribution ha…
Vol. DistribusiBismuth has been sh…
KlirensNo pharmacokinetic …
Genetik -
Bismuth subsalicylate Approved DB01294
small molecule | CAS: 14882-18-9

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation]. Each molecule of bismuth subsalicylate…

Kategori:
Acids, CarbocyclicAntacids and AdsorbentsAntidiarrheals +16
Waktu ParuhThe terminal half-l…
Vol. DistribusiThere is no informa…
KlirensThe renal clearance…
Genetik -
Bisoctrizole Approved DB11262
small molecule | CAS: 103597-45-1

Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212]. It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays. Bis…

Kategori:
Sunscreen Agents
Waktu ParuhNo pharmacokinetic …
Vol. DistribusiNo pharmacokinetic …
KlirensNo pharmacokinetic …
Genetik -
Bisoprolol Approved DB00612
small molecule | CAS: 66722-44-9

Bisoprolol is a cardioselective ?1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.[A1…

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +29
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Waktu ParuhA pharmacokinetic s…
Vol. DistribusiThe volume of distr…
KlirensTotal body clearanc…
Genetik -
Bisphenol A DB06973
small molecule | CAS: 80-05-7

Deskripsi belum tersedia.

Kategori:
Air PollutantsAir Pollutants, OccupationalAntioxidants +13
Target Protein:
Androgen receptorEstrogen receptor betaEstrogen-related receptor gamma
Waktu Paruh-
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Bisphenol A diglycidyl ether Approved DB14083
small molecule | CAS: 1675-54-3

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesBisphenolsCarcinogens +8
Target Protein:
Cation channel sperm-associated protein 1
Waktu Paruh-
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Bisphenol Z DB07485
small molecule | CAS: 843-55-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesCycloparaffinsPhenols
Target Protein:
Estrogen-related receptor gamma
Waktu Paruh-
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small molecule | CAS: 403717-06-6

Bisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).

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Bithionol Approved DB04813
small molecule | CAS: 97-18-7

Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24…

Kategori:
AnthelminticsAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +10
Target Protein:
Estrogen receptorCalpain-2 catalytic subunitEstrogen receptor beta +1
Waktu Paruh-
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Bitolterol DB00901
small molecule | CAS: 30392-40-6

Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +15
Target Protein:
Beta-3 adrenergic receptorBeta-2 adrenergic receptor
Waktu Paruh-
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Bivatuzumab DB06550
biotech

Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. [A31688,A31689]

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
CD44 antigen
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Bixalomer DB15200
small molecule | CAS: 851373-13-2

Bixalomer is under investigation in clinical trial NCT01115985 (A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers).

Kategori:
Amines
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biotech | CAS: 1977488-08-6

Bizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade Squamous Intraepitheli…

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +8
Waktu Paruh-
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Bizaxofusp DB17345
biotech | CAS: 1236019-35-4

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +5
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Bizelesin DB12352
small molecule | CAS: 129655-21-6

Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Alkylating DrugsAmidesAntibiotics, Antineoplastic +7
Waktu Paruh-
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BK-MDA DB12809
small molecule | CAS: 80535-73-5

BK-MDA has been used in trials studying the treatment of Bladder Exstrophy and Urinary Incontinence.

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Black cohosh DB13975
biotech

Black cohosh (_Actaea racemosa_ or _Cimicifuga racemosa_), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. Black…

Kategori:
AngiospermsBiological ProductsComplex Mixtures +21
Waktu ParuhApproximately 2h.[A…
Vol. Distribusi-
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Genetik -
biotech

Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]

Kategori:
AntiveninsPassively Acquired ImmunityVenom Neutralization
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Black-eyed pea Approved DB10663
biotech

Black-eyed pea allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
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Blarcamesine DB05592
small molecule | CAS: 195615-83-9

Deskripsi belum tersedia.

Target Protein:
Sigma non-opioid intracellular receptor 1Muscarinic acetylcholine receptor M1
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Bleomycin A2 DB19091
small molecule | CAS: 11116-31-7

Bleomycin A2 is under investigation in clinical trial NCT00026208 (Combination Chemotherapy Plus Low-dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma).

Kategori:
Amino Acids, Peptides, and ProteinsAngiogenesis InhibitorsAngiogenesis Modulating Agents +8
Waktu Paruh-
Vol. Distribusi-
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Bleomycin A6 DB12992
small molecule | CAS: 37293-17-7

Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic. This drug participated in clinical trials for the treatment of Squamous Cell Lung Ca…

Kategori:
Amino Acids, Peptides, and ProteinsCarbohydratesGlycoconjugates +2
Waktu Paruh-
Vol. Distribusi-
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Genetik -
Bleselumab DB15253
biotech | CAS: 1453067-91-8

Bleselumab is under investigation in clinical trial NCT02921789 (Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
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Bleximenib DB19328
small molecule | CAS: 2654081-35-1

Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia) and NCT05453903 (A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies)

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Blinatumomab Approved DB09052
biotech | CAS: 853426-35-4

Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an ant…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +17
Target Protein:
B-lymphocyte antigen CD19T-cell surface glycoprotein CD3 delta chain
Waktu ParuhBlinatumomab has a …
Vol. DistribusiBlinatumomab has a …
KlirensBlinatumomab has an…
Genetik -
Blisibimod DB12330
biotech | CAS: 1236126-45-6

Blisibimod has been used in trials studying the treatment of IgA Nephropathy, Microscopic Polyangiitis, Systemic Lupus Erythematosus, and Granulomatosis With Polyangiitis.

Kategori:
Amino Acids, Peptides, and ProteinsB-Cell Activating FactorImmunologic Factors +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Blonanserin DB09223
small molecule | CAS: 132810-10-7

Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. It offers improved tolerability as it lacks side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. As a second-generation (atypical) antipsychotic, it is s…

Kategori:
Antidepressive AgentsAntipsychotic AgentsAntipsychotic Agents (Second Generation [Atypical]) +13
Target Protein:
D(2) dopamine receptorD(3) dopamine receptor5-hydroxytryptamine receptor 2A
Waktu ParuhBlonanserin has a h…
Vol. DistribusiBlonanserin has a V…
KlirensBlonanserin has a c…
Genetik -
Blosozumab DB12560
biotech | CAS: 1132758-87-2

Blosozumab has been used in trials studying the basic science and treatment of Osteoporosis and Osteoporosis, Postmenopausal.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BLU-9931 DB17985
small molecule | CAS: 1538604-68-0

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicAcrylatesAmides +1
Waktu Paruh-
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Bluefish Approved DB10613
biotech

Bluefish allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
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Genetik -
BLX-883 DB05904
small molecule

BLX-883 is a form of alfa interferon developed by Biolex for the treatment of hepatitis viral C. Alfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide sales currently exceed $3 billion.

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BLXA4 DB12133
small molecule | CAS: 864516-86-9

BLXA4 has been used in trials studying the treatment of Gingival Inflammation.

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BLZ-945 DB16838
small molecule | CAS: 953769-46-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingPyridinesReceptor, Macrophage Colony-Stimulating Factor, antagonists & inhibitors +1
Target Protein:
Granulocyte colony-stimulating factor receptorMacrophage colony-stimulating factor 1 receptor
Waktu Paruh-
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Genetik -
BM-3103 DB18056
small molecule

Deskripsi belum tersedia.

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BMN-044 DB17003
biotech

Deskripsi belum tersedia.

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Genetik -
BMN-053 DB17008
biotech

Deskripsi belum tersedia.

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BMN-331 DB18324
biotech

Deskripsi belum tersedia.

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BMN-351 DB18186
biotech

BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).

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BMS-181156 DB02466
small molecule | CAS: 110368-35-9

Deskripsi belum tersedia.

Target Protein:
Retinoic acid receptor gamma
Waktu Paruh-
Vol. Distribusi-
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BMS-184476 DB12633
small molecule | CAS: 160237-25-2

BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
Waktu Paruh-
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BMS-188797 DB12619
small molecule | CAS: 172481-83-3

BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
CyclodecanesCycloparaffinsDiterpenes +1
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BMS-214662 DB12234
small molecule | CAS: 195987-41-8

BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute Promyelocytic Leukemia (M3)…

Kategori:
BenzazepinesHeterocyclic Compounds, Fused-Ring
Target Protein:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaProtein farnesyltransferase subunit beta
Waktu Paruh-
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BMS-275183 DB12144
small molecule | CAS: 355113-98-3

BMS-275183 has been used in trials studying the treatment of Tumors and Non-small Cell Lung Cancer.

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BMS-394136 DB12067
small molecule | CAS: 343246-73-1

BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.

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BMS-488043 DB05532
small molecule | CAS: 452296-83-2

BMS-488043 has been investigated as an anti-HIV agent.

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +6
Target Protein:
Free fatty acid receptor 4
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BMS-564929 DB07286
small molecule | CAS: 627530-84-1

BMS-564929 is an investigational therapeutic agent built to be a selective androgen receptor modulator (SARM). So far, it has been developed by Bristol-Myers Squibb for the symptomatic treatment of andropause.

Target Protein:
Androgen receptor
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BMS-582949 DB12696
small molecule | CAS: 623152-17-0

BMS-582949 has been investigated for the treatment of Psoriasis.

Kategori:
Mitogen-Activated Protein Kinase 14, antagonists & inhibitors
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BMS-599626 DB12318
small molecule | CAS: 714971-09-2

BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.

Kategori:
Acids, AcyclicErbB Receptors, antagonists & inhibitors
Target Protein:
Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2
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BMS-690514 DB11665
small molecule | CAS: 859853-30-8

BMS-690514 has been investigated for the treatment of Breast Cancer.

Kategori:
Carbon Radioisotopes
Target Protein:
Vascular endothelial growth factor receptor 2Epidermal growth factor receptorReceptor tyrosine-protein kinase erbB-2 +1
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BMS-741672 DB19004
small molecule | CAS: 1386991-77-0

BMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).

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Menampilkan 3601–3650 dari 13591
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