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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Hasil Pencarian (15718)

Halaman 73 / 315
Besifovir DB15671
small molecule | CAS: 441785-25-7

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingOrganophosphorus CompoundsPurines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 441785-26-8

Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. Besifovir dipivoxil is believed to inhibit viral proliferation…

Kategori:
Heterocyclic Compounds, Fused-RingOrganophosphorus CompoundsPurines +2
Target Protein:
Protein P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besilesomab Approved DB13979
biotech | CAS: 537694-98-7

Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Carcinoembryonic antigen
Waktu ParuhWhole blood concent…
Vol. DistribusiIn the besilesomab …
KlirensOnce administered i…
Genetik -
Beta carotene Approved DB06755
small molecule | CAS: 7235-40-7

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors.[T162] It is the most abundant form of carote…

Kategori:
Alimentary Tract and MetabolismAlkenesBiological Factors +20
Target Protein:
Free radicals
Waktu ParuhThe apparent half-l…
Vol. DistribusiNo pharmacokinetic …
KlirensThe clearance rate …
Genetik -
Beta vulgaris pollen Approved DB10837
biotech

Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 9051-97-2

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicCarbohydratesExperimental Unapproved Treatments for COVID-19 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arabinogalactan endo-beta-1,4-galactanase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1ProthrombinTyrosine--tRNA ligase, cytoplasmic
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 22951-96-8

Deskripsi belum tersedia.

Target Protein:
Phenylalanine-4-hydroxylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Alanine DB03107
small molecule | CAS: 107-95-9

beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBU…

Kategori:
AlanineAmino AcidsAmino Acids, Peptides, and Proteins
Target Protein:
Sodium- and chloride-dependent GABA transporter 3Pantothenate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 477-52-1

beta-Apopicropodophyllin is a component of the freshwater plant _Micranthemum umbrosum_.

Kategori:
Biological ProductsComplex MixturesPlant Extracts +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Ribose-5-phosphate isomerase A
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Pyruvate kinase PKLRGlycerol kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7660-25-5

Deskripsi belum tersedia.

Target Protein:
Fucose-binding lectin PA-IIL
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-D-fucose DB04062
small molecule | CAS: 28161-52-6

Deskripsi belum tersedia.

Target Protein:
L-arabinose-binding periplasmic proteinArabinose operon regulatory protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesOligosaccharidesPolysaccharides
Target Protein:
Arabinogalactan endo-beta-1,4-galactanase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 18968-14-4

Deskripsi belum tersedia.

Target Protein:
AlgQ1AlgQ2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14196-86-2

Deskripsi belum tersedia.

Target Protein:
Galectin-7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
6-phospho-beta-galactosidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle form
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beta-D-Glucose DB02379
small molecule | CAS: 492-61-5

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Kategori:
CarbohydratesGlucosidesGlycosides +2
Target Protein:
Neutral alpha-glucosidase ABNeutral alpha-glucosidase CHexokinase-4 +91
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15209-12-8

Deskripsi belum tersedia.

Target Protein:
Glucose-6-phosphate 1-dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 23018-83-9

Deskripsi belum tersedia.

Kategori:
CarbohydratesHexosesMonosaccharides
Target Protein:
Hyaluronate lyaseChondroitinase-ACXylan alpha-1,2-glucuronidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Escin DB15774
small molecule | CAS: 26339-90-2

Deskripsi belum tersedia.

Kategori:
CarbohydratesCardiovascular AgentsGlycosides +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 20790-72-1

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, BasicAmino Acids, Diamino +2
Target Protein:
Mannan-binding lectin serine protease 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 300-85-6

Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236 (completed for type 1 diabetes), and NCT0558104…

Kategori:
Acids, AcyclicButyratesExperimental Unapproved Treatments for COVID-19 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 78995-10-5

Deskripsi belum tersedia.

Kategori:
Piperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 625-08-1

beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.).

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 24915-04-6

Deskripsi belum tersedia.

Kategori:
AlkaloidsAntiarrhythmic agentsCardiovascular Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-L-fucose DB03283
small molecule | CAS: 13224-93-6

Deskripsi belum tersedia.

Target Protein:
AcetylcholinesteraseAlpha-L-fucosidase, putative
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Mannobiose DB01687
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Histo-blood group ABO system transferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6051-87-2

?-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.

Kategori:
BenzoflavonesBenzopyransChromones +7
Target Protein:
Estrogen receptorSteroid hormone receptor ERR1COUP transcription factor 1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Pinene DB15574
small molecule | CAS: 127-91-3

Deskripsi belum tersedia.

Kategori:
Bridged-Ring CompoundsMonoterpenesTerpenes
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Sitosterol DB14038
small molecule | CAS: 83-46-5

Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.

Kategori:
Biological FactorsCholestanesCholestenes +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 17199-59-6

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betahistine Approved DB06698
small molecule | CAS: 5638-76-6

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-l…

Kategori:
Antivertigo PreparationsHistamine AgentsHistamine Agonists +7
Target Protein:
Histamine H1 receptorHistamine H3 receptor
Waktu ParuhThe half-life of be…
Vol. DistribusiIn a pharmacokineti…
Klirens-
Genetik -
Betaine Approved DB06756
small molecule | CAS: 107-43-7

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252…

Kategori:
Acid PreparationsAlimentary Tract and MetabolismAmines +12
Target Protein:
Betaine--homocysteine S-methyltransferase 1
Waktu ParuhIn healthy voluntee…
Vol. DistribusiBased on a study do…
KlirensBased on a study do…
Genetik -
small molecule | CAS: 7418-61-3

Deskripsi belum tersedia.

Kategori:
AminesOnium CompoundsQuaternary Ammonium Compounds +1
Target Protein:
Gamma-aminobutyraldehyde dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betameprodine DB01552
small molecule | CAS: 468-50-8

Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine).…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betamethasone Approved DB00443
small molecule | CAS: 378-44-9

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmu…

Kategori:
Adrenal Cortex HormonesAdrenalsAgents Causing Muscle Toxicity +52
Target Protein:
Glucocorticoid receptor
Waktu ParuhIn a study that inc…
Vol. DistribusiIn a study that inc…
KlirensIn a study that inc…
Genetik -
Betamethasone phosphate Approved DB14669
small molecule | CAS: 360-63-4

Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone] to agonize glucocorticoid receptors.[L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium and water…

Kategori:
Adrenal Cortex HormonesCorticosteroidsCytochrome P-450 CYP3A Inducers +20
Target Protein:
Glucocorticoid receptorAnnexin A1
Waktu ParuhThe half life of be…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of be…
Genetik -
Betaprodine DB01473
small molecule | CAS: 468-59-7

An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures.…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betaxolol Approved DB00195
small molecule | CAS: 63659-18-7

A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-1 Receptor Antagonists +28
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptor
Waktu Paruh14-22 hours
Vol. Distribusi-
Klirens-
Genetik -
Betazole Approved DB00272
small molecule | CAS: 105-20-4

A histamine H2 agonist used clinically to test gastric secretory function.

Kategori:
Diagnostic AgentsGastrointestinal AgentsHistamine Agents +4
Target Protein:
Histamine H2 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bethanechol Approved DB01019
small molecule | CAS: 674-38-4

Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympat…

Kategori:
Acids, AcyclicAminesAmmonium Compounds +16
Target Protein:
Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M5Muscarinic acetylcholine receptor M1 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bethanidine Approved DB00217
small molecule | CAS: 55-73-2

A guanidinium antihypertensive agent that acts by blocking adrenergic transmission.

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-2 Receptor Agonists +13
Target Protein:
Beta-1 adrenergic receptorATP-sensitive inward rectifier potassium channel 1Alpha-2 adrenergic receptors +1
Waktu Paruh9 hours (range 7 to…
Vol. Distribusi-
Klirens-
Genetik -
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