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15718

Total database: 17430
Struktur (SMILES)
10762 (68.5%)
Target
7957 (50.6%)
Genomik
112 (0.7%)
Referensi
15718 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (15718)

Halaman 72 / 315
Benzophenone DB01878
small molecule | CAS: 119-61-9

Benzophenone is the organic compound. Substituted benzophenones such as oxybenzone and dioxybenzone are used in sunscreen.

Kategori:
Benzene DerivativesDermatologicalsKetones +2
Target Protein:
Estrogen receptorEstrogen receptor beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoxonium DB13565
small molecule | CAS: 23884-64-2

Deskripsi belum tersedia.

Kategori:
Alimentary Tract and MetabolismAminesAntiinfectives and Antiseptics for Local Oral Treatment +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoyl peroxide Approved DB09096
small molecule | CAS: 94-36-0

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [a…

Kategori:
Acids, CarbocyclicAnti-Acne PreparationsAnti-Acne Preparations for Topical Use +5
Target Protein:
CatalaseGlutathione peroxidaseAntizyme inhibitor 2 +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoylecgonine DB01515
small molecule | CAS: 519-09-5

Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the…

Kategori:
AlkaloidsAza CompoundsAzabicyclo Compounds +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 611-73-4

Deskripsi belum tersedia.

Kategori:
Acids, AldehydicAcids, CarbocyclicHydroxy Acids
Target Protein:
2-Hydroxyacid oxidase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 18481-26-0

Deskripsi belum tersedia.

Kategori:
PyrimidinesSulfur CompoundsThiazoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzoylpas DB19382
small molecule | CAS: 13898-58-3

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzphetamine Approved DB00865
small molecule | CAS: 156-08-1

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +28
Target Protein:
Synaptic vesicular amine transporterAlpha-2A adrenergic receptorAlpha-1A adrenergic receptor +1
Waktu Paruh16 to 31 hours
Vol. Distribusi-
Klirens-
Genetik -
Benzquinamide DB00767
small molecule | CAS: 63-12-7

Benzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine …

Kategori:
Agents producing tachycardiaAnticholinergic AgentsHeterocyclic Compounds, Fused-Ring +4
Target Protein:
Histamine H1 receptorMuscarinic acetylcholine receptor M4Muscarinic acetylcholine receptor M1 +3
Waktu Paruh1-1.6 hours (for al…
Vol. Distribusi-
Klirens-
Genetik -
Benzthiazide Approved DB00562
small molecule | CAS: 91-33-8

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium…

Kategori:
DiureticsGenito Urinary System and Sex HormonesGynecological Antiinfectives and Antiseptics +8
Target Protein:
Solute carrier family 12 member 3Carbonic anhydraseCarbonic anhydrase 2 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Collagenase 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl alcohol Approved DB06770
small molecule | CAS: 100-51-6

Deskripsi belum tersedia.

Kategori:
AlcoholsAnestheticsAnesthetics, Local +18
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl benzoate Approved DB00676
small molecule | CAS: 120-51-4

Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl b…

Kategori:
AcaricidesAcids, CarbocyclicAgrochemicals +8
Target Protein:
Hormone-sensitive lipase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzyl formate DB04569
small molecule | CAS: 104-57-4

Deskripsi belum tersedia.

Kategori:
Acids, Acyclic
Target Protein:
Thermolysin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 622-78-6

Deskripsi belum tersedia.

Kategori:
IsocyanatesSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Cathepsin FCruzipain
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 94-44-0

Deskripsi belum tersedia.

Kategori:
Pyridines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylamine DB02464
small molecule | CAS: 100-46-9

Deskripsi belum tersedia.

Kategori:
AminesBenzene DerivativesBenzyl Compounds
Target Protein:
Serine protease 1Trypsin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylfentanyl DB09182
small molecule | CAS: 1474-02-8

Benzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it was removed from the list after it was found to have minimal opioid activity. Benzylfentan…

Kategori:
Piperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylmorphine DB01573
small molecule | CAS: 14297-87-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylparaben Approved DB14176
small molecule | CAS: 94-18-8

Benzylparaben is used in allergenic testing.

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzylpenicillin Approved DB01053
small molecule | CAS: 61-33-6

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may al…

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +18
Target Protein:
Peptidoglycan synthase FtsIPenicillin-binding protein 1APenicillin-binding protein 1B +5
Waktu ParuhIn adults with norm…
Vol. Distribusi0.53–0.67 L/kg in a…
Klirens560ml/min in health…
Genetik -
Benzylpenicilloyl polylysine Approved DB00895
small molecule | CAS: 31855-75-1

Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluati…

Kategori:
AcetamidesAmidesAnti-Bacterial Agents +9
Target Protein:
High affinity immunoglobulin epsilon receptor subunit gammaHigh affinity immunoglobulin epsilon receptor subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 100-87-8

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonatesAlkanesulfonic Acids +4
Target Protein:
ChymaseSubtilisin BPN'Sigma factor SigB regulation protein RsbQ +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 6336-50-1

Deskripsi belum tersedia.

Kategori:
Antithyroid agentsPyrimidinesPyrimidinones +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 627861-07-8

Beperminogene perplasmid is under investigation in clinical trial NCT02144610 (Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia).

Kategori:
Vasoprotectives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bephenium DB13462
small molecule | CAS: 7181-73-9

Deskripsi belum tersedia.

Kategori:
AnthelminticsAntinematodal AgentsAntiparasitic Agents +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepotastine Approved DB04890
small molecule | CAS: 125602-71-3

Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe…

Kategori:
Anti-Allergic AgentsDrugs that are Mainly Renally ExcretedHistamine Antagonists +2
Target Protein:
Histamine H1 receptor
Waktu ParuhElimination half li…
Vol. Distribusi-
Klirens-
Genetik -
Bepranemab DB17945
biotech | CAS: 2244960-75-4

Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepridil Approved DB01244
small molecule | CAS: 64706-54-3

A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a cal…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +20
Target Protein:
Voltage-dependent P/Q-type calcium channel subunit alpha-1AVoltage-dependent T-type calcium channel subunit alpha-1HVoltage-dependent calcium channel subunit alpha-2/delta-2 +7
Waktu Paruh24-50 hours
Vol. Distribusi-
Klirens-
Genetik -
Beractant Approved DB06761
biotech | CAS: 108778-82-1

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral li…

Kategori:
Alveolar Surface Tension ReductionBradycardia-Causing AgentsComplex Mixtures +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berbamine DB18146
small molecule | CAS: 478-61-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAnalgesicsAnalgesics, Non-Narcotic +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berberine Approved DB04115
small molecule | CAS: 2086-83-1

An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.

Kategori:
AlkaloidsBenzylisoquinolinesBerberine Alkaloids +1
Target Protein:
Telomerase reverse transcriptaseBaculoviral IAP repeat-containing protein 5HTH-type transcriptional regulator QacR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1868138-66-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berdazimer Approved DB18712
small molecule

Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate…

Kategori:
Macromolecular SubstancesOrganosilicon CompoundsPolymers +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beremagene geperpavec Approved DB17831
biotech | CAS: 2241888-62-8

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolys…

Kategori:
Administration, TopicalCellular and Gene TherapyCicatrizants +2
Waktu ParuhThere is no informa…
Vol. DistribusiThere is no informa…
KlirensThere is no informa…
Genetik -
Bergamot oil DB14335
biotech | CAS: 8007-75-8

Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bergapten DB12216
small molecule | CAS: 484-20-8

Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).

Kategori:
Anti-Inflammatory AgentsAntipsoriaticsAntipsoriatics for Systemic Use +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berkelium DB12993
small molecule | CAS: 7440-40-6

Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP-544C).

Kategori:
Actinoid Series ElementsElementsElements, Radioactive +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bermekimab DB14947
biotech | CAS: 1401965-15-8

Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beroctocog alfa Approved DB14473
biotech | CAS: 9001-27-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berotralstat Approved DB15982
small molecule | CAS: 1809010-50-1

Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE).[L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that pro…

Kategori:
BCRP/ABCG2 SubstratesBlood and Blood Forming OrgansCytochrome P-450 CYP2D6 Inhibitors +16
Target Protein:
Plasma kallikrein
Waktu ParuhFollowing a single …
Vol. DistribusiThe blood to plasma…
KlirensThere is no informa…
Genetik -
Bersacapavir DB19035
small molecule | CAS: 1638266-40-6

Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

Kategori:
Anti-Infective AgentsAntiviral Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersanlimab DB17377
biotech | CAS: 1987854-08-9

Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersiporocin DB18017
small molecule | CAS: 2241808-52-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bertilimumab DB05429
biotech

Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.

Target Protein:
Eotaxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berubicin DB17149
small molecule | CAS: 677017-23-1

Deskripsi belum tersedia.

Kategori:
Aminoglycoside AntibacterialsAnti-Bacterial AgentsCarbohydrates +2
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berzosertib DB11794
small molecule | CAS: 1232416-25-9

Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

Target Protein:
Serine/threonine-protein kinase ATR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besifloxacin Approved DB06771
small molecule | CAS: 141388-76-3

Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +16
Target Protein:
DNA topoisomerase 4 subunit ADNA gyrase subunit BDNA gyrase subunit A +3
Waktu ParuhThe average elimina…
Vol. DistribusiNot absorbed into t…
KlirensN/A
Genetik -
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