Hasil Filter

14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
Referensi
14494 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (14494)

Halaman 70 / 290
biotech

Deskripsi belum tersedia.

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human resp…

Kategori:
Actively Acquired ImmunityBiological ProductsComplex Mixtures +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Boric acid Approved DB11326
small molecule | CAS: 10043-35-3

Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmet…

Kategori:
AcidsAcids, NoncarboxylicAgrochemicals +12
Waktu ParuhAccording to human …
Vol. DistribusiVolume of distribut…
KlirensA case report of ac…
Genetik -
Borneol DB11288
small molecule | CAS: 507-70-0

Deskripsi belum tersedia.

Kategori:
Bicyclic MonoterpenesBridged-Ring CompoundsMonoterpenes +3
Target Protein:
Transient receptor potential cation channel subfamily V member 3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bornyl acetate DB14665
small molecule | CAS: 76-49-3

Deskripsi belum tersedia.

Kategori:
Bicyclic MonoterpenesBridged-Ring CompoundsMonoterpenes +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Borocaptate DB17408
small molecule

Deskripsi belum tersedia.

Kategori:
BoranesBoron CompoundsBoron Neutron Capture Therapy +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Boron DB11203
small molecule | CAS: 7440-42-8

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however …

Kategori:
Diet, Food, and NutritionElementsFood +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bortezomib Approved DB00188
small molecule | CAS: 179324-69-7

Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.[A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reve…

Kategori:
AcidsAcids, NoncarboxylicAntineoplastic Agents +36
Target Protein:
Proteasome subunit beta type-5Serine protease 1Proteasome subunit beta type-1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean distributi…
KlirensFollowing the admin…
Genetik -
Bortezomib D-mannitol Approved DB16741
small molecule | CAS: 444576-08-3

Deskripsi belum tersedia.

Kategori:
Antineoplastic AgentsProteasome Inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bos taurus dander Approved DB11020
biotech

Bos taurus dander allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Bos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Complex MixturesGallstones
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bos taurus hair Approved DB10856
biotech

Bos taurus hair is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bos taurus skin Approved DB10406
biotech

Bos taurus skin or pelt is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BOS172722 DB15498
small molecule | CAS: 1578245-44-9

BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent.[A187123] Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the gro…

Target Protein:
Dual specificity protein kinase TTK
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bosakitug DB19101
biotech | CAS: 2762183-23-1

Bosakitug (BSI-045B) is under investigation in clinical trial NCT05932654 (POC Study to Evaluate BSI-045B Monotherapy and BSI-045B Add-on Therapy With Dupilumab in Atopic Dermatitis).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Boscalid Approved DB12792
small molecule | CAS: 188425-85-6

Boscalid has been investigated for the treatment of OSDI, Glaucoma, Staining, Schirmers, and Disease Severity, among others.

Kategori:
Benzene DerivativesNicotinic AcidsPyridines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bosentan Approved DB00559
small molecule | CAS: 147536-97-8

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the…

Kategori:
AmidesAntihypertensive AgentsAntihypertensives for Pulmonary Arterial Hypertension +24
Target Protein:
Endothelin receptor type BEndothelin-1 receptor
Waktu ParuhTerminal eliminatio…
Vol. Distribusi* 18 L
Klirens* 4 L/h [patients w…
Genetik -
Boserolimab DB17452
biotech | CAS: 2444297-08-7

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bosutinib Approved DB06616
small molecule | CAS: 380843-75-4

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hall…

Kategori:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +22
Target Protein:
Tyrosine-protein kinase ABL1Tyrosine-protein kinase LynProto-oncogene tyrosine-protein kinase Src +8
Waktu ParuhThe mean (SD) bosut…
Vol. DistribusiThe mean (SD) appar…
KlirensThe mean (SD) appar…
Genetik -
biotech | CAS: 2417551-39-2

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Botensilimab DB16651
biotech | CAS: 2408310-37-0

Botensilimab is under investigation in clinical trial NCT03860272 (Fc-engineered Anti-ctla-4 Monoclonal Antibody in Advanced Cancer).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Botrytis cinerea Approved DB10428
biotech

Botrytis cinerea is a fungus which can provoke allergic reactions. Botrytis cinerea extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Botulinum toxin type A Approved DB00083
biotech | CAS: 93384-43-1

In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use.[A231824] With a wide variety of applications and favourable safety profile, Botulinum toxin A injecti…

Kategori:
Acetylcholine Release InhibitorsAgents that produce neuromuscular block (indirect)Amino Acids, Peptides, and Proteins +29
Target Protein:
Synaptosomal-associated protein 25Rho-related GTP-binding protein RhoB
Waktu ParuhThere is no readily…
Vol. DistribusiThere are extremely…
KlirensClearance informati…
Genetik -
Botulinum toxin type B Approved DB00042
biotech | CAS: 93384-44-2

Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and …

Kategori:
Acetylcholine Release InhibitorsAgents that produce neuromuscular block (indirect)Amino Acids, Peptides, and Proteins +28
Target Protein:
Vesicle-associated membrane protein 2Vesicle-associated membrane protein 1Synaptotagmin-2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Botulinum toxin type e is under investigation in clinical trial NCT03193593 (Study to Evaluate EB-001 in Reducing Musculoskeletal Pain).

Kategori:
Amino Acids, Peptides, and ProteinsBacterial ProteinsBacterial Toxins +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bouteloua gracilis pollen Approved DB10715
biotech

Bouteloua gracilis pollen is the pollen of the Bouteloua gracilis plant. Bouteloua gracilis pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityGrass Pollen Allergen ExtractsIncreased Histamine Release +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1383710-57-3

Bovhyaluronidase azoximer is under investigation in clinical trial NCT06458543 (Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bovine type I collagen Approved DB10771
biotech | CAS: 9050-08-2

Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration [L2481]. Often combined with other ingredie…

Kategori:
Allogeneic Cultured Cell Scaffold
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BP-14979 DB16302
small molecule | CAS: 1000036-77-0

BP-14979 is under investigation in clinical trial NCT01785147 (Efficacy and Safety of BP1.4979 in Smoking Cessation).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BPC-157 DB11882
small molecule | CAS: 137525-51-0

Bepecin is under investigation in clinical trial NCT02637284 (PCO-02 - Safety and Pharmacokinetics Trial).

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Ulcer AgentsGastrointestinal Agents +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BPH-608 DB07404
small molecule

Deskripsi belum tersedia.

Target Protein:
Farnesyl pyrophosphate synthaseDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BPI-3016 DB15158
biotech

BPI-3016 is under investigation in clinical trial NCT03188848 (Dose Escalating Study of BPI-3016 in Healthy Subjects).

Kategori:
Amino Acids, Peptides, and ProteinsGastrointestinal HormonesGlucagon-Like Peptides +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BQ-123 DB12054
small molecule | CAS: 136553-81-6

BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.

Kategori:
Amino Acids, Peptides, and ProteinsAntihypertensive AgentsCardiovascular Agents +2
Target Protein:
Endothelin-1 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BQ-788 DB17984
small molecule | CAS: 156161-89-6

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntihypertensive AgentsCardiovascular Agents +3
Target Protein:
Endothelin receptor type B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BR-007 DB18408
small molecule | CAS: 2409546-40-1

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
BR101801 DB17387
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bradanicline DB06090
small molecule | CAS: 639489-84-2

Bradanicline, a novel small molecule that modulates the activity of the neuronal nicotinic receptor (NNR) subtype known as alpha7(?7). Bradanicline belongs to a new class of drugs for the treatment of central nervous system diseases and disorders.

Kategori:
Heterocyclic Compounds, Fused-RingReceptors, Nicotinic
Target Protein:
Neuronal acetylcholine receptor subunit alpha-7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bradykinin DB12126
small molecule | CAS: 58-82-2

Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.

Kategori:
Amino Acids, Peptides, and ProteinsAutacoidsBiological Factors +11
Target Protein:
B2 bradykinin receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Branaplam DB14918
small molecule | CAS: 1562338-42-4

Branaplam is under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)).

Target Protein:
Survival motor neuron protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Branebrutinib DB15347
small molecule | CAS: 1912445-55-6

Branebrutinib is under investigation in clinical trial NCT02705989 (Safety, Tolerability and Relative Bioavailability Study of BMS-986195 in Healthy Subjects).

Kategori:
Enzyme InhibitorsHeterocyclic Compounds, Fused-RingProtein Kinase Inhibitors
Target Protein:
Tyrosine-protein kinase BTK
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Brasofensine DB04857
small molecule | CAS: 171655-91-7

Brasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K. In November 2001, NeuroSearch confirmed that the drug's development…

Kategori:
AminesHeterocyclic Compounds, Fused-RingHydroxylamines
Target Protein:
Sodium-dependent serotonin transporterD(2) dopamine receptor
Waktu ParuhPlasma terminal eli…
Vol. Distribusi-
Klirens-
Genetik -
Brassica rapa pollen Approved DB10942
biotech

Brassica rapa pollen is the pollen of the Brassica rapa plant. Brassica rapa pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Brazikumab DB16115
biotech | CAS: 1610353-18-8

Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Brazil nut Approved DB10510
biotech

Brazil nut allergenic extract is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseNon-Standardized Food Allergenic Extract
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Brecanavir DB04887
small molecule | CAS: 313682-08-5

Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. In July 2006, Vertex indicated that it expected GSK to initiate phase III trials of the drug in 2007. In Decembe…

Kategori:
Acids, AcyclicDioxolesHeterocyclic Compounds, Fused-Ring
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 3451–3500 dari 14494
Sebelumnya Halaman 70 / 290 Berikutnya