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14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
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14494 (100.0%)

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Halaman 69 / 290
BMS-813160 DB16240
small molecule | CAS: 1286279-29-5

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).

Kategori:
Cardiovascular Agents
Target Protein:
C-C chemokine receptor type 2C-C chemokine receptor type 5
Waktu Paruh-
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BMS-817399 DB14941
small molecule | CAS: 1202400-18-7

BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).

Kategori:
AmidesAmino AcidsAmino Acids, Branched-Chain +1
Target Protein:
C-C chemokine receptor type 1
Waktu Paruh-
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BMS-830216 DB14787
small molecule | CAS: 1197420-06-6

BMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).

Target Protein:
Melanin-concentrating hormone receptor 1
Waktu Paruh-
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BMS-863233 DB12357
small molecule | CAS: 1169558-38-6

BMS-863233 has been investigated for the treatment of Refractory Hematologic Cancer.

Target Protein:
Cell division cycle 7-related protein kinase
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BMS-908662 DB12854
small molecule | CAS: 870603-16-0

BMS-908662 has been used in trials studying the treatment of Melanoma and Colorectal Cancer.

Target Protein:
Serine/threonine-protein kinase B-raf
Waktu Paruh-
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BMS-911543 DB12591
small molecule | CAS: 1271022-90-2

BMS-911543 has been used in trials studying the treatment of Cancer.

Kategori:
Heterocyclic Compounds, Fused-RingJanus Kinase 2, antagonists & inhibitorsJanus Kinases, antagonists & inhibitors
Target Protein:
Tyrosine-protein kinase JAK2
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BMS-919373 DB15047
small molecule | CAS: 1272353-82-8

BMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).

Target Protein:
Potassium voltage-gated channel subfamily A member 5
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BMS-929075 DB14950
small molecule | CAS: 1217338-97-0

BMS-929075 is under investigation in clinical trial NCT01525212 (Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients).

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BMS-955176 DB15193
small molecule | CAS: 1392312-45-6

BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +2
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BMS-986012 DB14831
biotech | CAS: 1894272-37-7

BMS-986012 is a human antifucosyl-GM1 antibody. It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).

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BMS-986020 DB14948
small molecule | CAS: 1257213-50-5

BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers).

Target Protein:
Lysophosphatidic acid receptor 1
Waktu Paruh-
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BMS-986094 DB11966
small molecule | CAS: 1234490-83-5

INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.

Kategori:
Guanine NucleotidesHeterocyclic Compounds, Fused-RingNucleic Acids, Nucleotides, and Nucleosides +4
Target Protein:
Genome polyprotein
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BMS-986104 DB15214
small molecule | CAS: 1622180-31-7

BMS-986104 is under investigation in clinical trial NCT02211469 (A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects).

Target Protein:
Sphingosine 1-phosphate receptor 1
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BMS-986115 DB13126
small molecule | CAS: 1584647-27-7

BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.

Kategori:
BenzazepinesEnzyme InhibitorsGamma Secretase Inhibitors and Modulators +1
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BMS-986141 DB14942
small molecule | CAS: 1478711-48-6

BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Target Protein:
PRKC apoptosis WT1 regulator protein
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BMS-986142 DB15291
small molecule | CAS: 1643368-58-4

BMS-986142 is under investigation in clinical trial NCT02880670 (Pharmacokinetics and Metabolism Study of Radiolabeled BMS-986142 in Healthy Male Subjects).

Target Protein:
Tyrosine-protein kinase BTK
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BMS-986158 DB15435
small molecule | CAS: 1800340-40-2

BMS-986158 is under investigation in clinical trial NCT02419417 (Study of BMS-986158 in Subjects With Select Advanced Cancers).

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BMS-986251 DB19007
small molecule | CAS: 2041841-30-7

BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).

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BMS-986278 DB18011
small molecule | CAS: 2170126-74-4

Deskripsi belum tersedia.

Target Protein:
Lysophosphatidic acid receptor 1
Waktu Paruh-
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BMSC-0013 DB02474
small molecule

Deskripsi belum tersedia.

Target Protein:
Cholera enterotoxin subunit B
Waktu Paruh-
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BN-201 DB18295
small molecule | CAS: 1361200-34-1

Deskripsi belum tersedia.

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BN104 DB18172
small molecule

Deskripsi belum tersedia.

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biotech

BN?Brachyury vaccine is a novel prime?boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)?Brachyury booster vaccine.[A255173]

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BNC-210 DB19048
small molecule | CAS: 1020634-41-6

BNC-210 is under investigation in clinical trial NCT04951076 (A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-traumatic Stress Disorder (PTSD)).

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BNC105 DB06313
small molecule | CAS: 945772-45-2

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesEthersHeterocyclic Compounds, Fused-Ring +3
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BNT-162A1 DB16402
biotech | CAS: 2417899-74-0

BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +10
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BNT111 DB18177
biotech

BNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.

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biotech

BNT162a1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intram…

Kategori:
Experimental Unapproved Treatments for COVID-19
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biotech

BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) …

Kategori:
Amino Acids, Peptides, and ProteinsAntigensBiological Factors +11
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BNT162b2 Omicron (KP.2) Approved DB19415
biotech

BNT162b2 Omicron (KP.2) is COVID-19 mRNA vaccine encoding the viral spike (S) glycoprotein of SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient in the 2024-2025 formulation of Pfizer-BioNTech's Comirnaty vaccine.[L36030]

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BNT162b3 DB16442
biotech

The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to [BNT162b2], BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinica…

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biotech

BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery v…

Kategori:
Experimental Unapproved Treatments for COVID-19
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BO-653 DB19216
small molecule | CAS: 157360-23-1

BO-653 is under investigation in clinical trial NCT00055510 (A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-angioplasty Blood Vessel …

Kategori:
Heterocyclic Compounds, Fused-Ring
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small molecule

Deskripsi belum tersedia.

Target Protein:
D-alanyl-D-alanine carboxypeptidase DacAD-alanyl-D-alanine carboxypeptidase DacA
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Boceprevir Approved DB08873
small molecule | CAS: 394730-60-0

Boceprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine…

Kategori:
Amino AcidsAmino Acids, CyclicAmino Acids, Peptides, and Proteins +21
Target Protein:
Genome polyproteinGenome polyprotein
Waktu ParuhBoceprevir has a me…
Vol. DistribusiThe mean apparent v…
KlirensBoceprevir has a me…
Genetik -
Bocidelpar DB16906
small molecule | CAS: 2095128-20-2

Deskripsi belum tersedia.

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small molecule | CAS: 2356354-82-8

Deskripsi belum tersedia.

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Bococizumab DB12456
biotech | CAS: 1407495-02-6

Bococizumab has been used in trials studying the treatment and prevention of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +11
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Boldenone DB01541
small molecule | CAS: 846-48-0

Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.

Kategori:
Anabolic AgentsAndrostanesAndrostenes +9
Target Protein:
Androgen receptor
Waktu Paruh14 days
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small molecule | CAS: 13103-34-9

Deskripsi belum tersedia.

Kategori:
AndrostanesAndrostenesAndrostenols +6
Target Protein:
Androgen receptor
Waktu Paruh14 days
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Genetik -
Boldo leaf extract Approved DB15815
biotech

Boldo leaf extract allergenic extract is used in allergenic testing.

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Bombesin DB11724
small molecule | CAS: 31362-50-2

Bombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volu…

Kategori:
Amino Acids, Peptides, and ProteinsAmphibian VenomsBiological Factors +12
Target Protein:
Gastrin-releasing peptide receptorBombesin receptor subtype-3Neuromedin-B receptor
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Bombyx mori fiber Approved DB10609
biotech

Bombyx mori fiber is used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
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Bomedemstat DB17234
small molecule | CAS: 1990504-34-1

Deskripsi belum tersedia.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
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biotech | CAS: 2364477-20-1

Deskripsi belum tersedia.

Kategori:
Adeno-associated Viral Vector Therapies
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Bopindolol DB08807
small molecule | CAS: 62658-63-3

Bopindolol (INN) is an ester prodrug for the beta blocker [pindolol].

Kategori:
Adrenergic AgentsAdrenergic AntagonistsAdrenergic beta-Antagonists +12
Target Protein:
Beta-1 adrenergic receptorBeta-2 adrenergic receptorBeta-3 adrenergic receptor +2
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Borage oil Approved DB11238
biotech

Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as an herbal treatment of skin disorders including eczema, seborrheic dermatitis, and neurode…

Kategori:
Agents that reduce seizure thresholdAntirheumatic AgentsBiological Products +11
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biotech

Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) is a vaccine that contains inactivated acellular pertussis antigen that is isolated from Bordetella pertussis culture.

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
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biotech

Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae (Fim2 and Fim3).

Kategori:
Actively Acquired ImmunityInactivated Bordetella Pertussis Vaccine
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biotech

Bordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis [A31248].

Kategori:
Amino Acids, Peptides, and ProteinsBacterial ProteinsBacterial Toxins +7
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