Hasil Filter

6694

Total database: 17430
Struktur (SMILES)
4518 (67.5%)
Target
3751 (56.0%)
Genomik
81 (1.2%)
Referensi
6694 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (6694)

Halaman 67 / 134
IMT504 DB17792
biotech

IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.[A259467]

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleotidesOligonucleotides +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
IN01 DB16434
biotech

The IN01 Vaccine, sponsored by the Instituto Oncologico Dr Rosell, IN3BIO, and PANGAEA, is a compound containing recombinant bacteria[L30543]. These cultures contain EGF-4-EGF with the cholera toxin B-subunit domain G33D sequence[L30543]. Administration of th…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. This strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolac…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells[A219758]. This vaccine specifically was developed in collaboration with the Chinese Academy of Medical Sciences, West Chin…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inbakicept DB16479
biotech | CAS: 2135939-52-3

Inbakicept is a dimeric human IL-15 receptor ? (IL-15R?) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing [nogapendekin alfa], where a single inbakicept is complexed with two noga…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsExperimental Unapproved Treatments for COVID-19 +4
Target Protein:
Interleukin-2 receptor subunit betaCytokine receptor common subunit gamma
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Incadronic acid DB06255
small molecule | CAS: 124351-85-5

Incadronate, or YM-175,[A202769] is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy,[A202862] it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427…

Kategori:
Antineoplastic AgentsBisphosphonatesBone Density Conservation Agents +2
Target Protein:
Farnesyl pyrophosphate synthaseCaspase-3Caspase-4 +1
Waktu ParuhIncadronate has a b…
Vol. Distribusi-
Klirens-
Genetik -
INCB-057643 DB16054
small molecule | CAS: 1820889-23-3

INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).

Kategori:
AcidsAcids, NoncarboxylicAntineoplastic Agents +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
INCB-086550 DB18901
small molecule | CAS: 2230911-59-6

INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inclisiran Approved DB14901
biotech | CAS: 1639324-58-5

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCS…

Kategori:
Antisense Elements (Genetics)Compounds used in a research, industrial, or household settingDiagnostic Uses of Chemicals +16
Target Protein:
Proprotein convertase subtilisin/kexin type 9
Waktu ParuhThe terminal elimin…
Vol. DistribusiThe apparent volume…
KlirensThere is limited in…
Genetik -
Incyclinide DB11647
small molecule | CAS: 15866-90-7

Incyclinide has been used in trials studying the treatment of HIV Infection, AIDS-related Kaposi Sarcoma, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific.

Kategori:
Naphthacenes
Target Protein:
72 kDa type IV collagenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indacaterol Approved DB05039
small molecule | CAS: 312753-06-3

Indacaterol is a novel, ultra-long-acting, rapid onset ?(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 20…

Kategori:
Adrenergic AgonistsAdrenergic beta-2 Receptor AgonistsAdrenergic beta-Agonists +17
Target Protein:
Beta-2 adrenergic receptor
Waktu ParuhIndacaterol serum c…
Vol. DistribusiAfter intravenous i…
KlirensRenal clearance of …
Genetik -
Indapamide Approved DB00808
small molecule | CAS: 26807-65-8

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension.[A204155] Characterized by an office blood pressure of ?140/90, hypertension is pervasive and impacts an estimated…

Kategori:
AmidesAntihypertensive AgentsAntihypertensive Agents Indicated for Hypertension +26
Target Protein:
Solute carrier family 12 member 3Potassium voltage-gated channel subfamily KQT member 1
Waktu ParuhIndapamide is chara…
Vol. DistribusiSome sources report…
KlirensIndapamide's renal …
Genetik -
biotech

Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indigotindisulfonic acid Approved DB11577
small molecule | CAS: 483-20-5

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in …

Kategori:
Coloring AgentsCompounds used in a research, industrial, or household settingDiagnostic Agents +5
Target Protein:
Alpha adrenergic receptor
Waktu ParuhIn healthy adults g…
Vol. DistribusiThe volume of distr…
KlirensIn healthy adults g…
Genetik -
Indinavir Approved DB00224
small molecule | CAS: 150378-17-9

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +33
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh1.8 (± 0.4) …
Vol. Distribusi-
Klirens-
Genetik -
Indium DB11659
small molecule | CAS: 7440-74-6

Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma.

Kategori:
AnionsElectrolytesElements +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 chloride Approved DB09490
small molecule | CAS: 50800-85-6

Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxeta…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu Paruh2.8 days
Vol. DistribusiIndium In-111 Chlor…
KlirensIndium In-111 Chlor…
Genetik -
biotech | CAS: 138661-00-4

Indium In-111 imciromab pentetate is a mouse monoclonal antibody labelled with the radioisotope Indium-111 which was used for cardiac imaging under the trade name Myoscint, but was withdrawn in 1993.

Kategori:
Diagnostic Radiopharmaceuticals
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indium In-111 oxyquinoline Approved DB09473
small molecule | CAS: 65389-08-4

Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron ca…

Kategori:
Radioactive Diagnostic AgentRadiopharmaceutical Activity
Waktu ParuhIndium In 111 decay…
Vol. Distribusi-
KlirensClearance from whol…
Genetik -
Indium In-111 pentetate Approved DB09425
small molecule | CAS: 135998-32-2

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.

Kategori:
Central Nervous SystemDiagnostic RadiopharmaceuticalsRadioactive Diagnostic Agent +1
Waktu ParuhIndium 111 decays b…
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 138955-27-8

Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.

Kategori:
AcetatesAcids, AcyclicAmines +14
Target Protein:
Tumor-associated glycoprotein 72 (TAG-72)
Waktu Paruh0.8 hours (mammalia…
Vol. Distribusi-
Klirens-
Genetik -
Indocyanine green acid form Approved DB09374
small molecule | CAS: 28782-33-4

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl…

Kategori:
BSEP/ABCB11 SubstratesCardiac FunctionColoring Agents +6
Waktu ParuhICG has a half-life…
Vol. DistribusiICG distribution in…
KlirensClearance of dyes w…
Genetik -
small molecule | CAS: 87-51-4

Deskripsi belum tersedia.

Kategori:
Growth SubstancesHeterocyclic Compounds, Fused-RingIndoles +1
Target Protein:
Group IIE secretory phospholipase A2S-phase kinase-associated protein 1Kynurenine--oxoglutarate transaminase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 830-96-6

Deskripsi belum tersedia.

Kategori:
Acids, AcyclicFatty AcidsFatty Acids, Volatile +2
Target Protein:
Group IIE secretory phospholipase A2Aspartate aminotransferaseAromatic-amino-acid aminotransferase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indomethacin Approved DB00328
small molecule | CAS: 53-86-1

Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an ind…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +49
Target Protein:
Prostaglandin G/H synthase 2Phospholipase A2, membrane associatedHuman Cyclooxygenases +8
Waktu ParuhIndometacin disposi…
Vol. DistribusiThe volume of distr…
KlirensIn a clinical pharm…
Genetik -
Indoprofen DB08951
small molecule | CAS: 31842-01-0

A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +18
Target Protein:
C-X-C chemokine receptor type 1Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1 +3
Waktu Paruh2.3 hours.
Vol. Distribusi-
KlirensRenal.
Genetik -
Indoximod DB12827
small molecule | CAS: 110117-83-4

Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

Kategori:
Amino AcidsAmino Acids, AromaticAmino Acids, Cyclic +2
Target Protein:
Indoleamine 2,3-dioxygenase 1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indoxyl sulfate DB07992
small molecule | CAS: 487-94-5

Deskripsi belum tersedia.

Kategori:
Heterocyclic Compounds, Fused-RingIndoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Indralin DB18220
small molecule | CAS: 156691-86-0

Deskripsi belum tersedia.

Kategori:
Benzene DerivativesReceptors, Retinoic Acid, agonistsSulfur Compounds
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 1514889-12-3

Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inebilizumab Approved DB12530
biotech | CAS: 1299440-37-1

Inappropriate growth of or self-directed antibody production by B-cells is the etiological underpinning of a variety of conditions, including the multiple sclerosis-like neurological condition neuromyelitis optica spectrum disorder (NMOSD).[A214283, A214286] …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +12
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhInebilizumab exhibi…
Vol. DistribusiInebilizumab has an…
KlirensInebilizumab has an…
Genetik -
Inecalcitol DB04796
small molecule | CAS: 163217-09-2

Deskripsi belum tersedia.

Kategori:
CholestanesCholestenesFused-Ring Compounds +9
Target Protein:
Vitamin D3 receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Inetetamab DB17457
biotech

Inetetamab is a trastuzumab analog. It differs from trastuzumab by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of trastuzumab.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Infigratinib Approved DB11886
small molecule | CAS: 872511-34-7

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth.[A235174] Cholangiocarcinoma is the most com…

Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents +24
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3 +1
Waktu ParuhThe geometric mean …
Vol. DistribusiAt steady state, th…
KlirensThe geometric mean …
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInactivated Influenza A Virus VaccineInfluenza Vaccines +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune…

Kategori:
Inactivated Influenza A Virus VaccineInfluenza VaccinesVaccines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Kategori:
Actively Acquired ImmunityInfluenza VaccinesLive Attenuated Influenza A Virus Vaccine +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Menampilkan 3301–3350 dari 6694
Sebelumnya Halaman 67 / 134 Berikutnya