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14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
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112 (0.8%)
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14494 (100.0%)

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Hasil Pencarian (14494)

Halaman 66 / 290
BF-1 DB06029
small molecule | CAS: 518980-66-0

BF-1 is an investigational 5-HT2B receptor antagonist developed for the prophylaxis of Migraines.

Target Protein:
5-hydroxytryptamine receptor 2B
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BF-37 DB05755
small molecule

BF-37 for the treatment of atopic dermatitis and/or psoriasis. The active ingredient in BF-37 is Riluzole, applied in a topical formulation, which is believed to correct the imbalances of the immune system that cause atopic dermatitis or psoriasis.

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BF-844 DB17801
small molecule | CAS: 1404506-35-9

Deskripsi belum tersedia.

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BFH772 DB16035
small molecule | CAS: 890128-81-1

BFH772 is under investigation in clinical trial NCT01449591 (Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients).

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Bfpet F-18 DB15424
small molecule | CAS: 863644-14-8

Bfpet F-18 is under investigation in clinical trial NCT03265431 (Evaluation of PET/MR in Patients Selected for Ablation Therapy).

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BG-777 DB05839
small molecule

BG-777 is an immunomodulator with proven efficacy against viral and bacterial infections in preclinical studies.

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BG-P-TAT DB18105
small molecule

Deskripsi belum tersedia.

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BG-P400-TAT DB17104
small molecule

Deskripsi belum tersedia.

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BG1805 DB18667
biotech

BG1805 is an investigational anti-CLL1 chimeric antigen receptor (CAR) T-cell therapy.

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BGA002 DB17125
biotech

Deskripsi belum tersedia.

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BGB-DXP593 DB16357
biotech

BGB-DXP593 is a SARS-CoV-2 neutralizing antibody.[L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With…

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BGT-DTDS DB18664
biotech

BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human _SLC6A3_ gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).

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BHT-3034 DB18045
biotech

BHT-3034 is a DNA plasmid vaccine immunotherapy under investigation for the treatment of myasthenia gravis.[L48086]

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BHV-5000 DB17817
small molecule

BHV-5000 is an orally bioavailable, low-trapping, potent N-methyl-D-aspartate (NMDA) receptor antagonist. The active metabolite of BHV-5000 is [lanicemine].[L46446]

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BI 2536 DB16107
small molecule | CAS: 755038-02-9

BI 2536 is under investigation in clinical trial NCT00376623 (Efficacy and Safety of BI 2536 in Advanced or Metastatic Non Small Cell Lung Cancer).

Kategori:
Antimitotic AgentsHeterocyclic Compounds, Fused-Ring
Target Protein:
Serine/threonine-protein kinase PLK1
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BI 44370 TA DB16037
small molecule | CAS: 866086-05-7

BI 44370 TA is under investigation in clinical trial NCT00751803 (BI 44370 TA in Acute Migraine Attack).

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BI-1206 DB17429
biotech

BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.

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BI-187004 DB18897
small molecule | CAS: 1303515-32-3

Deskripsi belum tersedia.

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BI-671800 DB12524
small molecule | CAS: 1093108-50-9

Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +1
Target Protein:
Prostaglandin D2 receptor 2
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BI-765063 DB17482
biotech

BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein ? (SIRP?).

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BI-836826 DB17322
biotech

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +8
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BI-836858 DB17267
biotech | CAS: 2206770-25-2

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +10
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BI-836880 DB17484
biotech

BI-836880 is a humanized bispecific nanobody that targets VEGF and Ang2.

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BI-K0376 DB05858
biotech

BI-K0376 is investigated for use/treatment in acne. BI-K0376 is a solid. It is under investigation by Pfizer and has gone through phase I of the clinical trails.

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Biapenem DB13028
small molecule | CAS: 120410-24-4

Biapenem has been used in trials studying the treatment of Bacterial Infections.

Kategori:
AmidesAnti-Bacterial AgentsAnti-Infective Agents +6
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Bibrocathol DB13818
small molecule | CAS: 6915-57-7

Deskripsi belum tersedia.

Kategori:
Anti-Infective AgentsBenzene DerivativesOphthalmologicals +2
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Bicalutamide Approved DB01128
small molecule | CAS: 90357-06-5

Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.

Kategori:
AmidesAminesAndrogen Receptor Antagonists +31
Target Protein:
Androgen receptor
Waktu Paruh5.9 days
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Klirens* Apparent oral cl=…
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Bicifadine DB04889
small molecule | CAS: 71195-57-8

Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile. Bicifadine was shown to have potent analgesic activity in vivo and was chosen for fu…

Kategori:
AnalgesicsCytochrome P-450 CYP1A2 SubstratesCytochrome P-450 CYP2D6 Substrates +2
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent serotonin transporterD(2) dopamine receptor
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Bicine DB03709
small molecule | CAS: 150-25-4

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, Peptides, and Proteins
Target Protein:
PlasminogenMembrane-bound lytic murein transglycosylase BUDP-galactopyranose mutase
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Bicisate Approved DB11164
small molecule | CAS: 121251-02-3

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPEC…

Kategori:
Diagnostic AgentsDrugs that are Mainly Renally ExcretedRadioactive Diagnostic Agent
Waktu ParuhThe stability of bi…
Vol. DistribusiAfter intravenous a…
KlirensThe clearance of bi…
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Bictegravir Approved DB11799
small molecule | CAS: 1611493-60-7

Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677]

Kategori:
Antiinfectives for Systemic UseAntiviral AgentsAntivirals for Systemic Use +11
Target Protein:
Reverse transcriptase/RNaseHIntegrase
Waktu ParuhHalf-life is 17.3 h…
Vol. Distribusi0.2 L/Kg in humans …
KlirensBictegravir is main…
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Bicuculline DB11562
small molecule | CAS: 485-49-4

Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

Kategori:
AlkaloidsBenzylisoquinolinesCentral Nervous System Agents +8
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Bicyclol DB16014
small molecule | CAS: 118159-48-1

Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).

Kategori:
Benzene Derivatives
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biotech

Deskripsi belum tersedia.

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Bifenthrin DB15056
small molecule | CAS: 82657-04-3

Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).

Kategori:
Cyclopentane MonoterpenesMonoterpenesSarcoma, Experimental, chemically induced +1
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Bifeprunox DB04888
small molecule | CAS: 350992-10-8

Bifeprunox is a novel atypical antipsychotic agent which, along with SLV313, [aripiprazole] and SSR-181507 combines minimal D2 receptor agonism with 5-HT receptor agonism.

Kategori:
Antipsychotic AgentsAntipsychotic Agents (Second Generation [Atypical])Central Nervous System Depressants +2
Target Protein:
5-hydroxytryptamine receptor 1AD(2) dopamine receptor
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biotech

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Bifidobacterium bifidum Approved DB16538
biotech

Deskripsi belum tersedia.

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biotech

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Bifidobacterium longum Approved DB19248
biotech

Deskripsi belum tersedia.

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biotech

Deskripsi belum tersedia.

Kategori:
Probiotics
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biotech

Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]

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biotech

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Bifikafusp alfa DB19185
biotech | CAS: 1957239-90-5

Bifikafusp alfa is under investigation in clinical trial NCT05329792 (L19IL2/L19TNF in Skin Cancer Patients).

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biotech

Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers).

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BIIB015 DB06304
biotech

BIIB015 is a humanized, IgG1 [immunoglobulin G 1], DM4-Conjugated, anti-cripto, monoclonal antibody. It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +6
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BIIB115 DB18418
biotech

BIIB115 is an investigational antisense oligonucleotide in development for spinal muscular atrophy.

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Bilastine Approved DB11591
small molecule | CAS: 202189-78-4

Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

Kategori:
Antihistamines for Systemic UseDecongestants and AntiallergicsHeterocyclic Compounds, Fused-Ring +8
Target Protein:
Histamine H1 receptor
Waktu ParuhThe mean half life …
Vol. Distribusi-
KlirensBilastine has a tot…
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Bilberry Approved DB14235
biotech

Deskripsi belum tersedia.

Kategori:
AngiospermsBenzopyransBiological Factors +21
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small molecule

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