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14494

Total database: 17430
Struktur (SMILES)
9687 (66.8%)
Target
7525 (51.9%)
Genomik
112 (0.8%)
Referensi
14494 (100.0%)

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Hasil Pencarian (14494)

Halaman 64 / 290
small molecule | CAS: 6336-50-1

Deskripsi belum tersedia.

Kategori:
Antithyroid agentsPyrimidinesPyrimidinones +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech | CAS: 627861-07-8

Beperminogene perplasmid is under investigation in clinical trial NCT02144610 (Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia).

Kategori:
Vasoprotectives
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepotastine Approved DB04890
small molecule | CAS: 125602-71-3

Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe…

Kategori:
Anti-Allergic AgentsDrugs that are Mainly Renally ExcretedHistamine Antagonists +2
Target Protein:
Histamine H1 receptor
Waktu ParuhElimination half li…
Vol. Distribusi-
Klirens-
Genetik -
Bepranemab DB17945
biotech | CAS: 2244960-75-4

Bepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bepridil Approved DB01244
small molecule | CAS: 64706-54-3

A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a cal…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +20
Target Protein:
Voltage-dependent P/Q-type calcium channel subunit alpha-1AVoltage-dependent T-type calcium channel subunit alpha-1HVoltage-dependent calcium channel subunit alpha-2/delta-2 +7
Waktu Paruh24-50 hours
Vol. Distribusi-
Klirens-
Genetik -
Beractant Approved DB06761
biotech | CAS: 108778-82-1

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral li…

Kategori:
Alveolar Surface Tension ReductionBradycardia-Causing AgentsComplex Mixtures +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beraprost DB05229
small molecule | CAS: 88430-50-6

Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.

Kategori:
AnticoagulantsAntiplatelet agentsAutacoids +17
Target Protein:
Prostacyclin receptor
Waktu Paruh35–40 minutes
Vol. Distribusi-
Klirens-
Genetik -
Berbamine DB18146
small molecule | CAS: 478-61-5

Deskripsi belum tersedia.

Kategori:
AlkaloidsAnalgesicsAnalgesics, Non-Narcotic +13
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berberine Approved DB04115
small molecule | CAS: 2086-83-1

An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.

Kategori:
AlkaloidsBenzylisoquinolinesBerberine Alkaloids +1
Target Protein:
Telomerase reverse transcriptaseBaculoviral IAP repeat-containing protein 5HTH-type transcriptional regulator QacR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 1868138-66-2

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berdazimer Approved DB18712
small molecule

Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate…

Kategori:
Macromolecular SubstancesOrganosilicon CompoundsPolymers +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beremagene geperpavec Approved DB17831
biotech | CAS: 2241888-62-8

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolys…

Kategori:
Administration, TopicalCellular and Gene TherapyCicatrizants +2
Waktu ParuhThere is no informa…
Vol. DistribusiThere is no informa…
KlirensThere is no informa…
Genetik -
Bergamot oil DB14335
biotech | CAS: 8007-75-8

Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Kategori:
Biological ProductsComplex MixturesCompounds used in a research, industrial, or household setting +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bergapten DB12216
small molecule | CAS: 484-20-8

Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).

Kategori:
Anti-Inflammatory AgentsAntipsoriaticsAntipsoriatics for Systemic Use +10
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berkelium DB12993
small molecule | CAS: 7440-40-6

Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP-544C).

Kategori:
Actinoid Series ElementsElementsElements, Radioactive +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bermekimab DB14947
biotech | CAS: 1401965-15-8

Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beroctocog alfa Approved DB14473
biotech | CAS: 9001-27-8

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsBlood Coagulation Factors +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berotralstat Approved DB15982
small molecule | CAS: 1809010-50-1

Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE).[L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that pro…

Kategori:
BCRP/ABCG2 SubstratesBlood and Blood Forming OrgansCytochrome P-450 CYP2D6 Inhibitors +16
Target Protein:
Plasma kallikrein
Waktu ParuhFollowing a single …
Vol. DistribusiThe blood to plasma…
KlirensThere is no informa…
Genetik -
Bersacapavir DB19035
small molecule | CAS: 1638266-40-6

Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

Kategori:
Anti-Infective AgentsAntiviral Agents
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersanlimab DB17377
biotech | CAS: 1987854-08-9

Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bersiporocin DB18017
small molecule | CAS: 2241808-52-4

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Bertilimumab DB05429
biotech

Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.

Target Protein:
Eotaxin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berubicin DB17149
small molecule | CAS: 677017-23-1

Deskripsi belum tersedia.

Kategori:
Aminoglycoside AntibacterialsAnti-Bacterial AgentsCarbohydrates +2
Target Protein:
DNA topoisomerase 2-alphaDNA topoisomerase 2-beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Berzosertib DB11794
small molecule | CAS: 1232416-25-9

Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

Target Protein:
Serine/threonine-protein kinase ATR
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besifloxacin Approved DB06771
small molecule | CAS: 141388-76-3

Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +16
Target Protein:
DNA topoisomerase 4 subunit ADNA gyrase subunit BDNA gyrase subunit A +3
Waktu ParuhThe average elimina…
Vol. DistribusiNot absorbed into t…
KlirensN/A
Genetik -
small molecule | CAS: 441785-26-8

Besifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. Besifovir dipivoxil is believed to inhibit viral proliferation…

Kategori:
Heterocyclic Compounds, Fused-RingOrganophosphorus CompoundsPurines +2
Target Protein:
Protein P
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Besilesomab Approved DB13979
biotech | CAS: 537694-98-7

Besilesomab is a mouse monoclonal antibody labelled with the radioactive isotope technetium-99m for determining the location of inflammation/infection in peripheral bone in adults with suspected osteomyelitis [FDA Label]. Utilised only as a diagnostic agent, …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +7
Target Protein:
Carcinoembryonic antigen
Waktu ParuhWhole blood concent…
Vol. DistribusiIn the besilesomab …
KlirensOnce administered i…
Genetik -
Beta carotene Approved DB06755
small molecule | CAS: 7235-40-7

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors.[T162] It is the most abundant form of carote…

Kategori:
Alimentary Tract and MetabolismAlkenesBiological Factors +20
Target Protein:
Free radicals
Waktu ParuhThe apparent half-l…
Vol. DistribusiNo pharmacokinetic …
KlirensThe clearance rate …
Genetik -
Beta vulgaris pollen Approved DB10837
biotech

Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.

Kategori:
Cell-mediated ImmunityIncreased Histamine ReleaseIncreased IgG Production +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 9051-97-2

Deskripsi belum tersedia.

Kategori:
Adjuvants, ImmunologicCarbohydratesExperimental Unapproved Treatments for COVID-19 +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Arabinogalactan endo-beta-1,4-galactanase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beta-3-Cysteine DB02780
small molecule

Deskripsi belum tersedia.

Target Protein:
Envelope glycoprotein gp160
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Alanine DB03107
small molecule | CAS: 107-95-9

beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBU…

Kategori:
AlanineAmino AcidsAmino Acids, Peptides, and Proteins
Target Protein:
Sodium- and chloride-dependent GABA transporter 3Pantothenate synthetase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 477-52-1

beta-Apopicropodophyllin is a component of the freshwater plant _Micranthemum umbrosum_.

Kategori:
Biological ProductsComplex MixturesPlant Extracts +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Pyruvate kinase PKLRGlycerol kinase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7660-25-5

Deskripsi belum tersedia.

Target Protein:
Fucose-binding lectin PA-IIL
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-D-fucose DB04062
small molecule | CAS: 28161-52-6

Deskripsi belum tersedia.

Target Protein:
L-arabinose-binding periplasmic proteinArabinose operon regulatory protein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
CarbohydratesOligosaccharidesPolysaccharides
Target Protein:
Arabinogalactan endo-beta-1,4-galactanase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 18968-14-4

Deskripsi belum tersedia.

Target Protein:
AlgQ1AlgQ2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 14196-86-2

Deskripsi belum tersedia.

Target Protein:
Galectin-7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
6-phospho-beta-galactosidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glycogen phosphorylase, muscle form
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Beta-D-Glucose DB02379
small molecule | CAS: 492-61-5

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Kategori:
CarbohydratesGlucosidesGlycosides +2
Target Protein:
Neutral alpha-glucosidase ABNeutral alpha-glucosidase CHexokinase-4 +91
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 15209-12-8

Deskripsi belum tersedia.

Target Protein:
Glucose-6-phosphate 1-dehydrogenase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 23018-83-9

Deskripsi belum tersedia.

Kategori:
CarbohydratesHexosesMonosaccharides
Target Protein:
Hyaluronate lyaseChondroitinase-ACXylan alpha-1,2-glucuronidase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
beta-Escin DB15774
small molecule | CAS: 26339-90-2

Deskripsi belum tersedia.

Kategori:
CarbohydratesCardiovascular AgentsGlycosides +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Kategori:
Amino AcidsAmino Acids, AcidicAmino Acids, Dicarboxylic +2
Target Protein:
Beta-lactamase TEM
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 300-85-6

Beta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236 (completed for type 1 diabetes), and NCT0558104…

Kategori:
Acids, AcyclicButyratesExperimental Unapproved Treatments for COVID-19 +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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