Digital Pharmacy - Dashboard Peneliti

Alobresib DB14970

small molecule | CAS: 1637771-14-2

Alobresib is under investigation in clinical trial NCT02607228 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer).

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Aloe ferox leaf Approved DB14257

biotech

Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Aloe vera flower Approved DB14254

biotech

Aloe vera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

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Aloe vera leaf DB13906

biotech | CAS: 8001-97-6

Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or _Aloe barbadensis miller_, is the most common species of Aloe that is cultivated for agricultural and medica…

Target Protein:

Free radicals

Waktu ParuhNo pharmacokinetic …

Vol. DistribusiNo pharmacokinetic …

KlirensNo pharmacokinetic …

Genetik -

Aloe vera leaf polysaccharides DB14236

biotech

Deskripsi belum tersedia.

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Alogabat DB18708

small molecule | CAS: 2230009-48-8

Deskripsi belum tersedia.

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Alogliptin Approved DB06203

small molecule | CAS: 850649-61-5

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conve…

Kategori:

Agents causing angioedemaAlimentary Tract and MetabolismBlood Glucose Lowering Agents +15

Target Protein:

Dipeptidyl peptidase 4

Waktu ParuhTerminal half-life …

Vol. DistribusiFollowing a single,…

KlirensRenal clearance = 9…

Genetik -

Aloglutamol DB13650

small molecule | CAS: 13755-41-4

Aloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.

Kategori:

AlcoholsAlimentary Tract and MetabolismAlkalies +13

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Alomfilimab DB16681

biotech | CAS: 2378692-24-9

Alomfilimab is under investigation in clinical trial NCT03829501 (Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer).

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Alosetron Approved DB00969

small molecule | CAS: 122852-42-0

Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) pro…

Kategori:

Alimentary Tract and MetabolismAntidepressive AgentsAntiemetic Serotonin 5-HT3 Receptor Antagonists +23

Target Protein:

5-hydroxytryptamine receptor 3A

Waktu Paruh1.5 hours

Vol. Distribusi* 65 to 95 L

Klirens* 600 mL/min

Genetik -

Alovudine DB06198

small molecule | CAS: 25526-93-6

Deskripsi belum tersedia.

Kategori:

Anti-Infective AgentsAntiviral AgentsDeoxyribonucleosides +3

Target Protein:

Gag-Pol polyproteinReverse transcriptase/RNaseH

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Alovudine F-18 DB14930

small molecule | CAS: 287114-80-1

Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).

Kategori:

Anti-Infective AgentsAntiviral AgentsDeoxyribonucleosides +3

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Aloxiprin DB13509

small molecule | CAS: 9014-67-9

Deskripsi belum tersedia.

Kategori:

AnalgesicsBenzene DerivativesBlood and Blood Forming Organs +6

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Aloxistatin DB18145

small molecule | CAS: 88321-09-9

Deskripsi belum tersedia.

Kategori:

Amino AcidsAmino Acids, Branched-ChainAmino Acids, Essential +6

Target Protein:

Calpain-2 catalytic subunitCathepsin G

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Alpelisib Approved DB12015

small molecule | CAS: 1217486-61-7

Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110? [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological proce…

Kategori:

Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors +32

Target Protein:

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Waktu ParuhThe mean half life …

Vol. DistribusiThe apparent volume…

KlirensThe mean apparent o…

Genetik -

alpha,alpha-Dibromo-D-camphor DB15659

small molecule | CAS: 514-12-5

Deskripsi belum tersedia.

Waktu Paruh-

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alpha,beta-Dehydroaminobutyric acid DB03720

small molecule | CAS: 71018-10-5

Deskripsi belum tersedia.

Waktu Paruh-

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alpha,beta-Methyleneadenosine 5'-triphosphate DB02596

small molecule | CAS: 7292-42-4

Deskripsi belum tersedia.

Kategori:

Adenine NucleotidesAntineoplastic AgentsHeterocyclic Compounds, Fused-Ring +5

Target Protein:

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasePantothenate synthetaseNH(3)-dependent NAD(+) synthetase +5

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ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE DB07332

small molecule

Deskripsi belum tersedia.

Target Protein:

Gag-Pol polyproteinGag-Pol polyprotein

Waktu Paruh-

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Alpha-1-acid glycoprotein DB18601

biotech

Deskripsi belum tersedia.

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Alpha-1-proteinase inhibitor Approved DB00058

biotech | CAS: 9041-92-3

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.

Kategori:

Acute-Phase ProteinsAlpha-GlobulinsAmino Acids, Peptides, and Proteins +21

Target Protein:

Neutrophil elastase

Waktu Paruh-

Vol. Distribusi* 5632 ± 2006 mL [A…

Klirens* 940 +/- 275 mL/da…

Genetik -

Alpha-Adenosine Monophosphate DB03887

small molecule

Deskripsi belum tersedia.

Target Protein:

Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

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Alpha-Amino-2-Indanacetic Acid DB04061

small molecule

Deskripsi belum tersedia.

Waktu Paruh-

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Alpha-Aminobutyric Acid DB04454

small molecule

Deskripsi belum tersedia.

Kategori:

Acids, AcyclicAmino AcidsAmino Acids, Peptides, and Proteins +1

Target Protein:

Glycine amidinotransferase, mitochondrialGag-Pol polyproteinPro-epidermal growth factor +1

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alpha-Amyl cinnamaldehyde Approved DB14175

small molecule | CAS: 122-40-7

alpha-Amyl cinnamaldehyde has a jasmine-like odor and is a widely used synthetic fragrance & suspected allergen. It is used in allergenic testing.

Kategori:

Cell-mediated ImmunityIncreased Histamine ReleasePerfume +1

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alpha-Arbutin Approved DB14109

small molecule | CAS: 84380-01-8

Deskripsi belum tersedia.

Target Protein:

Lysosomal alpha-glucosidase

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Alpha-Benzyl-Aminobenzyl-Phosphonic Acid DB03577

small molecule

Deskripsi belum tersedia.

Target Protein:

Prostatic acid phosphatase

Waktu Paruh-

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alpha-Carotene DB15909

small molecule | CAS: 7488-99-5

Deskripsi belum tersedia.

Kategori:

AlkenesBiological FactorsCyclohexanes +6

Waktu Paruh-

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alpha-Conotoxin VC 1.1 DB05724

small molecule | CAS: 467428-30-4

Deskripsi belum tersedia.

Kategori:

Biological FactorsComplex MixturesMarine Toxins +3

Target Protein:

Neuronal acetylcholine receptor subunit alpha-10

Waktu Paruh-

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Alpha-Cyclodextrin (Cyclohexa-Amylose) DB01909

small molecule | CAS: 10016-20-3

Deskripsi belum tersedia.

Target Protein:

Cyclomaltodextrin glucanotransferase

Waktu Paruh-

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alpha-D-arabinofuranose DB01936

small molecule | CAS: 37388-49-1

Deskripsi belum tersedia.

Target Protein:

Ribokinase

Waktu Paruh-

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alpha-D-Fucopyranose DB03485

small molecule | CAS: 6189-71-5

Deskripsi belum tersedia.

Target Protein:

LactotransferrinL-arabinose-binding periplasmic protein

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Alpha-D-Galactose-1-Phosphate DB02317

small molecule | CAS: 2255-14-3

Deskripsi belum tersedia.

Target Protein:

Beta-phosphoglucomutase

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alpha-D-galacturonic acid DB03511

small molecule | CAS: 6294-16-2

The ?-anomer of D-galacturonic acid.

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alpha-D-glucopyranosyl-2-carboxylic acid amide DB02720

small molecule | CAS: 58825-13-1

Deskripsi belum tersedia.

Target Protein:

Glycogen phosphorylase, muscle form

Waktu Paruh-

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Alpha-D-Glucose 1,6-Bisphosphate DB02835

small molecule | CAS: 10139-18-1

Deskripsi belum tersedia.

Target Protein:

Beta-phosphoglucomutasePhosphoglucomutase-1

Waktu Paruh-

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alpha-D-glucose 6-phosphate DB02007

small molecule | CAS: 15209-11-7

Deskripsi belum tersedia.

Target Protein:

Aldo-keto reductase family 1 member B1Glycogen phosphorylase, muscle formGlutamine--fructose-6-phosphate aminotransferase [isomerizing] +6

Waktu Paruh-

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alpha-D-glucose-1-phosphate DB02843

small molecule | CAS: 59-56-3

Deskripsi belum tersedia.

Kategori:

CarbohydratesHexosephosphatesSugar Phosphates

Target Protein:

Glycogen phosphorylase, muscle formPhosphomannomutase/phosphoglucomutaseMaltodextrin phosphorylase +2

Waktu Paruh-

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Alpha-D-Glucose-1-Phosphate-6-Vanadate DB04397

small molecule

Deskripsi belum tersedia.

Kategori:

Vanadates

Target Protein:

Phosphoglucomutase-1

Waktu Paruh-

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Alpha-D-mannose 1-phosphate DB17678

small molecule | CAS: 15978-07-1

Deskripsi belum tersedia.

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alpha-D-mannose 6-phosphate DB02900

small molecule | CAS: 40436-60-0

Deskripsi belum tersedia.

Target Protein:

Cation-dependent mannose-6-phosphate receptorPhosphomannomutase/phosphoglucomutaseCation-independent mannose-6-phosphate receptor

Waktu Paruh-

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alpha-D-quinovopyranose DB03773

small molecule | CAS: 7658-08-4

The pyranose form of D-quinovose with an ?-configuration at the anomeric position .

Kategori:

CarbohydratesDeoxy Sugars

Target Protein:

Pancreatic alpha-amylaseCyclomaltodextrin glucanotransferaseAlpha-amylase +2

Waktu Paruh-

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alpha-D-Xylopyranose DB03389

small molecule

Deskripsi belum tersedia.

Target Protein:

Chondroitinase-BChondroitinase-ACExoglucanase/xylanase +13

Waktu Paruh-

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alpha-Fluoro-carboxymethyldethia coenzyme A complex DB03182

small molecule

Deskripsi belum tersedia.

Target Protein:

Citrate synthase, mitochondrial

Waktu Paruh-

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alpha-Hydroxy glycineamide DB06568

small molecule

Alpha-hydroxy glycineamide (?HGA) is the active antiviral metabolite of tri-peptide glycyl-prolyl-glycine-amide (GPG-NH2). ?HGA inhibits the replication of HIV-1 in vitro by interfering with the capsid formation. It also has an effect on viral gp160 envelope …

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ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID DB07895

small molecule

Deskripsi belum tersedia.

Kategori:

AlcoholsFatty AlcoholsLipids +3

Target Protein:

Protein farnesyltransferase subunit betaProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Waktu Paruh-

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alpha-Hydroxylinoleic acid DB16027

small molecule | CAS: 57818-44-7

alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).

Kategori:

Fatty AcidsFatty Acids, EssentialFatty Acids, Omega-6 +2

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alpha-Keto-beta-methylvaleric acid DB15831

small molecule | CAS: 1460-34-0

Deskripsi belum tersedia.

Kategori:

Pentanoic Acids

Waktu Paruh-

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alpha-Keto-isoleucine DB15833

small molecule | CAS: 24809-08-3

Deskripsi belum tersedia.

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alpha-Ketoisocaproic acid DB03229

small molecule | CAS: 816-66-0

Deskripsi belum tersedia.

Kategori:

Caproates

Target Protein:

Deacetoxycephalosporin C synthaseD-2-hydroxyisocaproate dehydrogenase

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