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6694

Total database: 17430
Struktur (SMILES)
4518 (67.5%)
Target
3751 (56.0%)
Genomik
81 (1.2%)
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6694 (100.0%)

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Hasil Pencarian (6694)

Halaman 64 / 134
Homosalate Approved DB11064
small molecule | CAS: 118-56-9

Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet…

Kategori:
Acids, CarbocyclicBenzene DerivativesBenzoates +9
Target Protein:
Progesterone receptorAndrogen receptorEstrogen receptor
Waktu ParuhFor local use only,…
Vol. DistribusiFor local use only,…
KlirensFor local use only,…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Thermolysin
Waktu Paruh-
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Hopantenic acid DB14044
small molecule | CAS: 18679-90-8

Hopantenic acid (Pantogam) is a central nervous system depressant. Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115]

Kategori:
Acids, AcyclicAlanineAmino Acids +6
Waktu Paruh-
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Horse chestnut DB13195
biotech

Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are pro…

Kategori:
AngiospermsBiological ProductsCapillary Stabilizing Agents +12
Waktu Paruh-
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biotech

HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific CD4 and CD8 T cell responses.

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HSV-2 theracine DB05811
biotech

HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes.

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HT-0712 DB11650
small molecule | CAS: 617720-02-2

BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).

Kategori:
Piperidines
Target Protein:
3',5'-cyclic-AMP phosphodiesterase 4D3',5'-cyclic-AMP phosphodiesterase 4A3',5'-cyclic-AMP phosphodiesterase 4B
Waktu Paruh-
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biotech

Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated for the treatment of advanced non-small cell lung canc…

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HUB-101 DB18656
biotech

Deskripsi belum tersedia.

Waktu Paruh-
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biotech

Human adenovirus b serotype 7 is a vaccine.

Waktu Paruh-
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biotech

Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.

Kategori:
Actively Acquired ImmunityAdenovirus VaccinesLive Human Adenovirus Type 4 Vaccine +3
Waktu Paruh-
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Genetik -
biotech

Infant botulism is a rare infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission…

Kategori:
Bacterial Neurotoxin NeutralizationHuman Immunoglobulin GPassively Acquired Immunity
Waktu ParuhThe half-life of hu…
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Human calcitonin Approved DB06773
biotech | CAS: 21215-62-3

Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.[A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus …

Kategori:
Bone Density Conservation AgentsCalcitonin PreparationsCalcium Homeostasis +1
Target Protein:
Alpha-actinin-1
Waktu ParuhIntravenous adminis…
Vol. Distribusi-
KlirensThe metabolic clear…
Genetik -
biotech

Human ciliary neurotrophic factor, recombinant was investigated for macular telangiectasia in two clinical trials. The trials were NCT03071965, an extension study of the NT-501 CNTF implant for macular telangiectasia, and NCT01949324, a Phase 2 multicenter ra…

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biotech

Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures…

Kategori:
Allogeneic Cord Blood Hematopoietic Progenitor Cell Therapy
Waktu ParuhPharmacokinetic par…
Vol. DistribusiPharmacokinetic par…
KlirensPharmacokinetic par…
Genetik -
biotech | CAS: 339086-15-6

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntiinfectives for Systemic Use +15
Waktu ParuhIgG1 has a half-lif…
Vol. DistribusiIgG is distributed …
Klirens-
Genetik -
biotech

CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are curre…

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Human immunoglobulin G Approved DB00028
biotech | CAS: 308067-58-5

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatogra…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntigen Neutralization +13
Target Protein:
High affinity immunoglobulin gamma Fc receptor IPutative high affinity immunoglobulin gamma Fc receptor IBLow affinity immunoglobulin gamma Fc region receptor II-a +8
Waktu Paruh>20 hours (mammalia…
Vol. Distribusi-
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biotech

Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are m…

Kategori:
Immunosuppressive AgentsMyelosuppressive Agents
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
biotech

Stem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ESCs are from the inner …

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biotech

Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
Waktu Paruh-
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biotech

Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityAmino Acids, Peptides, and ProteinsCancer immunotherapy +9
Waktu Paruh-
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biotech

Human papillomavirus type 18 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age …

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
Waktu Paruh-
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biotech

Human papillomavirus type 31 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
Waktu Paruh-
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Genetik -
biotech

Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
Waktu Paruh-
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biotech

Human papillomavirus type 45 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
Waktu Paruh-
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Genetik -
biotech

Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 5…

Kategori:
Cancer immunotherapyImmunotherapy
Waktu Paruh-
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biotech

Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type …

Kategori:
Cancer immunotherapyImmunotherapy
Waktu Paruh-
Vol. Distribusi-
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Genetik -
biotech

Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age f…

Kategori:
Actively Acquired ImmunityCancer immunotherapyImmunotherapy +1
Waktu Paruh-
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Klirens-
Genetik -
Human Rho(D) immune globulin Approved DB11597
biotech

Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilize…

Kategori:
Amino Acids, Peptides, and ProteinsAntiinfectives for Systemic UseBlood Proteins +9
Target Protein:
Rhesus blood group D antigen
Waktu ParuhThe half life is 16…
Vol. DistribusiA single dose of 30…
KlirensMean systemic clear…
Genetik -
Human thrombin Approved DB11571
biotech | CAS: 9002-04-4

Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This tra…

Kategori:
Blood Coagulation FactorsIncreased Coagulation Factor Activity
Target Protein:
Coagulation factor VCoagulation factor VIIICoagulation factor XI +5
Waktu ParuhDue to the nature o…
Vol. DistribusiDue to the nature o…
KlirensDue to the nature o…
Genetik -
biotech

Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines thes…

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biotech

Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marro…

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biotech

Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBlood Proteins +10
Waktu ParuhThe mean half-life …
Vol. DistribusiThe volume of distr…
KlirensReadily accessible …
Genetik -
biotech

Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma vi…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesBiological Products +13
Waktu ParuhHuman Varicella-Zos…
Vol. DistribusiFollowing intraveno…
Klirens-
Genetik -
HY10275 DB05079
small molecule

HY10275 is a novel compound specifically designed to modulate two key neurobiological mechanisms that interfere with the sleeping process. HY10275 is highly selective for histamine H1 and serotonin 5HT2a, two chemical receptors that are known to impact the ab…

Target Protein:
Histamine H1 receptor5-hydroxytryptamine receptor 2A
Waktu Paruh-
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Hyaluronic acid Approved DB08818
small molecule | CAS: 9004-61-9

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluron…

Kategori:
Adjuvants, ImmunologicBiocompatible MaterialsCarbohydrates +16
Target Protein:
CD44 antigenIntercellular adhesion molecule 1Hyaluronan mediated motility receptor +12
Waktu ParuhWhen injected by th…
Vol. DistribusiThere is limited in…
KlirensThere is limited in…
Genetik -
small molecule | CAS: 9004-61-9

Hyaluronic acid (non-animal stabilized) is under investigation in clinical trial NCT03460158 (Prospective Evaluation of Facial Cosmetic Procedures).

Kategori:
CarbohydratesGlycosaminoglycansPolysaccharides
Waktu Paruh-
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Klirens-
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Adenylosuccinate synthetaseAdenylosuccinate synthetase
Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 503-66-2

Deskripsi belum tersedia.

Kategori:
Hydroxy AcidsIsomerismLactates
Target Protein:
Pimeloyl-[acyl-carrier protein] methyl ester esterase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 7647-01-0

Deskripsi belum tersedia.

Kategori:
Acid PreparationsAcidsAcids, Noncarboxylic +7
Waktu Paruh-
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Hydrocortisone cypionate Approved DB14541
small molecule | CAS: 508-99-6

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +18
Target Protein:
Annexin A1Glucocorticoid receptor11-beta-hydroxysteroid dehydrogenase type 2 +1
Waktu Paruh6-8 hours
Vol. Distribusi-
Klirens-
Genetik -
Hydrocortisone succinate Approved DB14545
small molecule | CAS: 2203-97-6

Deskripsi belum tersedia.

Kategori:
11-Hydroxycorticosteroids17-HydroxycorticosteroidsAdrenal Cortex Hormones +22
Waktu Paruh-
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Hydrogen fluoride Approved DB11072
small molecule | CAS: 7664-39-3

Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as [DB00472] (Prozac). It is used as a chemical reagent in several industrial processes such as oil refinery. It is also …

Kategori:
AcidsAcids, NoncarboxylicDental Agents +1
Waktu Paruh-
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Hydrogen iodide DB15778
small molecule | CAS: 10034-85-2

Deskripsi belum tersedia.

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Hydrogen peroxide Approved DB11091
small molecule | CAS: 7722-84-1

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it…

Kategori:
Alimentary Tract and MetabolismAnionsAnti-Infective Agents +19
Target Protein:
Tyrosine-protein phosphatase non-receptor type 1
Waktu Paruh-
Vol. DistribusiTarget organs affec…
Klirens-
Genetik -
small molecule | CAS: 97281-48-6

Deskripsi belum tersedia.

Waktu Paruh-
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biotech | CAS: 8016-70-4

Extracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. According to the FDA, hydrogenated soybean oil is generally recognized as safe (G…

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small molecule | CAS: 23599-55-5

Deskripsi belum tersedia.

Kategori:
Biological FactorsHeterocyclic Compounds, Fused-RingPigments, Biological +1
Target Protein:
Precorrin-8X methylmutase
Waktu Paruh-
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Hydroquinone Approved DB09526
small molecule | CAS: 123-31-9

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, b…

Kategori:
AntioxidantsBenzene DerivativesBiological Factors +11
Target Protein:
TyrosinaseIntegrin beta-3Integrin alpha-IIb +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
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